Results 41 to 50 of about 883,699 (268)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Bioinformatics Analysis of the Actin Interactome

Proceedings
Actin is a key protein of the muscle contraction system [...]
Yakov I. Mokin, Olga I. Povarova, Iuliia A. Antifeeva, Konstantin K. Turoverov, Irina M. Kuznetsova, Alexander V. Fonin   +5 more
doaj   +1 more source

A review of recent advances in permeable pipe pile

Yantu gongcheng xuebao, 2017
Soil compaction in the process of pile driving has always plagued engineers. How to speed up the dissipation of excess pore water pressure during the pile driving is the current research focus.
ZENG Chao-feng 1, 2, 3, 4, XUE Xiu-li 3, MEI Guo-xiong 1,2
doaj   +1 more source

Stability of trusses by graphic statics

Royal Society Open Science, 2021
This paper presents a graphical method for determining the linearized stiffness and stability of prestressed trusses consisting of rigid bars connected at pinned joints and which possess kinematic freedoms.
Allan McRobie, Cameron Millar, William F. Baker   +2 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

An unexpected insight into the cause of olfactory dysfunction: fibrillogenesis of odorant-binding proteins

Cell Death Discovery
Olfactory dysfunction is a common complication of serious pathologies, including neurodegenerative disorders, bacterial and viral infections, including COVID-19, and others. Despite the widespread prevalence of olfactory disorders, the pathophysiological
Olga V. Stepanenko, Maksim I. Sulatsky, Anna I. Sulatskaya, Olesya V. Stepanenko   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Structurally unstable quadratic vector fields of codimension two: families possessing a finite saddle-node and an infinite saddle-node

Electronic Journal of Qualitative Theory of Differential Equations, 2021
In 1998, Artés, Kooij and Llibre proved that there exist 44 structurally stable topologically distinct phase portraits modulo limit cycles, and in 2018 Artés, Llibre and Rezende showed the existence of at least 204 (at most 211) structurally unstable ...
Joan Artés, Marcos Mota, Alex Rezende
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Structural basis of Fanconi anemia pathway activation by FANCM

The EMBO Journal
FANCM is crucial in genome maintenance, functioning in the Fanconi anemia (FA) pathway, alternative lengthening of telomeres (ALT), and replication fork protection.
Rohan Bythell-Douglas, Sylvie van Twest, Lara Abbouche, Elyse Dunn, Rachel J Coulthard, David C Briggs, Vincent Murphy, Xinxin Zhang, Winnie Tan, Sarah S Henrikus, Dongming Qian, Yin Wu, Jana Wolf, Laurent Rigoreau, Shabih Shakeel, Kathryn L Chapman, Neil Q McDonald, Andrew J Deans   +17 more
doaj   +1 more source