Results 91 to 100 of about 22,006 (218)

DNA supercoiling and transcription in bacteria: a two-way street

open access: yesBMC Molecular and Cell Biology, 2019
Background The processes of DNA supercoiling and transcription are interdependent because the movement of a transcription elongation complex simultaneously induces under- and overwinding of the DNA duplex and because the initiation, elongation and ...
Charles J. Dorman
doaj   +1 more source

Chromosome segregation in a minimal bacterial cell driven by SMC protein complexes

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Minimal bacterial cells such as JCVI‐Syn3A provide a powerful system for uncovering the essential mechanisms of chromosome organization and segregation. Lacking canonical systems such as Min and ParABS, JCVI‐Syn3A relies primarily on structural maintenance of chromosomes (SMC) protein complexes for partitioning.
Andrew K. Maytin   +2 more
wiley   +1 more source

The physics of epigenetics

open access: yes, 2016
In higher organisms, all cells share the same genome, but every cell expresses only a limited and specific set of genes that defines the cell type. During cell division, not only the genome, but also the cell type is inherited by the daughter cells. This
Barbi, Maria   +6 more
core   +3 more sources

Characterizing the Impact of Nucleoid‐Associated Proteins on HU‐DNA Interactions by Live‐Cell Single‐Molecule Tracking

open access: yesChemPhysChem, Volume 27, Issue 9, 14 May 2026.
The nucleoid‐associated proteins Dps, H‐NS, and HU shape the bacterial chromosome in the deep stationary phase through their interactions with the nucleoid.The bacterial nucleoid undergoes extensive structural reorganization during growth, influenced by nucleoid‐associated proteins (NAPs) whose interactions and effects on nucleoid organization remain ...
D. E. H. Fuller   +5 more
wiley   +1 more source

Elastic Rod Model of a Supercoiled DNA Molecule

open access: yes, 2000
We study the elastic behaviour of a supercoiled DNA molecule. The simplest model is that of a rod like chain, involving two elastic constants, the bending and the twist rigidities.
Bouchiat, Claude, Mezard, Marc
core   +2 more sources

Immortalization of Human Adult Alveolar Epithelial Cells to Study Environmental Exposures of the Distal Lung

open access: yesCurrent Protocols, Volume 6, Issue 5, May 2026.
Abstract Alveolar epithelial cell type 1 (AT1) and type 2 (AT2) cells make up the saccular gas exchange units of the lung, called alveoli. Formation of alveoli during lung development accounts for the expansive surface area of the lung, allowing for proper respiration and delivery of oxygen to the body.
Evelyn Tran   +11 more
wiley   +1 more source

Evolution, Adaptation, and Supercoiling [PDF]

open access: yesJournal of Bacteriology, 2007
Geometrical and, to some extent, physical and informational properties of covalently closed DNA molecules (or molecules that can be ideally viewed as closed) are determined by their connectivity, i.e., the number of times one strand of DNA is topologically linked to another.
openaire   +2 more sources

The mechanisms responsible for 2-dimensional pattern formation in bacterial macrofiber populations grown on solid surfaces: fiber joining and the creation of exclusion zones

open access: yesBMC Microbiology, 2002
Background When Bacillus subtilis is cultured in a complex fluid medium under conditions where cell separation is suppressed, populations of multicellular macrofibers arise that mature into ball-like structures.
Morales David   +2 more
doaj   +1 more source

Ferrocene‐Based Sensors for Green Analytical Applications in Environmental, Biomedical, Industrial, and Food Monitoring

open access: yesChemistryOpen, Volume 15, Issue 5, May 2026.
Ferrocene derivatives represent a transformative class of molecular sensors, combining exceptional electrochemical stability with tunable redox characteristics that enable precise detection across diverse analytical challenges in environmental, medical, and industrial applications.
Ala'a Al‐Akhras   +6 more
wiley   +1 more source

Supercoiling in DNA and chromatin

open access: yesCurrent Opinion in Genetics & Development, 2014
Supercoiling is a fundamental property of DNA and chromatin. It is modulated by polymerase and topoisomerase activities and, through regulated constraint, by DNA/chromatin binding proteins. As a non-covalent and elusive topological modification, supercoiling has proved intractable to research despite being a crucial regulator of nuclear structure and ...
Gilbert, N., Allan, J.
openaire   +3 more sources

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