Results 121 to 130 of about 10,958,156 (341)

Large-scale structural analysis of the core promoter in mammalian and plant genomes [PDF]

open access: yes, 2005
DNA encodes at least two independent levels of functional information. The first level is for encoding proteins and sequence targets for DNA-binding factors, while the second one is contained in the physical and structural properties of the DNA molecule ...
Florquin, Kobe   +4 more
core   +1 more source

The structure of porcine protegrin genes

open access: yesFEBS Letters, 1995
We cloned the genes of three protegrins, a family of cathelin‐associated antimicrobial peptides originally isolated from porcine leukocytes. Each gene comprised 4 exons and 3 introns, wherein Exon I encoded the signal sequence and the first 37 amino acids of cathelin, Exons II and III contained 36 and 24 additional cathelin residues and Exon IV ...
Zhao, Chengquan   +2 more
openaire   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The molecular infrastructure of glutamatergic synapses in the mammalian forebrain

open access: yeseLife
Glutamatergic synapses form the vast majority of connections within neuronal circuits, but how these subcellular structures are molecularly organized within the mammalian brain is poorly understood. Conventional electron microscopy using chemically fixed,
Julia Peukes   +11 more
doaj   +1 more source

Expression of genes involved in cell wall structural components in different genotypes of Theobroma cacao [PDF]

open access: yes, 2011
Resistant in this main way to control witches´ broom resistance, therefore the understanding of pathogen infection and its disease resistance mechanism is very important in order to obtain durable resistance.
Gramacho, Karina Peres   +3 more
core  

Statistical calibration of qRT-PCR, microarray and RNA-Seq gene expression data with measurement error models

open access: yes, 2014
The accurate quantification of gene expression levels is crucial for transcriptome study. Microarray platforms are commonly used for simultaneously interrogating thousands of genes in the past decade, and recently RNA-Seq has emerged as a promising ...
Kuczek, Thomas, Sun, Zhaonan, Zhu, Yu
core   +1 more source

Structure of the Murine VCAM1 Gene

open access: yesGenomics, 1993
The architecture of the murine VCAM1 gene, encoding vascular cell adhesion molecule-1, was determined. its 10 exons span approximately 20 kb. Exon 1 encodes the 5' untranslated region and the signal peptide; exons 2-4 and 6-9, the C2 or H-type immunoglobulin domains; and exon 10, the transmembrane and cytoplasmic domains followed by the entire 3 ...
M I, Cybulsky   +2 more
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Identification of a contemporary human parechovirus type 1 by VIDISCA and characterisation of its full genome

open access: yesVirology Journal, 2008
Background Enteritis is caused by a spectrum of viruses that is most likely not fully characterised. When testing stool samples by cell culture, virus isolates are sometimes obtained which cannot be typed by current methods. In this study we used VIDISCA,
Drexler Jan   +5 more
doaj   +1 more source

Occurrence of antilisterial structural bacteriocins genes in meat borne lactic acid bacteria

open access: yes, 2015
The ability to inhibit the growth of Listeria cells and the presence of bacteriocin encoding genes was examined in 115 LAB strains isolated from Argentinean vacuum-packaged beef and different traditional fermented sausages.
Cecilia A. Fontana   +3 more
semanticscholar   +1 more source

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