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Solid Fluctuations and Dispersion in Liquid-Solid Fluidized Beds With Low Surface Tension Media
ASME-JSME-KSME 2011 Joint Fluids Engineering Conference: Volume 1, Symposia – Parts A, B, C, and D, 2011Fluctuations and dispersion of solid particles were investigated in a liquid-solid fluidized bed of which diameter was 0.102 m and 2.5 m in height. Effects of liquid velocity (0.005 ∼ 0.13 m/s), particle size (0.5 ∼ 3.0 × 10−3 m) and surface tension of continuous liquid media (56 ∼ 72 × 10−3 N/m) on the fluctuation frequency and dispersion coefficient ...
H. O. Lim, M. J. Seo, Y. Kang, K. W. Jun
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Enhancement of the Ionic Conductivity in Solid‐Solid‐Dispersions by Surface Induced Defects
Berichte der Bunsengesellschaft für physikalische Chemie, 1984AbstractThe finding that dispersions of insulators such as alumina or silica in ionic conductors may exhibit considerably enhanced ionic conductivities compared to the pure material, has become a promising topic for optimizing the electric properties in solid state research.
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The effect of processing on the surface physical stability of amorphous solid dispersions
European Journal of Pharmaceutics and Biopharmaceutics, 2014The focus of this study was to investigate the effect of processing on the surface crystallization of amorphous molecular dispersions and gain insight into the mechanisms underpinning this effect. The model systems, amorphous molecular dispersions of felodipine-EUDRAGIT® E PO, were processed both using spin coating (an ultra-fast solvent evaporation ...
Qi, Sheng +5 more
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Analytical Chemistry, 2008
The combination of dispersive solid phase extraction (DSPE) and attenuated total reflection (ATR) infrared spectroscopy is presented using the joint determination of sorbic and benzoic acids in juice samples as a model analytical problem. The dispersive extraction process allows the selective extraction of the target analytes from the sample matrix ...
M C, Alcudia-León +3 more
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The combination of dispersive solid phase extraction (DSPE) and attenuated total reflection (ATR) infrared spectroscopy is presented using the joint determination of sorbic and benzoic acids in juice samples as a model analytical problem. The dispersive extraction process allows the selective extraction of the target analytes from the sample matrix ...
M C, Alcudia-León +3 more
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Pharmaceutical Development and Technology, 2019
The purpose of this research was to develop a novel revaprazan-loaded surface-modified solid dispersion (SMSD) with improved drug solubility and oral bioavailability. The impact of carriers on aqueous solubility of revaprazan was investigated. HPMC and Cremophor A25 were selected as an appropriate polymer and surfactant, respectively, due to their high
Jong Hyuck Park +10 more
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The purpose of this research was to develop a novel revaprazan-loaded surface-modified solid dispersion (SMSD) with improved drug solubility and oral bioavailability. The impact of carriers on aqueous solubility of revaprazan was investigated. HPMC and Cremophor A25 were selected as an appropriate polymer and surfactant, respectively, due to their high
Jong Hyuck Park +10 more
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ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
W.G. Schmidt +5 more
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AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
W.G. Schmidt +5 more
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A surface-immobilized model compound investigation of catalytic reactions in dispersed solids
Energy & Fuels, 1993Reactions of the silica-immobilized model compounds, ≃Ph(CH 2 ) n Ph(n = 1, 3, 4) and ≃PhCH 2 CH 2 OPh, with dispersed acid catalysts have been studied at 310-375 °C in the solid state. Reactions of these model compounds in the presence of a small particle size (15 nm) silica-1% alumina catalyst yield products typically expected for acid-catalyzed ...
A. C. Buchanan +3 more
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Wetting of Solids by Surface Active Agents: Dispersion and the Polar Surface Tension Components
1986Wetting of solids bу various surfactant solutions was investigated by the contact angle measurements. The results were analyzed using an approximation that the surfactant solutions have intrinsic dispersion (D) and polar (P) surface forces, analogous to solids and pure liquids. Using this approach gave the same value for the solid surface tension (i. e.
K. S. Birdi, E. H. Stenby
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Surface Enrichment and Depletion of the Active Ingredient in Spray Dried Amorphous Solid Dispersions
Pharmaceutical Research, 2018To study the effects of physicochemical properties of drug and polymer, as well as the drug-polymer interactions, on the surface composition of SDDs.Ethanol solutions containing a model drug (IMC, NMP or FCZ) and a model polymer (PVPK12, PVPK30 or PVP-VA) were spray dried, and the surface composition of SDDs was analyzed by XPS. The surface tensions of
Zhen, Chen +5 more
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Pharmaceutical Research, 2014
To identify molecular indicators of bulk and surface instabilities of amorphous dispersions prepared by hot melt extrusion.Four model drugs with different physicochemical properties were formulated with EUDRAGIT(®) E PO using hot melt extrusion. Samples were aged under a range of conditions for up to 6 months and characterized using SEM, ATR-FTIR, PXRD
Yang, Ziyi +4 more
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To identify molecular indicators of bulk and surface instabilities of amorphous dispersions prepared by hot melt extrusion.Four model drugs with different physicochemical properties were formulated with EUDRAGIT(®) E PO using hot melt extrusion. Samples were aged under a range of conditions for up to 6 months and characterized using SEM, ATR-FTIR, PXRD
Yang, Ziyi +4 more
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