Results 41 to 50 of about 8,443,769 (248)

Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea

Frontiers in Cellular Neuroscience, 2015
Sensorineural hearing loss is most commonly caused by the death of hair cells in the organ of Corti, and once lost, mammalian hair cells do not regenerate. In contrast, other vertebrates such as birds can regenerate hair cells by stimulating division and
Juan Cristobal Maass, Juan Cristobal Maass, Juan Cristobal Maass, Rende eGu, Martin L. Basch, Joerg eWaldhaus, Eduardo eMartin-Lopez, Anping eXia, John S. Oghalai, Stefan eHeller, Andrew K. Groves, Andrew K. Groves, Andrew K. Groves   +12 more
doaj   +1 more source

Elevated O-GlcNAc levels activate epigenetically repressed genes and delay mouse ES cell differentiation without affecting naïve to primed cell transition [PDF]

, 2014
The differentiation of mouse embryonic stem (ES) cells is controlled by the interaction of multiple signaling pathways, typically mediated by post-translational protein modifications.
Speakman, Christopher M., Stavridis, Marios P., Domke, Tanja C. E., Stavridis, Marios P. ; id_orcid, van Aalten, Daan M. F., Barton, Geoffrey J.; id_orcid, Sanders, Kelly, Wongpaiboonwattana, Wikrom, van Aalten, Daan M.F., Mudaliar, Manikhandan, Barton, Geoffrey J., Domke, Tanja C.E.   +11 more
core   +1 more source

Restrictions in cell cycle progression of adult vestibular supporting cells in response to ectopic cyclin D1 expression. [PDF]

PLoS ONE, 2011
Sensory hair cells and supporting cells of the mammalian inner ear are quiescent cells, which do not regenerate. In contrast, non-mammalian supporting cells have the ability to re-enter the cell cycle and produce replacement hair cells.
Heidi Loponen, Jukka Ylikoski, Jeffrey H Albrecht, Ulla Pirvola   +3 more
doaj   +1 more source

Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics

Nature Communications, 2022
Here, the authors use single cell RNA-sequencing to generate an atlas of signaling interactions regulating embryonic hematopoietic stem cell (HSC) development and apply this knowledge to engineer a niche sufficient to support HSC maturation in vitro.
Brandon Hadland, Barbara Varnum-Finney, Stacey Dozono, Tessa Dignum, Cynthia Nourigat-McKay, Adam M. Heck, Takashi Ishida, Dana L. Jackson, Tomer Itkin, Jason M. Butler, Shahin Rafii, Cole Trapnell, Irwin D. Bernstein   +12 more
doaj   +1 more source

Caring Process in Hematopoietic Stem Cell Transplantation: A Grounded Theory Study

International Journal of Hematology-Oncology and Stem Cell Research, 2019
Background: Caring is one of the main concepts in nursing and its modes of delivery in different diseases have been widely studied. Hematopoietic Stem Cell Transplantation (HSCT) is a novel, complex, and time-consuming clinical intervention which is ...
Leila Sayadi, Vahid Zamanzadeh, Leila Valizadeh, Fariba Taleghani   +3 more
doaj   +1 more source

Supporting information for PhD thesis

, 2023
The supporting Information of this doctoral thesis is divided in the Supporting Information (PDF) and a Data package. The supporting information contains all the supplementary figures and tables of the spectroscopic, crystallographic and computational ...
Cody B. van Beek-Hagemans (Utrecht University)
core   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Management of giant-cell arteritis in Switzerland: an online national survey [PDF]

, 2023
AIMS OF THE STUDY: To assess current practices in diagnosing, treating, and following-up giant-cell arteritis by specialists in Switzerland and to identify the main barriers to using diagnostic tools.
Diana Dan, Courvoisier, Delphine, Thomas Daikeler, Dan, Diana, Mahr, Alfred, Daikeler, Thomas, Christoph T. Berger, Stegert, Mihaela, Alfred Mahr, Iudici, Michele, Berger, Christoph T, Villiger, Peter, Wildi, Lukas, Thomas Neumann, Neumann, Thomas, Mike Oliver Becker, Lukas Wildi, Seitz, Luca, Andrea Katharina Hemmig, Giant Cell Arteritis SCQM Study Group, Sabine Adler, Ribi, Camillo, Finckh, Axel, Axel Finckh, Luca Seitz, Berger, Christoph T., Courvoisier, Courvoisier, Mihaela Stegert, Stephan Reichenbach, Peter Villiger, Adler, Sabine, Michele Iudici, Becker, Mike Oliver, Courvoisier Courvoisier, on behalf of Giant Cell Arteritis SCQM Study Group, Reichenbach, Stephan, Camillo Ribi, Hemmig, Andrea Katharina, Berger, C.T., Iudici, M., Becker, M.O., Adler, S., Hemmig, A.K., Dan, D., Wildi, L., Villiger, P., Ribi, C., Stegert, M., Neumann, T., Daikeler, T., Seitz, L., Finckh, A., Reichenbach, S., Mahr, A., Courvoisier, D.S.   +54 more
core   +2 more sources

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Histomorphometric study of testis in deltamethrin treated albino rats

Toxicology Reports, 2014
Deltamethrin, a type II synthetic pyrethroid, has lead to a widespread concern over the potential adverse effects on human health. Adult Wistar albino rats, weighing 150–200 g, were divided into two groups of ten animals each.
Anil Kumar, Mahindra Nagar
doaj   +1 more source