Results 61 to 70 of about 1,407 (187)
Sulfatases: Catalytic Mechanism, Substrate Preferences, and Carbohydrate‐Based Inhibitor Design
Sulfatases are a class of enzymes that can cleave sulfates from heparan sulfate and modulate many of their biological activities. In this review, following a general introduction on sulfatase, their enzymatic mechanism and substrate scope are discussed.
Morgan Mayieka +3 more
wiley +1 more source
Algae as nutritional and functional food sources: revisiting our understanding. [PDF]
Global demand for macroalgal and microalgal foods is growing, and algae are increasingly being consumed for functional benefits beyond the traditional considerations of nutrition and health.
Wells, Mark L +8 more
core +9 more sources
Thromboembolic diseases are increasing worldwide and always require anticoagulant therapy. We still need safer and more secure antithrombotic drugs than those presently available. Sulfated polysaccharides from marine organisms may constitute a new source
Paulo A. S. Mourão
doaj +1 more source
(1) The main chain structure of Holothuria leucospilota polysaccharides (HLP‐Ⅰ) was presumed to be roughly as →3)‐β‐d‐GalpNAc‐(1→4)‐β‐d‐GlcpA‐(1→. (2) with T‐Fucp on the branched chain or a rockulose chain consisting of →3,4)‐α‐l‐Fucp‐(1→. (3) HLP‐Ⅰ showed high amorphous platelet content and disordered arrangement, while the molecule adapted a sphere ...
Wanting Wang +7 more
wiley +1 more source
Fucoidan From Brown Algae as a Functional Food Ingredient: A Promising Anticancer Agent
Fucoidan, a bioactive polysaccharide from brown algae, inhibits receptor tyrosine kinase (RTK) activation and vascular endothelial growth factor (VEGF) signaling, suppressing the phosphoinositide 3‐kinase/protein kinase B/mammalian target of rapamycin (PI3K/Akt/mTOR) and RAS/RAF/mitogen‐activated protein kinase/extracellular signal‐regulated kinase ...
Muhammad Umer Khan +7 more
wiley +1 more source
Some antioxidant compounds decrease the amount of intracellular reactive oxygen species (ROS) and consequently reduce the deleterious effects of ROS in osteoblasts. Thus, these compounds fight against osteoporosis.
Gabriel Pereira Fidelis +5 more
doaj +1 more source
Identification and evaluation of fungal strains with fucoidan degradation potential [PDF]
Ten fungal strains isolated of Mexican semi-desert were screened for ability to hydrolyze fucoidan in order to search microorganism capable to produce sulfated fucans-degrading enzymes.
Aguilar Gonzalez, Cristobal Noé +3 more
core
Anti-proliferation Potential and Content of Fucoidan Extracted From Sporophyll of New Zealand Undaria Pinnatifida [PDF]
Undaria pinnatifida is a species of brown seaweed known to contain rich amounts of fucoidan, a sulfated polysaccharide known to possess various biological activities. We isolated crude fucoidan (F0) from the sporophylls of U.
Hamid, N +6 more
core +1 more source
The specificity of interactions between proteins and sulfated polysaccharides
Sulfated polysaccharides are capable of binding with proteins at several levels of specificity. As highly acidic macromolecules, they can bind non-specifically to any basic patch on a protein surface at low ionic strength, and such interactions are not ...
Barbara Mulloy
doaj +1 more source
Horizontal gene transfer contributed to the evolution of extracellular surface structures [PDF]
The single-cell layered ectoderm of the fresh water polyp Hydra fulfills the function of an epidermis by protecting the animals from the surrounding medium.
Altstätter, Johannes +13 more
core +1 more source

