Results 51 to 60 of about 10,958,156 (341)
Current evidence for a modulation of low back pain by human genetic variants [PDF]
, 2009 The manifestation of chronic back pain depends on structural, psychosocial, occupational and genetic influences. Heritability estimates for back pain range from 30% to 45%. Genetic influences are caused by genes affecting intervertebral disc degeneration Aberle, Agarwal, Agrawal, Aladin, Anderson, Andersson, Annunen, Arnold, Ashford, Atkinson, Bandell, Battie, Battie, Bautista, Bejaoui, Berthele, Beyer, Blau, Bond, Brown, Brown, Brown, Campa, Caraco, Carbonell Sala, Carragee, Cascorbi, Cho, Chou, Chou, Cipollone, Collart, Cox, Dalen, Daly, Dawkins, Dayer, Dayer, Diatchenko, Diatchenko, Diatchenko, Dick, Doehring, Eckhardt, Einarsdottir, Fillingim, Foulkes, Fu, Gasche, Goldberg, Grant, Gross, Gursoy, Gutierrez-Roelens, Hamdani, Hartvigsen, Hayashida, Hernandez, Higashino, Hirose, Hoyland, Hummel, Hustmyer, Ikeda, Indo, Irmgard Tegeder, Jayamanne, Jim, Jörn Lötsch, Kales, Kalichman, Karppinen, Karsak, Kawaguchi, Kawaguchi, Kawasaki, Khoromi, Kim, Kim, Kim, Kim, Kirchheiner, Kirchheiner, Klepstad, Knoeringer, Kroslak, Kuisma, Kung, Lafreniere, Landau, Langdahl, Le Maitre, Lee, Lettre, Leyne, Lichtman, Liem, Lorenzo, Lotsch, Lotsch, Lotsch, Lotsch, Lotsch, Lotsch, Lovlie, Lu, Luoma, Lötsch, MacDonald, Macpherson, Madadi, Manning, McNamara, Meeus, Meller, Meller, Mignat, Mio, Miura, Mogil, Mogil, Morrison, Nguyen, Noponen-Hietala, Noponen-Hietala, Oakley, Oertel, Oertel, Oertel, Ofek, Ohtori, Oliveira, Paassilta, Papafili, Pilotto, Pluijm, Poulsen, Racz, Racz, Rakvag, Ralston, Ralston, Reyes-Gibby, Richards, Riviere, Roddier, Romberg, Russo, Sachse, Sakai, Schmidt, Schneider, Seki, Seki, Sindrup, Sipe, Skarke, Skarke, Slade, Slaugenhaupt, Solovieva, Solovieva, Solovieva, Solovieva, Solovieva, Srinivasan, Srinivasan, Stamer, Stamer, Steward, Stohler, Suzuki, Svendsen, Tadic, Takahashi, Tam, Tander, Tegeder, Tegeder, Thieme, Thomas, Trevisani, Uitterlinden, Ujike, van Meurs, Vargas-Alarcon, Verhoeven, Videman, Videman, Virtanen, Voronov, Vree, Wiesinger, Yamada, Yazdanpanah, Zhang, Zhang, Zhang, Zhang, Zubieta, Zuo +200 morecore +1 more sourcePrenatal exome sequencing analysis in fetal structural anomalies detected by ultrasonography (PAGE): a cohort study
The Lancet, 2019 Summary Background Fetal structural anomalies, which are detected by ultrasonography, have a range of genetic causes, including chromosomal aneuploidy, copy number variations (CNVs; which are detectable by chromosomal microarrays), and pathogenic ...J. Lord, D. McMullan, R. Y. Eberhardt, G. Rinck, S. Hamilton, E. Quinlan-Jones, E. Prigmore, Rebecca Keelagher, Sunayna Best, Georgina K Carey, Rhiannon Mellis, S. Robart, Ian R Berry, K. Chandler, D. Cilliers, L. Cresswell, S. Edwards, C. Gardiner, A. Henderson, S. Holden, T. Homfray, T. Lester, R. Lewis, R. Newbury-Ecob, K. Prescott, O. Quarrell, S. Ramsden, E. Roberts, D. Tapon, Madeleine J Tooley, P. Vasudevan, A. Weber, D. Wellesley, P. Westwood, H. White, M. Parker, Denise Williams, L. Jenkins, R. Scott, M. Kilby, L. Chitty, M. Hurles, E. Maher, M. Bateman, Ian R Berry, Sunayna Best, Carolyn Campbell, Jennie Campbell, Georgina K Carey, K. Chandler, L. Chitty, D. Cilliers, K. Cohen, E. Collingwood, Panayiotis Constantinou, L. Cresswell, C. Delmege, R. Y. Eberhardt, S. Edwards, Richard Ellis, Jerry Evans, Thomas Everett, C. Pinto, N. Forrester, Emma Fowler, C. Gardiner, S. Hamilton, K. Healey, A. Henderson, S. Holden, T. Homfray, Rebecca Hudson, M. Hurles, L. Jenkins, Rebecca Keelagher, M. Kilby, T. Lester, R. Lewis, J. Lord, E. Maher, T. Marton, D. McMullan, S. Mehta, Rhiannon Mellis, R. Newbury-Ecob, Soo-Mi Park, M. Parker, K. Prescott, E. Prigmore, O. Quarrell, E. Quinlan-Jones, S. Ramsden, G. Rinck, S. Robart, E. Roberts, Jay F Rowland, R. Scott, James Steer, D. Tapon, E. Taylor, Madeleine J Tooley, P. Vasudevan, A. Weber, D. Wellesley, P. Westwood, H. White, Denise Williams, Elizabeth Wilson +107 moresemanticscholar +1 more sourceYY1 Is a Structural Regulator of Enhancer-Promoter Loops
Cell, 2017 SUMMARY There is considerable evidence that chromosome structure plays important roles in gene control, but we have limited understanding of the proteins that contribute to structural interactions between gene promoters and their enhancer elements. Large A. Weintraub, Charles H. Li, A. V. Zamudio, A. Sigova, N. Hannett, Daniel S. Day, B. Abraham, Malkiel A. Cohen, Behnam Nabet, Dennis L. Buckley, Y. Guo, Denes Hnisz, R. Jaenisch, J. Bradner, N. Gray, R. Young +15 moresemanticscholar +1 more sourceIntegrated metabolomic and transcriptomic analysis of anthocyanin accumulation mechanisms in maize kernels of different colors
Frontiers in GeneticsIntroductionAnthocyanins are important natural pigments and bioactive compounds in colored maize kernels. Although colored fresh-eating maize has attracted increasing attention because of its nutritional and functional value, the molecular basis ...Chao Jiang, Chao Jiang, Hanbo Shi, Hanbo Shi, Linan Yan, Linan Yan, Wenxu Yin, Wenxu Yin, Hui Li, Hui Li, Haibo Lu, Haibo Lu, Haichao Zhao, Haichao Zhao, Songtao Liu, Songtao Liu, Shuo Wang, Dong Wei, Dong Wei, Zhihong Huang, Zhihong Huang +20 moredoaj +1 more sourceVariantSurvival: a tool to identify genotype–treatment response
Frontiers in Bioinformatics, 2023 Motivation: For a number of neurological diseases, such as Alzheimer’s disease, amyotrophic lateral sclerosis, and many others, certain genes are known to be involved in the disease mechanism. A common question is whether a structural variant in any such Thomas Krannich, Marina Herrera Sarrias, Hiba Ben Aribi, Moustafa Shokrof, Alfredo Iacoangeli, Ammar Al-Chalabi, Fritz J. Sedlazeck, Ben Busby, Ahmad Al Khleifat +8 moredoaj +1 more sourceGenome-wide identification and expression pattern analysis of R2R3-MYB transcription factor gene family involved in puerarin biosynthesis and response to hormone in Pueraria lobata var. thomsonii
BMC Plant Biology, 2023 Background R2R3-MYB transcription factors regulate secondary metabolism, stress responses and development in various plants. Puerarin is a bioactive ingredient and most abundant secondary metabolite isolated from Pueraria lobata.Zhengdan Wu, Wendan Zeng, Changfu Li, Jihua Wang, Xiaohong Shang, Liang Xiao, Sheng Cao, Yansheng Zhang, Shiqiang Xu, Huabing Yan +9 moredoaj +1 more sourceEukaryotic and Prokaryotic Gene Structure [PDF]
SSRN Electronic Journal, 2017 Genes consist of multiple sequence elements that together encode the functional product and regulate its expression. Despite their fundamental importance, there are few freely available diagrams of gene structure. Presented here are two figures that summarise the different structures found in eukaryotic and prokaryotic genes.Thomas Shafee, Rohan Loweopenaire +3 more sources