Results 51 to 60 of about 471,836 (383)

The Immunological Synapse [PDF]

open access: yesCancer Immunology Research, 2003
AbstractThe molecular interactions underlying regulation of the immune response take place in a nanoscale gap between T cells and antigen-presenting cells, termed the immunological synapse. If these interactions are regulated appropriately, the host is defended against a wide range of pathogens and deranged host cells.
openaire   +6 more sources

Learning through ferroelectric domain dynamics in solid-state synapses

open access: yesNature Communications, 2017
In the brain, learning is achieved through the ability of synapses to reconfigure the strength by which they connect neurons (synaptic plasticity). In promising solid-state synapses called memristors, conductance can be finely tuned by voltage pulses and
S. Boyn   +15 more
semanticscholar   +1 more source

Les chaînes de traction des TGV

open access: yesComptes Rendus. Mécanique
This article describes the different components of the TGV drive trains, from the TGV SE (1st TGV) to the TGVM.
Goeres, David
doaj   +1 more source

Dark microglia: Why are they dark?

open access: yesCommunicative & Integrative Biology, 2016
Using transmission electron microscopy (TEM) we recently characterized a microglial phenotype that is induced by chronic stress, fractalkine receptor deficiency, aging, or Alzheimer disease pathology.
Kanchan Bisht   +3 more
doaj   +1 more source

Protein synthesis at synaptic sites on dendrites [PDF]

open access: yes, 2001
Studies over the past 20 years have revealed that gene expression in neurons is carried out by a distributed network of translational machinery. One component of this network is localized in dendrites, where polyribosomes and associated membranous ...
Schuman, Erin M., Steward, Oswald
core   +1 more source

Distinct subpopulations of ventral pallidal cholinergic projection neurons encode valence of olfactory stimuli

open access: yesCell Reports
Summary: To better understand the function of cholinergic projection neurons in the ventral pallidum (VP), we examined behavioral responses to appetitive (APP) and aversive (AV) odors that elicited approach or avoidance, respectively.
Ronald Kim   +4 more
doaj   +1 more source

Accumulation of Dense Core Vesicles in Hippocampal Synapses Following Chronic Inactivity. [PDF]

open access: yes, 2018
The morphology and function of neuronal synapses are regulated by neural activity, as manifested in activity-dependent synapse maturation and various forms of synaptic plasticity.
Bi, Guo-Qiang   +4 more
core   +2 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Cell-type specific innervation of cortical pyramidal cells at their apical dendrites

open access: yeseLife, 2020
We investigated the synaptic innervation of apical dendrites of cortical pyramidal cells in a region between layers (L) 1 and 2 using 3-D electron microscopy applied to four cortical regions in mouse.
Ali Karimi   +4 more
doaj   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas   +18 more
wiley   +1 more source

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