Results 21 to 30 of about 985,929 (323)
Сибирский научный медицинский журнал, 2023 Surfactant proteins SP-A and SP-D, which belong to the family of collagen-containing type C lectins, are used as diagnostic and prognostic markers for many acute and chronic respiratory diseases.
K. Yu. Nikolaev +4 more
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Surfactant protein A and surfactant protein D in health and disease [PDF]
American Journal of Physiology-Lung Cellular and Molecular Physiology, 1998 Surfactant protein (SP) A and SP-D are collagenous glycoproteins with multiple functions in the lung. Both of these proteins are calcium-dependent lectins and are structurally similar to mannose-binding protein and bovine conglutinin. Both form polyvalent multimeric structures for interactions with pathogens, cells, or other molecules.
R J, Mason, K, Greene, D R, Voelker
openaire +2 more sources
Frontiers in Immunology, 2021 Human SP-D is a potent innate immune molecule whose presence at pulmonary mucosal surfaces allows its role in immune surveillance against pathogens. Higher levels of serum SP-D have been reported in the patients with severe acute respiratory syndrome ...
Miao-Hsi Hsieh +8 more
semanticscholar +1 more source
Journal of Medical Virology, 2021 Coronavirus disease‐2019 (COVID‐19) is a respiratory disease whose clinical manifestation ranges from asymptomatic to severe respiratory failure. The purpose of this study was to investigate the place of serum surfactant‐D (SP‐D) and angiopoetin‐2 (Ang‐2)
H. Alay, Esra Laloğlu
semanticscholar +1 more source
Бюллетень сибирской медицины, 2020 Every year, about six million people die from tobacco use. Respiratory epithelium is the first line of defense against exogenous invasion, in particular, harmful inhaled particles, pathogens and allergens. However, the epithelium of the respiratory tract
O. S. Kharlamovа +3 more
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Association of SP-A and SP-D Surfactant Proteins with the Severity of CommunityAcquired Pneumonia
Неотложная медицинская помощь, 2020 Relevance. In current clinical practice, there is a need for research to find new diagnostic tests for the purpose of determining the patients with the highest risk of death from pneumonia.
O. S. Kharlamova +3 more
doaj +1 more source
The detection of surfactant proteins A, B, C and D in the human brain and their regulation in cerebral infarction, autoimmune conditions and infections of the CNS. [PDF]
PLoS ONE, 2013 Surfactant proteins (SP) have been studied intensively in the respiratory system. Surfactant protein A and surfactant protein D are proteins belonging to the family of collectins each playing a major role in the innate immune system.
Stefan Schob +7 more
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Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD
ERJ Open Research, 2022 Rationale Pulmonary surfactant is vital for lung homeostasis as it reduces surface tension to prevent alveolar collapse and provides essential immune-regulatory and antipathogenic functions.
Ventzislava A. Hristova +32 more
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Lung, 2020 SARS-CoV-2 (COVID-19) has infected more than 7 million people worldwide in the short time since it emerged in Wuhan, China in December 2019. The aim of this study was to investigate the relationship between serum interleukin 6 (IL-6) and surfactant ...
Buğra Kerget +6 more
semanticscholar +1 more source