Results 61 to 70 of about 1,407 (187)

Sulfatases: Catalytic Mechanism, Substrate Preferences, and Carbohydrate‐Based Inhibitor Design

open access: yesIsrael Journal of Chemistry, Volume 65, Issue 12, December 2025.
Sulfatases are a class of enzymes that can cleave sulfates from heparan sulfate and modulate many of their biological activities. In this review, following a general introduction on sulfatase, their enzymatic mechanism and substrate scope are discussed.
Morgan Mayieka   +3 more
wiley   +1 more source

Algae as nutritional and functional food sources: revisiting our understanding. [PDF]

open access: yes, 2017
Global demand for macroalgal and microalgal foods is growing, and algae are increasingly being consumed for functional benefits beyond the traditional considerations of nutrition and health.
Wells, Mark L   +8 more
core   +9 more sources

Perspective on the Use of Sulfated Polysaccharides from Marine Organisms as a Source of New Antithrombotic Drugs

open access: yesMarine Drugs, 2015
Thromboembolic diseases are increasing worldwide and always require anticoagulant therapy. We still need safer and more secure antithrombotic drugs than those presently available. Sulfated polysaccharides from marine organisms may constitute a new source
Paulo A. S. Mourão
doaj   +1 more source

Structural Characterization and Physicochemical Property of a Purified Fucosylated Glycosaminoglycan Sulfate From Holothuria leucospilota

open access: yeseFood, Volume 6, Issue 4, August 2025.
(1) The main chain structure of Holothuria leucospilota polysaccharides (HLP‐Ⅰ) was presumed to be roughly as →3)‐β‐d‐GalpNAc‐(1→4)‐β‐d‐GlcpA‐(1→. (2) with T‐Fucp on the branched chain or a rockulose chain consisting of →3,4)‐α‐l‐Fucp‐(1→. (3) HLP‐Ⅰ showed high amorphous platelet content and disordered arrangement, while the molecule adapted a sphere ...
Wanting Wang   +7 more
wiley   +1 more source

Fucoidan From Brown Algae as a Functional Food Ingredient: A Promising Anticancer Agent

open access: yeseFood, Volume 6, Issue 4, August 2025.
Fucoidan, a bioactive polysaccharide from brown algae, inhibits receptor tyrosine kinase (RTK) activation and vascular endothelial growth factor (VEGF) signaling, suppressing the phosphoinositide 3‐kinase/protein kinase B/mammalian target of rapamycin (PI3K/Akt/mTOR) and RAS/RAF/mitogen‐activated protein kinase/extracellular signal‐regulated kinase ...
Muhammad Umer Khan   +7 more
wiley   +1 more source

Antioxidant Fucoidans Obtained from Tropical Seaweed Protect Pre-Osteoblastic Cells from Hydrogen Peroxide-Induced Damage

open access: yesMarine Drugs, 2019
Some antioxidant compounds decrease the amount of intracellular reactive oxygen species (ROS) and consequently reduce the deleterious effects of ROS in osteoblasts. Thus, these compounds fight against osteoporosis.
Gabriel Pereira Fidelis   +5 more
doaj   +1 more source

Identification and evaluation of fungal strains with fucoidan degradation potential [PDF]

open access: yes, 2008
Ten fungal strains isolated of Mexican semi-desert were screened for ability to hydrolyze fucoidan in order to search microorganism capable to produce sulfated fucans-degrading enzymes.
Aguilar Gonzalez, Cristobal Noé   +3 more
core  

Anti-proliferation Potential and Content of Fucoidan Extracted From Sporophyll of New Zealand Undaria Pinnatifida [PDF]

open access: yes, 2014
Undaria pinnatifida is a species of brown seaweed known to contain rich amounts of fucoidan, a sulfated polysaccharide known to possess various biological activities. We isolated crude fucoidan (F0) from the sporophylls of U.
Hamid, N   +6 more
core   +1 more source

The specificity of interactions between proteins and sulfated polysaccharides

open access: yesAnais da Academia Brasileira de Ciências, 2005
Sulfated polysaccharides are capable of binding with proteins at several levels of specificity. As highly acidic macromolecules, they can bind non-specifically to any basic patch on a protein surface at low ionic strength, and such interactions are not ...
Barbara Mulloy
doaj   +1 more source

Horizontal gene transfer contributed to the evolution of extracellular surface structures [PDF]

open access: yes, 2012
The single-cell layered ectoderm of the fresh water polyp Hydra fulfills the function of an epidermis by protecting the animals from the surrounding medium.
Altstätter, Johannes   +13 more
core   +1 more source

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