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Broccoli or Sulforaphane: Is It the Source or Dose That Matters? [PDF]

open access: yesMolecules, 2019
There is robust epidemiological evidence for the beneficial effects of broccoli consumption on health, many of them clearly mediated by the isothiocyanate sulforaphane.
Jed W Fahey   +2 more
exaly   +4 more sources
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Antimetastatic activity of Sulforaphane

Life Sciences, 2006
The effect of Sulforaphane on the inhibition of lung metastasis induced by B16F-10 melanoma cells was studied in C57BL/6 mice by three different modalities of administration-simultaneous, prophylactic and after tumour developed. Of this simultaneous mode of Sulforaphane administration was found to be most effective.
P, Thejass, Girija, Kuttan
openaire   +2 more sources

Isothiocyanate from Broccoli, Sulforaphane, and Its Properties [PDF]

open access: yesJournal of Medicinal Food, 2019
Sulforaphane is an isothiocyanate occurring in stored form as glucoraphanin in cruciferous vegetables such as cabbage, cauliflower, and kale, and at high levels in broccoli especially in broccoli sprouts. Glucoraphanin requires the plant enzyme myrosinase for converting it into sulforaphane. Sulforaphane is metabolized through mercapturic acid pathway,
Eva Anzenbacherová
exaly   +3 more sources

Sulforaphane and prostate cancer interception

Drug Discovery Today, 2014
Whereas much attention is focused on distinguishing newly diagnosed prostate cancers that will progress to become aggressive forms of the disease from those that will remain indolent, it is also appropriate to explore therapeutic and lifestyle interventions to reduce the risk of progression.
Maria H, Traka   +2 more
openaire   +2 more sources

Evolution of sulforaphane content in sulforaphane-enriched broccoli during tray drying

Journal of Food Engineering, 2016
Abstract Sulforaphane is a natural anticancer compound found in broccoli that comes from hydrolysis of glucoraphanin. Conversion of glucoraphanin to sulforaphane has been optimized, however, its use as functional ingredient is limited because sulforaphane is thermo-labile.
Andrea Mahn   +3 more
openaire   +1 more source

Sulforaphane Induces Glioprotection After LPS Challenge

Cellular and Molecular Neurobiology, 2020
Sulforaphane is a natural compound that presents anti-inflammatory and antioxidant properties, including in the central nervous system (CNS). Astroglial cells are involved in several functions to maintain brain homeostasis, actively participating in the inflammatory response and antioxidant defense systems.
Larissa Daniele Bobermin   +6 more
openaire   +2 more sources

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