Results 1 to 10 of about 571,868 (347)
Synaptic plasticity as Bayesian inference [PDF]
Published in Nature Neuroscience: https://www.nature.com/articles/s41593-021-00809 ...
Laurence Aitchison+8 more
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LRP4 is required for the olfactory association task in the piriform cortex
Background Low-density lipoprotein receptor-related protein 4 (LRP4) plays a critical role in the central nervous system (CNS), including hippocampal synaptic plasticity, maintenance of excitatory synaptic transmission, fear regulation, as well as long ...
Min Yan+12 more
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Metabotropic Regulation of Synaptic Plasticity [PDF]
descripción no proporcionada por ...
Fernández de Sevilla García, David+3 more
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Microglia regulate synaptic development and plasticity
Synapses are fundamental structures of neural circuits that transmit information between neurons. Thus, the process of neural circuit formation via proper synaptic connections shapes the basis of brain functions and animal behavior. Synapses continuously
Megumi Andoh, R. Koyama
semanticscholar +1 more source
Impaired synaptic incorporation of AMPA receptors in a mouse model of fragile X syndrome
Fragile X syndrome (FXS) is the most common monogenetic cause of inherited intellectual disability and autism in humans. One of the well-characterized molecular phenotypes of Fmr1 KO mice, a model of FXS, is increased translation of synaptic proteins ...
Magdalena Chojnacka+7 more
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Subcellular RNA-seq for the Analysis of the Dendritic and Somatic Transcriptomes of Single Neurons
In neurons, local translation in dendritic and axonal compartments allows for the fast and on-demand modification of the local proteome. As the last few years have witnessed dramatic advancements in our appreciation of the brain’s neuronal diversity, it ...
Julio Perez, Erin Schuman
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Burst-dependent synaptic plasticity can coordinate learning in hierarchical circuits
Synaptic plasticity is believed to be a key physiological mechanism for learning. It is well established that it depends on pre- and postsynaptic activity.
A. Payeur+4 more
semanticscholar +1 more source
Metformin, a first-line drug for type 2 diabetes mellitus (T2DM), has been found to reduce depressive symptoms in patients with comorbid depression and other diseases.
Jiang Chen+6 more
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Optogenetics and synaptic plasticity [PDF]
The intricate and complex interaction between different populations of neurons in the brain has imposed limits on our ability to gain detailed understanding of synaptic transmission and its integration when employing classical electrophysiological approaches. Indeed, electrical field stimulation delivered via traditional microelectrodes does not permit
John F. MacDonald+3 more
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Neuromodulation of the feedforward dentate gyrus-CA3 microcircuit
The feedforward dentate gyrus-CA3 microcircuit in the hippocampus is thought to activate ensembles of CA3 pyramidal cells and interneurons to encode and retrieve episodic memories.
Luke Yuri Prince+3 more
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