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Learning with Delayed Synaptic Plasticity [PDF]
Proceedings of the Genetic and Evolutionary Computation Conference, 2019 The plasticity property of biological neural networks allows them to perform learning and optimize their behavior by changing their configuration. Inspired by biology, plasticity can be modeled in artificial neural networks by using Hebbian learning ...
Fletcher, George +4 more
core +7 more sources
Network self-organization explains the statistics and dynamics of synaptic connection strengths in cortex [PDF]
, 2013 The information processing abilities of neural circuits arise from their synaptic connection patterns. Understanding the laws governing these connectivity patterns is essential for understanding brain function.
Dimitrakakis, Christos +2 more
core +17 more sources
iScience, 2021 Summary: It is well established that long-term depression (LTD) can be initiated by either NMDA or mGluR activation. Here we report that sustained activation of GluK2 subunit-containing kainate receptors (KARs) leads to α-amino-3-hydroxy-5-methyl-4 ...
Jithin D. Nair +8 more
doaj +1 more source
Microglia regulation of synaptic plasticity and learning and memory
Neural Regeneration Research, 2021 Microglia are the resident macrophages of the central nervous system. Microglia possess varied morphologies and functions. Under normal physiological conditions, microglia mainly exist in a resting state and constantly monitor their microenvironment and ...
J. Cornell +3 more
semanticscholar +1 more source
GluK2 Q/R editing regulates kainate receptor signaling and long-term potentiation of AMPA receptors
iScience, 2023 Summary: Q/R editing of the kainate receptor (KAR) subunit GluK2 radically alters recombinant KAR properties, but the effects on endogenous KARs in vivo remain largely unexplored.
Jithin D. Nair +6 more
doaj +1 more source
Synaptic plasticity and mental health: methods, challenges and opportunities
Neuropsychopharmacology, 2022 Activity-dependent synaptic plasticity is a ubiquitous property of the nervous system that allows neurons to communicate and change their connections as a function of past experiences.
L. Appelbaum +3 more
semanticscholar +1 more source
Communications Biology, 2023 Curiosity, or novelty seeking, is a fundamental mechanism motivating animals to explore and exploit environments to improve survival, and is also positively associated with cognitive, intrapersonal and interpersonal well-being in humans.
Qiang Shan +4 more
doaj +1 more source
Imaging synaptic plasticity [PDF]
Molecular Brain, 2011 Over the past decade, the use and development of optical imaging techniques has advanced our understanding of synaptic plasticity by offering the spatial and temporal resolution necessary to examine long-term changes at individual synapses. Here, we review the use of these techniques in recent studies of synaptic plasticity and, in particular, long ...
Padamsey, Z, Emptage, N
openaire +5 more sources
Journal of Medical Case Reports, 2022 Background The globus pallidus internus is the main target for the treatment of dystonia by deep brain stimulation. Unfortunately, for some genetic etiologies, the therapeutic outcome of dystonia is less predictable.
Andrea Giorni +5 more
doaj +1 more source
Simultaneous emulation of synaptic and intrinsic plasticity using a memristive synapse
Nature Communications, 2022 Neuromorphic computing targets the hardware embodiment of neural network, and device implementation of individual neuron and synapse has attracted considerable attention.
S. Sung +4 more
semanticscholar +1 more source