Results 11 to 20 of about 21,065 (189)
Staphylococcal Enterotoxin A Shapes Monocyte Transcription and Macrophage Polarization: Implications for Immune Responses in Infection and Inflammation. [PDF]
Eur J ImmunolStaphylococcal enterotoxin A (SEA) alters monocyte differentiation and function, while preserving T cell stimulatory capacity. SEA‐primed macrophages downregulate antigen‐presenting markers yet drive heightened T‐cell proliferation and IFN‐γ secretion.
Arasa C +4 more
europepmc +2 more sources
Frontiers in Microbiology, 2022 Enterotoxins (SEs) produced by Staphylococcus aureus are the cause of serious food intoxications. Staphylococcal enterotoxin C (SEC) is one of the main contributors, as it is often highly expressed. S. aureus possesses a competitive growth advantage over
Danai Etter +5 more
doaj +1 more source
Experimental Dermatology, 1996 Abstract Superantigens are potent modulators of the immune system. Some of their biological and immunological properties are reviewed here with special attention to their potential significance for cutaneous inflammation, specific skin immune responses and skin diseases.
J, Saloga, E W, Gelfand, J, Knop
openaire +2 more sources
Antigen-specific downregulation of miR-150 in CD4 T cells promotes cell survival
Frontiers in Immunology, 2023 MicroRNA-150 (miR-150) has been shown to play a general role in the immune system, but very little is known about its role on CD4+ T cell responses. During T cell responses against superantigen Staphylococcal Enterotoxin A, miR-150 expression was down ...
Antoine Ménoret +5 more
doaj +1 more source
PLoS ONE, 2021 BackgroundMethicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant (MDR) S. aureus strains are well recognized as posing substantial problems in treating ocular infections. S.
Min Lu, Jean-Marie Parel, Darlene Miller
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陆军军医大学学报, 2023 As of November 2022, 22 countries in Europe have reported 572 cases of severe acute hepatitis in children with unknown causes. The most common pathogens tested are human adenovirus and SARS-CoV-2. Therefore, the researchers have proposed hypotheses about
DENG Guohong, SHI Tuo
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Frontiers in Immunology, 2022 Multisystem inflammatory syndrome in children (MIS-C) is a febrile pediatric inflammatory disease that may develop weeks after initial SARS-CoV-2 infection or exposure.
Magali Noval Rivas +8 more
doaj +1 more source
Interference of the T cell and antigen-presenting cell costimulatory pathway using CTLA4-Ig (abatacept) prevents Staphylococcal enterotoxin B pathology [PDF]
, 2017 Staphylococcal enterotoxin B (SEB) is a bacterial superantigen that binds the receptors in the APC/T cell synapse and causes increased proliferation of T cells and a cytokine storm syndrome in vivo.
Carter, Alun J +10 more
core +2 more sources
T cell activation or tolerization: the Yin and Yang of bacterial superantigens
Frontiers in Microbiology, 2015 Bacterial superantigens are exotoxins from pathogens which interact with innate and adaptive immune cells. The paradox that superantigens cause activation and inactivation/anergy of T-cells was soon recognized.
Aline eSähr +3 more
doaj +1 more source
Staphylococcus aureus enterotoxin B regulates prostaglandin E-2 synthesis, growth, and migration in nasal tissue fibroblasts [PDF]
, 2008 Background. Superantigens and eicosanoids are important amplifiers and regulators of inflammation in airway diseases. We therefore studied the possible influence of Staphylococcus aureus enterotoxin B ( SEB) on the cyclooxygenase ( COX) pathway and basic
Bachert, Claus +4 more
core +2 more sources