Results 11 to 20 of about 703,287 (417)
A Mathematical Model of Tripartite Synapse: Astrocyte Induced Synaptic Plasticity [PDF]
, 2011 In this paper we present a biologically detailed mathematical model of tripartite synapses, where astrocytes modulate short-term synaptic plasticity. The model consists of a pre-synaptic bouton, a post-synaptic dendritic spine-head, a synaptic cleft and a peri-synaptic astrocyte controlling Ca2+ dynamics inside the synaptic bouton.
Majumdar, Kaushik, Tewari, Shivendra
arxiv +3 more sources
Effects of Synaptic and Myelin Plasticity on Learning in a Network of Kuramoto Phase Oscillators [PDF]
, 2019 Models of learning typically focus on synaptic plasticity. However, learning is the result of both synaptic and myelin plasticity. Specifically, synaptic changes often co-occur and interact with myelin changes, leading to complex dynamic interactions between these processes.
D. Dibenedetto +10 more
arxiv +5 more sources
Astrocytes: orchestrating synaptic plasticity? [PDF]
Neuroscience, 2015 Synaptic plasticity is the capacity of a preexisting connection between two neurons to change in strength as a function of neural activity. Because synaptic plasticity is the major candidate mechanism for learning and memory, the elucidation of its constituting mechanisms is of crucial importance in many aspects of normal and pathological brain ...
M. De Pittà +3 more
arxiv +10 more sources
Learning with Delayed Synaptic Plasticity [PDF]
Proceedings of the Genetic and Evolutionary Computation Conference, 2019 The plasticity property of biological neural networks allows them to perform learning and optimize their behavior by changing their configuration. Inspired by biology, plasticity can be modeled in artificial neural networks by using Hebbian learning ...
Fletcher, George +4 more
core +7 more sources
Synaptic nanomodules underlie the organization and plasticity of spine synapses. [PDF]
Nature Neuroscience, 2018 Experience results in long-lasting changes in dendritic spine size, yet how the molecular architecture of the synapse responds to plasticity remains poorly understood. Here a combined approach of multicolor stimulated emission depletion microscopy (STED)
Dalva, Matthew B. +4 more
core +3 more sources
Network self-organization explains the statistics and dynamics of synaptic connection strengths in cortex [PDF]
, 2013 The information processing abilities of neural circuits arise from their synaptic connection patterns. Understanding the laws governing these connectivity patterns is essential for understanding brain function.
Dimitrakakis, Christos +2 more
core +20 more sources
Microglia regulation of synaptic plasticity and learning and memory
Neural Regeneration Research, 2021 Microglia are the resident macrophages of the central nervous system. Microglia possess varied morphologies and functions. Under normal physiological conditions, microglia mainly exist in a resting state and constantly monitor their microenvironment and ...
J. Cornell +3 more
semanticscholar +1 more source
Synaptic plasticity and mental health: methods, challenges and opportunities
Neuropsychopharmacology, 2022 Activity-dependent synaptic plasticity is a ubiquitous property of the nervous system that allows neurons to communicate and change their connections as a function of past experiences.
L. Appelbaum +3 more
semanticscholar +1 more source
Communications Biology, 2023 Curiosity, or novelty seeking, is a fundamental mechanism motivating animals to explore and exploit environments to improve survival, and is also positively associated with cognitive, intrapersonal and interpersonal well-being in humans.
Qiang Shan +4 more
doaj +1 more source
Imaging synaptic plasticity [PDF]
Molecular Brain, 2011 Over the past decade, the use and development of optical imaging techniques has advanced our understanding of synaptic plasticity by offering the spatial and temporal resolution necessary to examine long-term changes at individual synapses. Here, we review the use of these techniques in recent studies of synaptic plasticity and, in particular, long ...
Padamsey, Z, Emptage, N
openaire +5 more sources