Results 81 to 90 of about 530,363 (319)
Aberrant location of inhibitory synaptic marker proteins in the hippocampus of dystrophin-deficient mice [PDF]
, 2014 Duchenne muscular dystrophy (DMD) is a neuromuscular disease that arises from mutations in the dystrophin-encoding gene. Apart from muscle pathology, cognitive impairment, primarily of developmental origin, is also a significant component of the disorder.
Zablocki, Krzysztof +11 more
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Characterization of auditory synaptic inputs to gerbil perirhinal cortex
Frontiers in Neural Circuits, 2015 The representation of acoustic cues involves regions downstream from the auditory cortex (ACx). One such area, the perirhinal cortex (PRh), processes sensory signals containing mnemonic information.
Vibhakar C Kotak +2 more
doaj +1 more source
Mathematica Slovaca, 2010 Abstract A synaptic algebra is both a special Jordan algebra and a spectral order-unit normed space satisfying certain natural conditions suggested by the partially ordered Jordan algebra of bounded Hermitian operators on a Hilbert space. The adjective “synaptic”, borrowed from biology, is meant to suggest that such an algebra coherently
openaire +2 more sources
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Feedforward inhibition and synaptic scaling - two sides of the same coin?
, 2012 Feedforward inhibition and synaptic scaling are important adaptive processes that control the total input a neuron can receive from its afferents. While often studied in isolation, the two have been reported to co-occur in various brain regions.
Cristina Savin +11 more
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Communications Biology, 2023 Curiosity, or novelty seeking, is a fundamental mechanism motivating animals to explore and exploit environments to improve survival, and is also positively associated with cognitive, intrapersonal and interpersonal well-being in humans.
Qiang Shan +4 more
doaj +1 more source
Advances in Physiology Education, 2014 PHYSIOLOGY has long been recognized as a subject that is difficult for students to master. Medical students, in particular, often fail to appreciate the relevance of learning and understanding normal body functions for their clinical studies (11). Over the past two decades, there has been increasing recognition in the physiology education literature of
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Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
, 2011 Here we consider the possibility that a fundamental function of sensory cortex is the generation of an internal simulation of sensory environment in real-time.
Saeed Tavazoie (7618) +3 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source