Results 31 to 40 of about 6,294,780 (309)

Stability of Structured Hamiltonian Eigensolvers [PDF]

SIAM Journal on Matrix Analysis and Applications, 2001
This work concerns the stability of structured Hamiltonian eigensolvers. The structured backward errors are defined. By introducing the symplectic quasi-QR factorization, the structured backward errors can be efficiently computed. A detailed rounding error analysis of some Jacobi-like algorithms is also given.
openaire   +2 more sources

ATP binding to lysozyme and superfolder GFP amyloid fibrils induces aggregate remodeling and attenuates their cytotoxicity

Cell Death Discovery
The pathogenesis of neurodegenerative diseases such as Alzheimer’s and Parkinson’s, systemic and local amyloidoses is closely associated with amyloid fibril accumulation.
Olga V. Stepanenko, Maksim I. Sulatsky, Kristina G. Gridasova, Ekaterina V. Mikhailova, Anna I. Sulatskaya, Olesya V. Stepanenko   +5 more
doaj   +1 more source

Looking at the recent advances in understanding α-synuclein and its aggregation through the proteoform prism [version 1; referees: 2 approved]

F1000Research, 2017
Despite attracting the close attention of multiple researchers for the past 25 years, α-synuclein continues to be an enigma, hiding sacred truth related to its structure, function, and dysfunction, concealing mechanisms of its pathological spread within ...
Vladimir N. Uversky
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Stress-Induced Evolution of the Nucleolus: The Role of Ribosomal Intergenic Spacer (rIGS) Transcripts

Biomolecules
It became clear more than 20 years ago that the nucleolus not only performs the most important biological function of assembling ribonucleic particles but is also a key controller of many cellular processes, participating in cellular adaptation to stress.
Anastasia A. Gavrilova, Margarita V. Neklesova, Yuliya A. Zagryadskaya, Irina M. Kuznetsova, Konstantin K. Turoverov, Alexander V. Fonin   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Molecular basis for PrimPol recruitment to replication forks by RPA

Nature Communications, 2017
PrimPol is a multifunctional replicative enzyme that can bypass DNA damage, as well as reprime replication restart. Here, the authors have elucidated how PrimPol is recruited to stalled replication forks via specific interactions with RPA, which ...
Thomas A. Guilliam, Nigel C. Brissett, Aaron Ehlinger, Benjamin A. Keen, Peter Kolesar, Elaine M. Taylor, Laura J. Bailey, Howard D. Lindsay, Walter J. Chazin, Aidan J. Doherty   +9 more
doaj   +1 more source

Wall deflection induced by pre-excavation dewatering under different construction conditions

Yantu gongcheng xuebao, 2017
The existing field measurements show that the deformation of retaining wall and surrounding environment induced by pre-excavation dewatering can reach centimeter level, but the relevant researches are still less.
ZENG Chao-feng 1, 2, 3, HU Yi1, XUE Xiu-li 1
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

On the Stability of Cooperation Structures [PDF]

, 2002
This paper studies the payoff structure of stable cooperation structures in link formation games. Players choose non-cooperatively with whom they want to form a link, and the payoffs are given by the Myerson value of the cooperation structure obtained.
openaire   +3 more sources