Transient Sulfenic Acids in the Synthesis of Biologically Relevant Products
Molecules, 2018 Sulfenic acids as small molecules are too unstable to be isolated and their transient nature offers the possibility to involve them in concerted processes that lead to the obtainment of functional groups such as sulfoxides, sulfones, and disulfides.
Anna Barattucci +4 more
doaj +1 more source
Pinacol as a new green reducing agent: molybdenum-catalyzed chemoselective reduction of sulfoxides and nitroaromatics [PDF]
, 2012 Pinacol is disclosed as a new chemoselective and environmentally benign reducing agent for sulfoxides and nitroaromatics assisted by readily available dichlorodioxomolybdenum(VI) complexes as catalysts.
Arnáiz García, Francisco Javier +6 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molybdenum-catalyzed enantioselective sulfoxidation controlled by a nonclassical hydrogen bond between coordinated chiral imidazolium-based dicarboxylate and peroxido ligands [PDF]
, 2018 Chiral alkyl aryl sulfoxides were obtained by molybdenum-catalyzed oxidation of alkyl aryl sulfides with hydrogen peroxide as oxidant in mild conditions with high yields and moderate enantioselectivities.
Carrasco Carrasco, Carlos Jesús +2 more
core
Metal-organic frameworks as selective or chiral oxidation catalysts [PDF]
, 2014 Since the discovery of Metal Organic Frameworks (MOFs) in the early 1990s, the amount of new structures has grown exponentially. A MOF typically consists of inorganic nodes that are connected by organic linkers to form crystalline, highly porous ...
Leus, Karen +2 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Photocatalytic formation of carbon–sulfur bonds
Beilstein Journal of Organic Chemistry, 2018 This review summarizes recent developments in photocatalyzed carbon–sulfur bond formation. General concepts, synthetic strategies and the substrate scope of reactions yielding thiols, disulfides, sulfoxides, sulfones and other organosulfur compounds are ...
Alexander Wimmer, Burkhard König
doaj +1 more source
Aetiology and treatment of epidermal depigmentory disorder in humans [PDF]
, 2012 The epidermal depigmentary trigger in humans at post-natal level may occur with the toxification of skin organ with the endogenously produced melanocytotoxic hydrogen peroxide and subsequent formation of hydrogen peroxide- melanolipoprotein conjugate ...
S. S. Sawhney
core +1 more source
Green process for adipic acid synthesis: oxidation by hydrogen peroxide in water micromelusions using Benzalkonium Chloride C12-14 surfactant [PDF]
, 2012 Adipic acid was synthesized by the oxidation of cyclohexene using 30% hydrogen peroxide in a microemulsion in the presence of sodium tungstate as catalyst.
Cognet, Patrick +3 more
core +3 more sources
Benzyl 2-ethylhexyl sulfoxide [PDF]
Acta Crystallographica Section E Structure Reports Online, 2009 The mol-ecule of the title compound, C(15)H(24)OS, shows S conformations for the S atom and the asymmetric C atom of the isooctyl group. The long axes of the mol-ecules are directed along the c axis. In the crystal structure, the mol-ecules are linked by weak inter-molecular bifurcated C-H⋯O hydrogen bonds.
Xu Zhi-Guang +4 more
openaire +3 more sources