Results 51 to 60 of about 445,271 (401)
Annual Review of Immunology, 2001 The adaptive immune response is initiated by the interaction of T cell antigen receptors with major histocompatibility complex molecule-peptide complexes in the nanometer scale gap between a T cell and an antigen-presenting cell, referred to as an immunological synapse.
Bromley, S +9 more
openaire +4 more sources
A genetically encoded reporter of synaptic activity in vivo [PDF]
, 2009 To image synaptic activity within neural circuits, we tethered the genetically encoded calcium indicator (GECI) GCaMP2 to synaptic vesicles by fusion to synaptophysin. The resulting reporter, SyGCaMP2, detected the electrical activity of neurons with two
B Granseth +35 more
core +1 more source
Learning through ferroelectric domain dynamics in solid-state synapses
Nature Communications, 2017 In the brain, learning is achieved through the ability of synapses to reconfigure the strength by which they connect neurons (synaptic plasticity). In promising solid-state synapses called memristors, conductance can be finely tuned by voltage pulses and
S. Boyn +15 more
semanticscholar +1 more source
Diversity of neuronal activity is provided by hybrid synapses [PDF]
Nonlinear Dynamics ,2021, 2019 Many experiments have evidenced that electrical and chemical synapses -- hybrid synapses -- coexist in most organisms and brain structures. The role of electrical and chemical synapse connection in diversity of neural activity generation has been investigated separately in networks of varying complexities.
arxiv +1 more source
Spatial representation of temporal information through spike timing dependent plasticity [PDF]
, 2003 We suggest a mechanism based on spike time dependent plasticity (STDP) of synapses to store, retrieve and predict temporal sequences. The mechanism is demonstrated in a model system of simplified integrate-and-fire type neurons densely connected by STDP ...
A. Herz +45 more
core +3 more sources
Learning with Chemical versus Electrical Synapses -- Does it Make a Difference? [PDF]
arXiv, 2023 Bio-inspired neural networks have the potential to advance our understanding of neural computation and improve the state-of-the-art of AI systems. Bio-electrical synapses directly transmit neural signals, by enabling fast current flow between neurons.
arxiv
Is plasticity of synapses the mechanism of long-term memory storage?
npj Science of Learning, 2019 It has been 70 years since Donald Hebb published his formalized theory of synaptic adaptation during learning. Hebb’s seminal work foreshadowed some of the great neuroscientific discoveries of the following decades, including the discovery of long-term ...
W. Abraham, O. Jones, D. Glanzman
semanticscholar +1 more source
RNA, 2015 One reason we learn and remember is because synapses, the places where axons and dendrites meet, undergo experience-dependent changes whose long-lasting nature may underlie the formation and persistence of memory. Indeed, neurons use these morphological and biochemical alterations to distinguish experienced (i.e., stimulated) from naive (unstimulated ...
openaire +3 more sources
Identifiability of a Binomial Synapse [PDF]
Frontiers in Computational Neuroscience, 2020 Frontiers in Computational Neuroscience ...
Camille Gontier +2 more
openaire +5 more sources
A population of immature cerebellar parallel fibre synapses are insensitive to adenosine but are inhibited by hypoxia [PDF]
, 2011 The purine adenosine plays an important role in a number of physiological and pathological processes and is neuroprotective during hypoxia and ischemia.
Atterbury, Alison, Wall, Mark J.
core +1 more source