Results 251 to 260 of about 574,337 (298)
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Drug Development and Industrial Pharmacy, 1988
AbstractBy grinding, chloramphenicol stearate Form III turns into Form I: then this form tends to become amorphous. So the grinding of both forms produces a “physically activated” form (FI*) with low crystallinity degree and high CAP availability.
FORNI, Flavio +4 more
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AbstractBy grinding, chloramphenicol stearate Form III turns into Form I: then this form tends to become amorphous. So the grinding of both forms produces a “physically activated” form (FI*) with low crystallinity degree and high CAP availability.
FORNI, Flavio +4 more
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Surfaces and Interfaces, 2020
Abstract The surface of dispersed systems in which the dispersion medium is solid presents a complex morphology that depends on the processes associated with the formation of the solid phase and the dispersion grade of the dispersed phase. Considering that this morphology is a manifestation of the stochastic processes in the disperse phase, a ...
Edgardo J. Suarez-Dominguez +4 more
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Abstract The surface of dispersed systems in which the dispersion medium is solid presents a complex morphology that depends on the processes associated with the formation of the solid phase and the dispersion grade of the dispersed phase. Considering that this morphology is a manifestation of the stochastic processes in the disperse phase, a ...
Edgardo J. Suarez-Dominguez +4 more
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Development of Nifedipine Amorphous Solid Dispersion Composed of Surface-Active Agents
Key Engineering Materials, 2021The amorphous solid dispersions (ASDs) containing amino methacrylate copolymer and surface-active agents were prepared to improve the nifedipine (NDP) dissolution. The different types of surface-active agent i.e., polysorbates 80, sodium lauryl sulfate (SLS) and polyethylene glycol (PEG) 400 were used. In order to evaluate the ASDs formulation,powder X-
Sukannika Tubtimsri, Yotsanan Weerapol
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Surface composition and contact angle relationships for differently prepared solid dispersions
European Journal of Pharmaceutics and Biopharmaceutics, 2008Solid dispersions are promising drug delivery forms which offer the possibility to disperse a hydrophobic drug in a hydrophilic matrix and thereby improve the dissolution behavior and the bioavailability of the drug. One important aspect and a prerequisite in understanding the drug dissolution mechanism from solid dispersions is a better analytical ...
Carina, Dahlberg +2 more
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Comparison of surface modification and solid dispersion techniques for drug dissolution
International Journal of Pharmaceutics, 2000Surface modification and solid dispersion formulations using hydrophilic excipients can significantly alter the dissolution behaviour of hydrophobic drug materials. The effect of these techniques used individually and in combination on the dissolution properties of the hydrophobic drug, phenylbutazone (PB), are compared. PB was treated with a poloxamer,
C, Rouchotas, O E, Cassidy, G, Rowley
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Exact surface-plasmon dispersion relation for spatially dispersive solid with an abrupt surface
Vacuum, 1997Abstract The exact surface-plasmon dispersion relation for a semi-infinite medium with an abrupt surface and an arbitrary wave-vector and frequency dependent dielectric function ϵ(q,ω) is obtained. The result is applied to the models with hydrodynamic and Lindhard dielectric functions and the comparison with other theories and the experiment is ...
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Dispersion-Polar Surface Tension Properties of Organic Solids
The Journal of Adhesion, 1970ABSTRACT A new definition for work of adhesion Wa is applied to computationally define the dispersion γs d and polar γs d components of the solid surface tension γs = γs d + γs d for twenty-five low energy substrates. These calculated surface properties are correlated with surface composition and structure.
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Surface Roughness Effects with Solid Lubricants Dispersed in Mineral Oils
A S L E Transactions, 1984The lubricating effectiveness of solid-lubricant dispersions are investigated in both point and line contacts using surfaces with both random and directional roughness characteristics. Friction and wear data obtained at relatively low speeds and at room temperature, indicate that the existence of solid lubricants such as graphite, MoS2, and PTFE in a ...
C. Cusano, P. R. Goglia, H. E. Sliney
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A novel surface-attached carvedilol solid dispersion with enhanced solubility and dissolution
Archives of Pharmacal Research, 2013A novel surface-attached, spray-dried solid dispersion containing poorly water-soluble carvedilol (CV) without any change in the crystallinity was prepared using water, polyvinylpyrrolidone (PVP K30) and Tween 80. The solid dispersion was optimized by investigating the effects of the weight ratios of Tween 80/PVP K30 and carrier/drug on the aqueous ...
Lee, Sung Neung +10 more
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Photonic Control of Surface Anchoring on Solid Colloids Dispersed in Liquid Crystals
Langmuir, 2011The anchoring of liquid-crystal (LC) mesogens to the surfaces of colloids is an important factor in determining intercolloidal interactions and the symmetry of the ensuing colloidal assembly in nematic colloids. The dynamic control of surface anchoring could therefore provide a handle to tune the colloidal organization and resulting properties in these
Chandran, S. Prathap +4 more
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