Results 11 to 20 of about 566,073 (388)
Astrocytes: orchestrating synaptic plasticity? [PDF]
Neuroscience, 2015 Synaptic plasticity is the capacity of a preexisting connection between two neurons to change in strength as a function of neural activity. Because synaptic plasticity is the major candidate mechanism for learning and memory, the elucidation of its constituting mechanisms is of crucial importance in many aspects of normal and pathological brain ...
M. De Pittà +3 more
arxiv +10 more sources
Microglia regulation of synaptic plasticity and learning and memory
Neural Regeneration Research, 2021 Microglia are the resident macrophages of the central nervous system. Microglia possess varied morphologies and functions. Under normal physiological conditions, microglia mainly exist in a resting state and constantly monitor their microenvironment and ...
J. Cornell +3 more
semanticscholar +1 more source
Synaptic plasticity and mental health: methods, challenges and opportunities
Neuropsychopharmacology, 2022 Activity-dependent synaptic plasticity is a ubiquitous property of the nervous system that allows neurons to communicate and change their connections as a function of past experiences.
L. Appelbaum +3 more
semanticscholar +1 more source
Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022 Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh +5 more
wiley +1 more source
Communications Biology, 2023 Curiosity, or novelty seeking, is a fundamental mechanism motivating animals to explore and exploit environments to improve survival, and is also positively associated with cognitive, intrapersonal and interpersonal well-being in humans.
Qiang Shan +4 more
doaj +1 more source
Imaging synaptic plasticity [PDF]
Molecular Brain, 2011 Over the past decade, the use and development of optical imaging techniques has advanced our understanding of synaptic plasticity by offering the spatial and temporal resolution necessary to examine long-term changes at individual synapses. Here, we review the use of these techniques in recent studies of synaptic plasticity and, in particular, long ...
Padamsey, Z, Emptage, N
openaire +5 more sources
Journal of Medical Case Reports, 2022 Background The globus pallidus internus is the main target for the treatment of dystonia by deep brain stimulation. Unfortunately, for some genetic etiologies, the therapeutic outcome of dystonia is less predictable.
Andrea Giorni +5 more
doaj +1 more source
Caspases in synaptic plasticity [PDF]
Molecular Brain, 2012 Caspases are a family of cysteine proteases that play key roles in programmed cell death (apoptosis). Mounting evidence in recent years shows that caspases also have important non-apoptotic functions in multiple cellular processes, such as synaptic plasticity, dendritic development, learning and memory. In this article, we review the studies on the non-
Morgan Sheng, Zheng Li
openaire +4 more sources
Simultaneous emulation of synaptic and intrinsic plasticity using a memristive synapse
Nature Communications, 2022 Neuromorphic computing targets the hardware embodiment of neural network, and device implementation of individual neuron and synapse has attracted considerable attention.
S. Sung +4 more
semanticscholar +1 more source
Synaptic plasticity as Bayesian inference [PDF]
Nature Neuroscience, 2021 Published in Nature Neuroscience: https://www.nature.com/articles/s41593-021-00809 ...
Laurence Aitchison +8 more
openaire +6 more sources