Results 1 to 10 of about 337,689 (296)

Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells

open access: yeseLife, 2022
Acute myeloid leukaemia (AML) cells interact and modulate components of their surrounding microenvironment into their own benefit. Stromal cells have been shown to support AML survival and progression through various mechanisms.
Nuria Vilaplana-Lopera   +18 more
doaj   +1 more source

The Effect of Mesenchymal Stromal Cells Derived From Endometriotic Lesions on Natural Killer Cell Function

open access: yesFrontiers in Cell and Developmental Biology, 2021
Endometriosis is an inflammatory disease that presents with ectopic endometriotic lesions. Reduced immunosurveillance of these lesions has been proposed to be playing a role in the pathology of endometriosis.
Fawaz Abomaray   +7 more
doaj   +1 more source

Stromal cells in the tumor microenvironment: accomplices of tumor progression?

open access: yesCell Death and Disease, 2023
The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular component), and cellular components include cancer cells and non-malignant cells such as immune cells and stromal cells.
Yan Zhao   +9 more
doaj   +1 more source

Spontaneous cancer-stromal cell fusion as a mechanism of prostate cancer androgen-independent progression. [PDF]

open access: yesPLoS ONE, 2012
We have previously shown that human prostate cancer cells are capable of acquiring malignant attributes through interaction with stromal cells in the tumor microenvironment, while the interacting stromal cells can also become affected with both ...
Ruoxiang Wang   +7 more
doaj   +1 more source

Umbilical cord mesenchymal stromal cells—from bench to bedside

open access: yesFrontiers in Cell and Developmental Biology, 2022
In recent years, mesenchymal stromal cells (MSCs) have generated a lot of attention due to their paracrine and immuno-modulatory properties. mesenchymal stromal cells derived from the umbilical cord (UC) are becoming increasingly recognized as having ...
Shashank Chetty   +9 more
doaj   +1 more source

Bone marrow mesenchymal stromal cell-derived small extracellular vesicles: A novel therapeutic agent in ischemic heart diseases

open access: yesFrontiers in Pharmacology, 2023
Myocardial injury is a major pathological factor that causes death in patients with heart diseases. In recent years, mesenchymal stromal cells (MSCs) have been generally used in treating many diseases in animal models and clinical trials.
Wenguang Chang, Peifeng Li
doaj   +1 more source

Lymph Node Stromal Cells From Different Draining Areas Distinctly Regulate the Development of Chronic Intestinal Inflammation

open access: yesFrontiers in Immunology, 2021
The balance between the responsiveness of the intestinal immune system and the gut environment is fundamental for the maintenance of intestinal homeostasis, which is required for an adequate recognition of entering antigens.
Marijana Basic   +7 more
doaj   +1 more source

Can a Conversation Between Mesenchymal Stromal Cells and Macrophages Solve the Crisis in the Inflamed Intestine?

open access: yesFrontiers in Pharmacology, 2018
Inflammatory bowel disease (IBD) is a group of chronic inflammatory conditions of the gastrointestinal tract characterized by an exacerbated mucosal immune response.
Laura Hidalgo-Garcia   +3 more
doaj   +1 more source

Mesenchymal stromal cell therapy for damaged retinal ganglion cells, is gold all that glitters?

open access: yesNeural Regeneration Research, 2019
Mesenchymal stromal cells are an excellent source of stem cells because they are isolated from adult tissues or perinatal derivatives, avoiding the ethical concerns that encumber embryonic stem cells.
Fernando Lucas-Ruiz   +8 more
doaj   +1 more source

Stromal cell inhibition of anti-CD20 antibody mediated killing of B-cell malignancies

open access: yesFrontiers in Cell and Developmental Biology, 2023
Introduction: The glycoengineered type II anti-CD20 monoclonal antibody obinutuzumab has been licensed for treatment in follicular non-Hodgkin lymphoma and B-CLL following clinical trials demonstrating superior outcomes to standard of care treatment ...
Ester Fagnano   +10 more
doaj   +1 more source

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