Results 171 to 180 of about 16,993 (221)

Antimetastatic activity of Sulforaphane

Life Sciences, 2006
The effect of Sulforaphane on the inhibition of lung metastasis induced by B16F-10 melanoma cells was studied in C57BL/6 mice by three different modalities of administration-simultaneous, prophylactic and after tumour developed. Of this simultaneous mode of Sulforaphane administration was found to be most effective.
P, Thejass, Girija, Kuttan
openaire   +2 more sources

Evolution of sulforaphane content in sulforaphane-enriched broccoli during tray drying

Journal of Food Engineering, 2016
Abstract Sulforaphane is a natural anticancer compound found in broccoli that comes from hydrolysis of glucoraphanin. Conversion of glucoraphanin to sulforaphane has been optimized, however, its use as functional ingredient is limited because sulforaphane is thermo-labile.
Andrea Mahn, Alejandro Reyes, Aldo F. Saavedra   +2 more
exaly   +2 more sources

Sulforaphane and prostate cancer interception

Drug Discovery Today, 2014
Whereas much attention is focused on distinguishing newly diagnosed prostate cancers that will progress to become aggressive forms of the disease from those that will remain indolent, it is also appropriate to explore therapeutic and lifestyle interventions to reduce the risk of progression.
Maria H, Traka, Antonietta, Melchini, Richard F, Mithen   +2 more
openaire   +2 more sources

Synergistic Effect of Combination of Phenethyl Isothiocyanate and Sulforaphane or Curcumin and Sulforaphane in the Inhibition of Inflammation

Pharmaceutical Research, 2008
Accumulating evidence from epidemiologic and clinical studies indicates that chronic inflammatory disorders harbor an increased risk of cancer development. Curcumin (CUR) has been strongly linked to the anti-inflammatory effect. On the other hand, isothiocyanates such as sulforaphane (SFN) and phenethyl isothiocyanate (PEITC) are strong phase-II ...
Ka Lung, Cheung, Tin Oo, Khor, Ah-Ng, Kong   +2 more
openaire   +2 more sources

Thermal Degradation of Sulforaphane in Aqueous Solution

Journal of Agricultural and Food Chemistry, 1999
Sulforaphane, a cancer chemopreventive agent identified from broccoli, was degraded in an aqueous solution at 50 and 100 degrees C. The reaction mixtures were extracted with methylene chloride and analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS).
Rosen, RT, Jin, Y, Wang, M, Ho, CT
openaire   +4 more sources

A new validated HPLC method for the determination of sulforaphane: application to study pharmacokinetics of sulforaphane in rats

Biomedical Chromatography, 2015
AbstractA simple, accurate and reproducible high‐performance liquid chromatography (HPLC) method has been developed and validated for the quantification of sulforaphane (SF) in rat plasma. The method involves a simple liquid–liquid extraction procedure to extract both SF and 7‐hyrdoxycoumarin, the internal standard.
Chau, Ong, Fawzy, Elbarbry
openaire   +2 more sources