Surfactant Protein D in Respiratory and Non-Respiratory Diseases
Frontiers in Medicine, 2018 Surfactant protein D (SP-D) is a multimeric collectin that is involved in innate immune defense and expressed in pulmonary, as well as non-pulmonary, epithelia.
Grith L. Sorensen
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Surfactant Protein-D and Asthma [PDF]
Chest, 2016 Much of the recent research in asthma has focused on delineating the causative factors that contribute to the pathobiology of both airway eosinophilia and neutrophilia, and steroid-refractory disease. The distal airway, once thought to be a sterile environment, is now known to be a complex arena of microorganisms, termed the lung microbiome ...
Mitchell, Patrick, O'Byrne, Paul
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Protective Role of Surfactant Protein D in Ocular Staphylococcus aureus Infection. [PDF]
PLoS ONE, 2015 Staphylococcus aureus is one of the most common pathogens causing keratitis. Surfactant protein D (SP-D) plays a critical role in host defense and innate immunity. In order to investigate the role of SP-D in ocular S.
Zhiyong Zhang +3 more
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Pathological Significance and Prognostic Value of Surfactant Protein D in Cancer
Frontiers in Immunology, 2018 Surfactant protein D (SP-D) is a pattern recognition molecule belonging to the Collectin (collagen-containing C-type lectin) family that has pulmonary as well as extra-pulmonary existence.
Alessandro Mangogna +11 more
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Surfactant protein D (SP-D) as a biomarker of SARS-CoV-2 infection. [PDF]
Clin Chim Acta, 2022 Background Surfactant protein-D (SP-D) is a lung-resident protein that has emerged as a potential biomarker for COVID-19. Previous investigations on acute respiratory distress syndrome patients demonstrated a significant increment of SP-D serum levels in
Salvioni L +11 more
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Surfactant protein D inhibits lipid-laden foamy macrophages and lung inflammation in chronic obstructive pulmonary disease. [PDF]
Cell Mol Immunol, 2023 Hsieh MH +12 more
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Serum surfactant protein D in COVID-19 is elevated and correlated with disease severity. [PDF]
BMC Infect Dis, 2021 Background The serum surfactant protein D (SP-D) level is suggested to be a useful biomarker for acute lung injuries and acute respiratory distress syndrome.
Tong M +11 more
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Surfactant protein D and bronchopulmonary dysplasia: a new way to approach an old problem. [PDF]
Respir Res, 2021 Surfactant protein D (SP-D) is a collectin protein synthesized by alveolar type II cells in the lungs. SP-D participates in the innate immune defense of the lungs by helping to clear infectious pathogens and modulating the immune response. SP-D has shown
Arroyo R, Kingma PS.
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Surfactant proteins A and D: role in the pathogenesis of community-acquired pneumonia and possible predictive perspectives [PDF]
Терапевтический архив, 2020 Community-acquired pneumonia is one of the most common infectious diseases and remains one of the leading causes of death in this group of diseases. Studies of community-acquired pneumonia are extremely relevant for modern clinical practice.
O. S. Kharlamovа +3 more
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Frontiers in Bioengineering and Biotechnology, 2021 This work is focused on the potential use of pulmonary surfactant to deliver full-length recombinant human surfactant protein SP-D (rhSP-D) using the respiratory air-liquid interface as a shuttle.
Cristina García-Mouton +5 more
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