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Cells, 2023 The transplantation of neural progenitors into a host brain represents a useful tool to evaluate the involvement of cell-autonomous processes and host local cues in the regulation of neuronal differentiation during the development of the mammalian brain.
Maria Llach Pou +6 more
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Frontiers in Cellular Neuroscience, 2023 Human induced pluripotent stem cells (hiPSCs) have been used extensively in vitro to model early events in neurodevelopment. Because of a number of shortcomings, previous work has established a potential to use these cells in vivo after transplantation ...
Célia Raïs +11 more
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Cell, 2004 The transmission of information across neuronal synapses is an energetically taxing business. Sheng and colleagues monitored the localization of mitochondria following different levels of synaptic activation and discovered that these organelles change their distribution in interesting ways, stalling near synapses when neurons are activated and ...
Schuman, E., Chan, D.
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Shiyan dongwu yu bijiao yixue, 2022 Objective To compare and explore the histopathological and ultrastructural characteristics of the olfactory bulb in 6- and 12-month-old APP/PS1 double-transgenic mice and their spatial learning and memory ability, as well as the effects of memantine ...
LIU Jiani +6 more
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Frontiers in Neuroscience, 2022 Bacterial infections are a common cause of morbidity and mortality in the elderly, and particularly in individuals with a neurodegenerative disease. Experimental models of neurodegeneration have shown that LPS-induced systemic inflammation increases ...
Joe K. Chouhan +3 more
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Cells, 2021 The extracellular matrix (ECM) plays a key role in synaptogenesis and the regulation of synaptic functions in the central nervous system. Recent studies revealed that in addition to dopaminergic and serotoninergic neuromodulatory systems, microglia also ...
Luisa Strackeljan +6 more
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The Journal of Neuroscience, 1996 The strength of many synapses is modified by various use and time-dependent processes, including facilitation and depression. A general description of synaptic transfer characteristics must account for the history-dependence of synaptic efficacy and should be able to predict the postsynaptic response to any temporal pattern of presynaptic activity.
K, Sen +3 more
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eLife, 2022 Connections from the basolateral amygdala (BLA) to medial prefrontal cortex (PFC) regulate memory and emotion and become disrupted in neuropsychiatric disorders.
Kasra Manoocheri, Adam G Carter
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Interaction and Subcellular Association of PRRT1/SynDIG4 With AMPA Receptors
Frontiers in Synaptic Neuroscience, 2021 AMPA receptors (AMPAR) are organized into supramolecular complexes in association with other membrane proteins that provide exquisite regulation of their biophysical properties and subcellular trafficking.
Emily Eischen Martin +3 more
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