Results 51 to 60 of about 674,727 (353)

Synthesis of Asymmetrically Labeled Sucrose by a Recombinant Sucrose Synthase [PDF]

open access: yesBioscience, Biotechnology, and Biochemistry, 1997
About 80% of radioactivity was recovered in asymmetrically labeled sucrose from UDP-[14C]glucose or [14C]fructose with recombinant mung bean sucrose synthase expressed in Escherichia coli harboring pEB-01. This high recovery is due to the fact that the enzyme conserving the activity of sucrose synthase has a similar affinity for UDP-glucose and ...
Takahisa Hayashi   +5 more
openaire   +3 more sources

Sucrose is an early modulator of the key hormonal mechanisms controlling bud outgrowth in Rosa hybrida

open access: yesJournal of Experimental Botany, 2015
Highlight Recent research shows that sugar availability triggers bud outgrowth. This paper further demonstrates that the effect of sucrose involves changes in the hormonal network related to bud outgrowth, and identifies potential hormones involved in ...
F. Barbier   +14 more
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Sucrose transporter2 contributes to maize growth, development, and crop yield.

open access: yesJournal of Integrative Plant Biology, 2017
During daylight, plants produce excess photosynthates, including sucrose, which is temporarily stored in the vacuole. At night, plants remobilize sucrose to sustain metabolism and growth.
K. Leach   +4 more
semanticscholar   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Sucrose diffusion in aqueous solution

open access: yesPhysical Chemistry, Chemical Physics - PCCP, 2016
We report the first direct measurements of sucrose diffusion in aqueous solution at sucrose mass fractions above 0.75.
H. Price, J. Mattsson, B. Murray
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Storage and conversion of Eclipta alba synseeds and RAPD analysis of the converted plantlets

open access: yesBiologia Plantarum, 2010
The encapsulated shoot tips and nodal segments of Eclipta alba were stored at 4, 12 and 20 °C under irradiance of 1.5 gmmol m-2 s-1 and high conversion was observed in synseeds stored at 4 °C for 8 weeks.
A. Ray, S. Bhattacharya
doaj   +1 more source

The sorghum SWEET gene family: stem sucrose accumulation as revealed through transcriptome profiling

open access: yesBiotechnology for Biofuels, 2016
BackgroundSWEET is a newly identified family of sugar transporters. Although SWEET transporters have been characterized by using Arabidopsis and rice, very little knowledge of sucrose accumulation in the stem region is available, as these model plants ...
H. Mizuno, S. Kasuga, H. Kawahigashi
semanticscholar   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

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