Results 61 to 70 of about 981,404 (392)
Nurses\u27 Alumnae Association Bulletin - Volume 3 Number 6 [PDF]
, 1945 My Thirty Months in a Jap Camp Alumnae Day Hi-Lights of the Alumnae Association Meetings New Linen System at Jefferson Welcome! Miss Jackson Condolences and Miscellaneous Items A Step Forward Bits of Chatter Concerning Jefferson Streptomycin Improvements
Jackson, Margaret M, Ullom, Madeline
core +1 more source
Antibacterial Effects of the Essential Oils of CommonlyConsumed Medicinal Herbs Using an In Vitro Model. [PDF]
, 2010 The chemical composition and antibacterial activity of essential oils from 10 commonly consumed herbs: Citrus aurantium, C. limon, Lavandula angustifolia, Matricaria chamomilla, Mentha piperita, M.
Brkic, D. +4 more
core +2 more sources
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
PLoS Neglected Tropical Diseases, 2014 Background Buruli Ulcer (BU) is a tropical infectious skin disease that is currently treated with 8 weeks of intramuscular streptomycin and oral rifampicin. As prolonged streptomycin administration can cause both oto- and nephrotoxicity, we evaluated its
S. Klis +5 more
semanticscholar +1 more source
Resistance patterns of Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients in Nairobi [PDF]
, 2011 Introduction: In Kenya, which ranks thirteenth of 27 high tuberculosis burden countries, diagnosis is based on Ziehl-Neelsen staining alone and patients are treated without information on sensitivity patterns.
Kariuki, Samuel +3 more
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Pseudouridine Synthase RsuA Confers a Survival Advantage to Bacteria under Streptomycin Stress
Antibiotics, 2023 Bacterial ribosome small subunit rRNA (16S rRNA) contains 11 nucleotide modifications scattered throughout all its domains. The 16S rRNA pseudouridylation enzyme, RsuA, which modifies U516, is a survival protein essential for bacterial survival under ...
Sudeshi M. Abedeera +4 more
doaj +1 more source
Streptomycin potency is dependent on MscL channel expression
Nature Communications, 2014 The antibiotic streptomycin is widely used in the treatment of microbial infections. The primary mechanism of action is inhibition of translation by binding to the ribosome, but how it enters the bacterial cell is unclear.
I. Iscla +4 more
semanticscholar +1 more source
Transient Loss of Plasmid Mediated Mercuric Ion Resistance After Freezing and Thawing of Pseudomonas Auerginosa [PDF]
, 1982 Author Institution: Department of Biological Sciences, Wright State UniversityAfter freezing and thawing, Pseudomonas aeruginosa harboring a drug resistance plasmid (Hg , Strep ), became acutely sensitive to mercuric ions but not to streptomycin in the ...
Calcott, Peter H.
core
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source