Results 61 to 70 of about 1,141 (196)

Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection [PDF]

open access: yes, 2021
Certain sulfated glycans, including those from marine sources, can show potential effects against SARS-CoV-2. Here, a new fucosylated chondroitin sulfate (FucCS) from the sea cucumber Pentacta pygmaea (PpFucCS) (MW ∼10.60 kDa) was isolated and ...
Dwivedi, Rohini   +3 more
core   +2 more sources

Research Review on Inhibitors of Lumpy Skin Disease Virus: From Biological Characteristics, Drug Repurposing, to Computer‐Aided Drug Design

open access: yesInternational Journal of Microbiology, Volume 2026, Issue 1, 2026.
This review summarizes the research progress on inhibitors of lumpy skin disease virus (LSDV), focusing on its biological characteristics and key proteins involved in the viral replication cycle. It compiles various inhibitors (direct‐acting poxvirus inhibitors and host‐directed poxvirus inhibitors) against poxviruses, their mechanisms of action, and ...
Leilei ZHAO   +7 more
wiley   +1 more source

Self-assembled nanoparticles made of fucan [PDF]

open access: yes, 2011
Amphiphilic polymers can self-assemble in water due to hydrophilic and hydrophobic interactions, forming nanoparticles (NPs) with unique physicochemical characteristics and thermodynamic stability.
Almeida-Lima, J.   +6 more
core  

Protein-carbohydrate interactions during fertilization [PDF]

open access: yes, 1998
Interaction between gametes during fertilization is at least in part regulated by carbohydrate moieties of the zona pellucida (ZP) and carbohydrate binding proteins of the sperm surface. This review focuses on the protein-carbohydrate interactions during
Kolle, S., Plendl, J., Sinowatz, Fred
core   +1 more source

Sulfatases: Catalytic Mechanism, Substrate Preferences, and Carbohydrate‐Based Inhibitor Design

open access: yesIsrael Journal of Chemistry, Volume 65, Issue 12, December 2025.
Sulfatases are a class of enzymes that can cleave sulfates from heparan sulfate and modulate many of their biological activities. In this review, following a general introduction on sulfatase, their enzymatic mechanism and substrate scope are discussed.
Morgan Mayieka   +3 more
wiley   +1 more source

Anticancer Effect of Fucoidan in Combination with Tyrosine Kinase Inhibitor Lapatinib [PDF]

open access: yes, 2014
Background:. Despite a number of in vitro and in vivo studies reporting the efficacy of fucoidan in treating various cancers, few studies have measured the efficacy of dietary fucoidan (DF) in combination with cancer drugs.
Kim, Jihun   +3 more
core   +3 more sources

Structural Characterization and Physicochemical Property of a Purified Fucosylated Glycosaminoglycan Sulfate From Holothuria leucospilota

open access: yeseFood, Volume 6, Issue 4, August 2025.
(1) The main chain structure of Holothuria leucospilota polysaccharides (HLP‐Ⅰ) was presumed to be roughly as →3)‐β‐d‐GalpNAc‐(1→4)‐β‐d‐GlcpA‐(1→. (2) with T‐Fucp on the branched chain or a rockulose chain consisting of →3,4)‐α‐l‐Fucp‐(1→. (3) HLP‐Ⅰ showed high amorphous platelet content and disordered arrangement, while the molecule adapted a sphere ...
Wanting Wang   +7 more
wiley   +1 more source

Carrageenans from Red Seaweeds As Promoters of Growth and Elicitors of Defense Response in Plants [PDF]

open access: yes, 2016
Plants incessantly encounter abiotic and biotic stresses that limit their growth and productivity. However, conversely, plant growth can also be induced by treatments with various abiotic and biotic elicitors.
Alan T. Critchley   +3 more
core   +2 more sources

Fucoidan From Brown Algae as a Functional Food Ingredient: A Promising Anticancer Agent

open access: yeseFood, Volume 6, Issue 4, August 2025.
Fucoidan, a bioactive polysaccharide from brown algae, inhibits receptor tyrosine kinase (RTK) activation and vascular endothelial growth factor (VEGF) signaling, suppressing the phosphoinositide 3‐kinase/protein kinase B/mammalian target of rapamycin (PI3K/Akt/mTOR) and RAS/RAF/mitogen‐activated protein kinase/extracellular signal‐regulated kinase ...
Muhammad Umer Khan   +7 more
wiley   +1 more source

Simple Extraction and Molecular Weight Characterization of Fucoidan From Indonesian Sargassum SP. [PDF]

open access: yes, 2013
Fucoidan is a complex polysaccharide compounds found in brown algae. Fucoidan exhibits various biological properties for disease prevention. There are various methods used to extract fucoidan from brown algae, such as using ethanol, acetone, HCl and ...
Junaidi, L. (Lukman)
core   +1 more source

Home - About - Disclaimer - Privacy