Serum Sulfonylurea Receptor-1 Levels After Acute Supratentorial Intracerebral Hemorrhage: Implication for Prognosis [PDF]
Neuropsychiatric Disease and Treatment, 2022 Cheng-Jun Zhuge,1 Cheng-Peng Zhan,2 Ke-Wei Wang,1 Xin-Jiang Yan,2 Guo-Feng Yu2 1The Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China; 2Department of Neurosurgery, The Quzhou Affiliated Hospital
Zhuge CJ +4 more
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Myocardial protection by adenosine triphosphate−sensitive potassium channel opener diazoxide involves sulfonylurea receptor 2 subunitCentral MessagePerspective [PDF]
JTCVS OpenObjective: Pharmacologic openers of adenosine triphosphate-sensitive potassium (KATP) channels mimic ischemic preconditioning and are cardioprotective.
Jie Wang, MD +6 more
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aThe characteristics of glucose metabolism in the sulfonylurea receptor 1 knockout rat model [PDF]
Molecular Medicine, 2019 Background Sulfonylurea receptor 1 (SUR1) is primarily responsible for glucose regulation in normal conditions. Here, we sought to investigate the glucose metabolism characteristics of SUR1 −/− rats.
Xiaojun Zhou +7 more
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An endogenous ligand for the central sulfonylurea receptor [PDF]
FEBS Letters, 1988 An endogenous ligand for the rat central sulfonylurea receptor has been evidenced in the rat central nervous system. The characteristics of this ligand (extractibility, non‐dialysability, chromatographic behaviour on different media, sensitivity to proteases) indicate that it is a neutral to slightly basic peptide.
Annick Cauvin, D Bataille
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Sulfonylurea Receptor Pharmacology Alters the Performance of Two Central Pattern Generating Circuits in Cancer borealis [PDF]
FunctionNeuronal activity and energy supply must maintain a fine balance for neuronal fitness. Various channels of communication between the two could impact network output in different ways.
Sonal Kedia +3 more
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Myoprotective Fat-Loss Phenotypes in Obesity-Associated Type 2 Diabetes: A 12-Month Real-World Cohort Study of Metformin-Based Treatment Regimens [PDF]
Clinics and PracticeBackground/Objectives: In obesity-associated type 2 diabetes (T2DM), therapeutic benefit increasingly requires assessment of not only HbA1c and total body weight, but also the composition and functional quality of weight change.
Ioana Bujdei-Tebeică +4 more
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The ATPase activities of sulfonylurea receptor 2A and sulfonylurea receptor 2B are influenced by the C-terminal 42 amino acids [PDF]
FEBS Journal, 2010 Unusually among ATP‐binding cassette proteins, the sulfonylurea receptor (SUR) acts as a channel regulator. ATP‐sensitive potassium channels are octameric complexes composed of four pore‐forming Kir6.2 subunits and four regulatory SUR subunits. Two different genes encode SUR1 (ABCC8) and SUR2 (ABCC9), with the latter being differentially spliced to ...
Frances Ashcroft, Heidi de Wet
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Sulfonylurea Receptor 1 in Central Nervous System Injury: An Updated Review [PDF]
International Journal of Molecular Sciences, 2021 Joshua S Catapano, W Taylor Kimberly
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Sulfonylurea receptor 1 expression in human cerebral infarcts. [PDF]
J Neuropathol Exp Neurol, 2013 In animal models of stroke, sulfonylurea receptor 1 (Sur1), a member of the adenosine triphosphate binding cassette transporter gene family, is transcriptionally upregulated in neural and vascular cells in which it plays a leading role in edema formation and necrotic cell death. To date, expression of Sur1 in the brains of humans with cerebral infarcts
Mehta RI +5 more
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Biochimica Et Biophysica Acta - Molecular Cell Research, 1992 Frances Ashcroft +2 more
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