Results 111 to 120 of about 10,958,156 (341)

Gene expression drives the evolution of dominance. [PDF]

, 2018
Dominance is a fundamental concept in molecular genetics and has implications for understanding patterns of genetic variation, evolution, and complex traits.
A Durvasula, A Platt, AF Agrawal, B Charlesworth, BM Henn, BY Kim, CD Huber, CD Huber, D Enard, D Ortega-Del Vecchyo, D Szklarczyk, DJ Balick, F Gao, F Manna, FH Shaw, H Kacser, HA Orr, I Frumkin, J Yang, JBS Haldane, JS Sanjak, KE Lohmueller, KM Teshima, LD Hurst, MA DePristo, MJ Simmons, N Phadnis, P Cingolani, P Lamesch, PY Novikova, RA Fisher, RD Hernandez, RN Gutenkunst, S Glémin, S Ossowski, S Williamson, S Wright, SH Williamson, T Bedford, T Kawakatsu, T Mukai, TI Gossmann, TT Hu, X Zheng, YB Simons   +44 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Transcriptome‐Wide Association Analysis of Flavonoid Biosynthesis Genes and Their Correlation With Leaf Phenotypes in Hawk Tea (Litsea coreana var. sinensis)

Ecology and Evolution
Hawk tea (Litsea coreana var. sinensis), derived from the tender shoots or leaves, rich in flavonoids can promote healthcare for humans. The primary flavonoid are kaempferol‐3‐O‐β‐D‐glucoside, kaempferol‐3‐O‐β‐D‐galactoside, quercetin‐3‐O‐β‐D‐glucoside ...
Lan Yang, Huie Li, Na Xie, Gangyi Yuan, Qiqiang Guo   +4 more
doaj   +1 more source

Magmas Gene Structure and Evolution

In Silico Biology: Journal of Biological Systems Modeling and Multi-Scale Simulation, 2005
Magmas is a nuclear encoded protein found in the mitochondria of mammalian cells. It participates in granulocyte-macrophage-colony stimulating factor (GM-CSF) signaling in hematopoietic cells and has an essential role in invertebrate development. In order to characterize the protein structural features and gene evolution of Magmas, a dataset containing
Jianbin Peng, Cheng-Han Huang, Mary K. Short, Paul T. Jubinsky   +3 more
openaire   +3 more sources

The Crc Global Regulator Inhibits the Pseudomonas putida pWW0 Toluene/Xylene Assimilation Pathway by Repressing the Translation of Regulatory and Structural Genes*

Journal of Biological Chemistry, 2010
In Pseudomonas putida, the expression of the pWW0 plasmid genes for the toluene/xylene assimilation pathway (the TOL pathway) is subject to complex regulation in response to environmental and physiological signals.
R. Moreno, P. Fonseca, F. Rojo
semanticscholar   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Surviving a Genome Collision: Genomic Signatures of Allopolyploidization in the Recent Crop Species [PDF]

, 2017
Polyploidization has played a major role in crop plant evolution, leading to advantageous traits that have been selected by humans. Here, we describe restructuring patterns in the genome of Brassica napus L., a recent allopolyploid species.
Chalhoub, Boulos, Samans, Birgit, Snowdon, Rod J.   +2 more
core   +1 more source

Vaccine candidates for dengue virus type 1 (DEN1) generated by replacement of the structural genes of rDEN4 and rDEN4Δ30 with those of DEN1

Virology Journal, 2007
BackgroundAntigenic chimeric viruses have previously been generated in which the structural genes of recombinant dengue virus type 4 (rDEN4) have been replaced with those derived from DEN2 or DEN3.
J. Blaney, Neeraja Sathe, C. Hanson, C. Firestone, B. Murphy, S. Whitehead   +5 more
semanticscholar   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Structural and functional properties of genes involved in human cancer

BMC Genomics, 2006
Background One of the main goals of cancer genetics is to identify the causative elements at the molecular level leading to cancer. Results We have conducted an analysis of a set of genes known to be involved in cancer in order to unveil their unique ...
Ouzounis Christos A, Higgins Desmond G, Furney Simon J, López-Bigas Núria   +3 more
doaj   +1 more source