Results 131 to 140 of about 1,568 (147)

Succinate-SUCNR1 signaling drives Treg-mediated suppression in the solid tumor 4795

The Journal of Immunology
Abstract Description   The success of T cell therapies in solid tumors is limited by the immunosuppressive tumor microenvironment (TME). The secretion of metabolites in the TME directs the immune landscape, acting as signaling molecules regulating immune responses and reducing the efficacy of ...
Sinéad Kinsella, Erin Kirsche, Ian Thompson-Hernandez, Menna Hailemariam, Lauren E. Martin, Francesco Mazziotta, Colton W. Smith, Aude G. Chapuis   +7 more
openaire   +1 more source

SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression

Cell Metabolism, 2023
Carolina Pimenta-Lopes, Sonia Fernandez-Veledo, Catalina Nunez-Roa   +2 more
exaly  

P-98 SUCNR1/SDHA Profiles as Predictors of HNSCC Prognosis

Oral Oncology, 2021
L. Pujol-Vilà, L. Ruiz-Sevilla, L. Rojas-Lechuga, X. Terra, I. Vilaseca, S. Fernandez-Veledo, F.X. Avilés-Jurado   +6 more
openaire   +1 more source

Role of succinate/sucnr1 axis in the development of masld-related HCC

Trabajo presentado en el 50º Congreso anual Asociación Española para el Estudio del Hígado, celebrado en Madrid, del 26 al 28 de febrero de ...
Salmerón Pelado, Laura, Marsal-Beltran, Anna, Rodríguez-Peña, M-Mar, Bertran Rodríguez, Esther, Fabregat Romero, Isabel, Fernández-Fernández, María, Moles, Anna, Vendrell, Joan, Fernández-Veledo, Sonia   +8 more
openaire   +1 more source

Cell selectivity in succinate receptor SUCNR1/GPR91 signaling in skeletal muscle

American Journal of Physiology - Endocrinology and Metabolism, 2023
Anna Krook, Ahmed M Abdelmoez, Mladen Savikj   +2 more
exaly  

TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION

2023
LI XIN, SAXENA DEEPAK, GUO YUQI
openaire   +1 more source

Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine

Proceedings of the National Academy of Sciences of the United States of America, 2018
Peihua Jiang, Makoto Ohmoto, Joseph Urban   +2 more
exaly  

SUCNR1 mediates inflammasome activation: Relevance in Ulcerative Colitis

2021
Bauset C, Lis-Lopez L, Ortiz-Masia D, Gisbert-Ferrandiz L, Coll S, Calatayud S, Barrachina M, Cosin-Roger J   +7 more
openaire   +1 more source

Succinate induces skeletal muscle fiber remodeling via SUCNR1 signaling

EMBO Reports, 2019
Songbo Wang, , Sarah Schaul
exaly  

Succinate Receptor 1 (SUCNR1) Expression in Airway Epithelial Cells

B31. AIRWAY EPITHELIAL INFLAMMATION AND DYSFUNCTION
D.E. Winnica, S. Dawrs, C. Mancuso, S. Ye, F.L. Holguin   +4 more
openaire   +1 more source