Results 151 to 160 of about 241,530 (273)

Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications

MedComm, Volume 7, Issue 2, February 2026.
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin, Minying Xiong, Aimin Jiang, Li Chen, Lihaoyun Huang, Kailai Li, Hank Z. H. Wong, Jian Zhang, Zaoqu Liu, Quan Cheng, Bufu Tang, Pengpeng Zhang, Peng Luo   +12 more
wiley   +1 more source

Specialized osmotic stress response systems involve multiple SigB-like sigma factors in Streptomyces coelicolor [PDF]

, 2003
Buttner, Mark J., Dale, Glenn E., Kelemen, Gabriella H., Nguyen, Kien T., Thompson, Charles J., Viollier, Patrick H.   +5 more
core   +1 more source

Discovery of murayaquinone from an endophytic bacterium Streptomyces sp. AN140557 as a potent inhibitor of the pine wood nematode, Bursaphelenchus xylophilus

Pest Management Science, Volume 82, Issue 2, Page 1765-1775, February 2026.
Murayaquinone isolated from the pine endophyte Streptomyces sp. AN140557 exhibits potent, dose‐dependent nematicidal activity and egg‐hatching inhibition against the pine wood nematode. It effectively inhibited pine wilt disease in greenhouse tests, suggesting potential as a promising biocontrol agent.
Min‐Kyoung Kang, Hyeon‐Ji Kim, Jong‐Hoon Kim   +2 more
wiley   +1 more source

Development and Application of a Cumate‐Inducible Promoter, Pgc, in Komagataella pastoris

Microbial Biotechnology, Volume 19, Issue 2, February 2026.
A novel cumate‐inducible promoter, Pgc, was engineered in P. pastoris by optimising the CuO operator and CymR repressor (A). This system achieved an approximately 11‐fold increase in recombinant protein production upon induction (B). ABSTRACT Komagataella pastoris is extensively used as a microbial cell factory for the production of recombinant ...
Jiachen Xie, Yazhu Xing, Huiying Luo, Yuan Wang, Wei Zhang, Nan Xu, Bo Liu   +6 more
wiley   +1 more source

Systemic Activation of the Antioxidant System by Root Priming With Non‐Pathogenic Fusarium oxysporum in Flax Infected With Pathogenic Fusarium oxysporum

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Fusarium oxysporum Fo47 primes flax by locally suppressing pathogens in roots and systemically activating antioxidant defences in shoots, offering a sustainable plant protection strategy. ABSTRACT Plants rely on specialised adaptive mechanisms to enhance resistance against environmental stress.
Marta Burgberger, Justyna Mierziak, Wioleta Wojtasik   +2 more
wiley   +1 more source

Rapid risk assessment on acute reference dose (ARfD) of cereulide in infants and information on acute consumption of infant formulae

EFSA Journal, Volume 24, Issue 2, February 2026.
Abstract EFSA has received a request for a rapid risk assessment for cereulide from the European Commission. Cereulide is a heat‐stable emetic toxin produced by Bacillus cereus, recently detected in infant formulae from multiple manufacturers. This led to precautionary recalls across several countries.
European Food Safety Authority (EFSA), Chantra Eskes, José Cortiñas‐Abrahantes, Bernard Bottex, Jean‐Lou C. M. Dorne, Bruno Dujardin, Rita Ferreira de Souza, Zsuzsanna Horvath, Eirini Kouloura, Luisa Ramos Bordajandi, Valentina Rizzi, Hans Steinkellner, Mary Gilsenan   +12 more
wiley   +1 more source

Pseudotetraivprolide aus Pseudomonas entomophila liefern Einblicke in die Biosynthese von Detoxin/Rimosamid‐ähnlichen Anti‐Antibiotika

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Pseudotetraivprolid ist ein neuer Akteur unter den Detoxin/Rimosamid‐ähnlichen Naturstoffen. Die Biosynthese erfordert FabD aus dem Primärstoffwechsel und einen PipDFG‐Komplex für die Acetylierung im letzten Schritt – wodurch schließlich die anti‐antibiotische Wirkung entsteht.
Edna Bode, Julia Büllesbach, Kevin Bauer, Yan‐Ni Shi, Simon Reiners, Ziheng Cui, Petra Happel, Yi‐Ming Shi, Kevin Hoffmann, Peter Grün, Bianca Pommerenke, Uli Kazmaier, Martin Grininger, Helge B. Bode   +13 more
wiley   +1 more source

MICROORGANISMOS BENÉFICOS EN EL CONTROL DE ENFERMEDADES EN JENGIBRE

Agronomía Costarricense, 2005
En Peñas Blanca, San Ramón de Alajuela, se evaluó la acción supresora de las cepas de Trichoderma viride 2C-PR, Bacillus subtilis 002R y Streptomyces griseus 001, en el combate de Fusarium solani, Rhizoctonia solani, Pseudomonas sp y Erwinia ...
Marena Chavarría, Lidieth Uribe, Andrea Bolaños   +2 more
doaj  

Pseudotetraivprolides from Pseudomonas entomophila Provide Insights into the Biosynthesis of Detoxin/Rimosamide‐Like Anti‐Antibiotics

Angewandte Chemie International Edition, Volume 65, Issue 4, 22 January 2026.
Pseudotetraivprolide is a new player among the Detoxin/Rimosamide‐like natural products! Its biosynthesis requires FabD from primary metabolism and a PipDFG complex for final‐step acetylation – unlocking its anti‐antibotic activity. Abstract Novel variants of known natural product (NP) classes can provide valuable insights into their biosynthesis ...
Edna Bode, Julia Büllesbach, Kevin Bauer, Yan‐Ni Shi, Simon Reiners, Ziheng Cui, Petra Happel, Yi‐Ming Shi, Kevin Hoffmann, Peter Grün, Bianca Pommerenke, Uli Kazmaier, Martin Grininger, Helge B. Bode   +13 more
wiley   +1 more source

Design eines aus der Fettsäuresynthase der Maus abgeleiteten Multienzyms für die kompartimentierte chemo‐enzymatische Synthese von 2‐Pyron‐Polyketiden

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Die 4‐Cumarate‐Ligase (4CL1) aus Piper methysticum wurde mit einer nicht‐reduzierenden murinen Fettsäuresynthase verknüpft. Eine direkte Acylierung des ACP durch 4CL1 wurde beobachtet. Die Ketosynthase (KS) wurde so verändert, dass sie das nicht‐kanonische Zimtsäure‐Substrat akzeptiert.
Felix Lehmann, Nadja Joachim, Carolin Parthun, Martin Grininger   +3 more
wiley   +1 more source