Results 61 to 70 of about 565,974 (289)
Cell Reports, 2016 Place cell firing patterns reactivated during hippocampal sharp-wave ripples (SWRs) in rest or sleep are thought to induce synaptic plasticity and thereby promote the consolidation of recently encoded information.
Josef H.L.P. Sadowski +2 more
doaj +1 more source
BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity
Cellular and molecular neurobiology, 2017 Brain-derived neurotrophic factor (BDNF) is one of the most widely distributed and extensively studied neurotrophins in the mammalian brain. Among its prominent functions, one can mention control of neuronal and glial development, neuroprotection, and ...
P. Kowiański +5 more
semanticscholar +1 more source
Nature Communications, 2021 In this study, acetylcholine release is shown to reorganise hippocampal CA1 inhibitory networks resulting in prioritisation of entorhinal input over CA3 input. This is achieved by activation of a combination of M3 and M4 muscarinic receptors.
Jon Palacios-Filardo +7 more
doaj +1 more source
Fluctuation-driven plasticity allows for flexible rewiring of neuronal assemblies [PDF]
arXiv, 2022 Synaptic connections in neuronal circuits are modulated by pre- and post-synaptic spiking activity. Heuristic models of this process of synaptic plasticity can provide excellent fits to results from in-vitro experiments in which pre- and post-synaptic spiking is varied in a controlled fashion.
arxiv
Synaptic Plasticity Dynamics for Deep Continuous Local Learning (DECOLLE)
Frontiers in Neuroscience, 2018 A growing body of work underlines striking similarities between biological neural networks and recurrent, binary neural networks. A relatively smaller body of work, however, addresses the similarities between learning dynamics employed in deep artificial
Jacques Kaiser, H. Mostafa, E. Neftci
semanticscholar +1 more source
Modulation of synaptic plasticity by glutamatergic gliotransmission: A modeling study [PDF]
Neural Plasticity, volume 2016 (2016), Article ID 7607924, 2016 Glutamatergic gliotransmission, that is the release of glutamate from perisynaptic astrocyte processes in an activity-dependent manner, has emerged as a potentially crucial signaling pathway for regulation of synaptic plasticity, yet its modes of expression and function in vivo remain unclear.
arxiv +1 more source
Behavioral time scale synaptic plasticity underlies CA1 place fields
Science, 2017 A different form of synaptic plasticity How do synaptic or other neuronal changes support learning? This subject has been dominated by Hebb's postulate of synaptic change.
Katie C. Bittner +4 more
semanticscholar +1 more source
Calcineurin, Synaptic Plasticity, and Memory [PDF]
The Scientific World JOURNAL, 2001 A long-held hypothesis in neuroscience holds that learning and memory mechanisms involve lasting changes in synaptic weights. Multiple mechanisms for producing such changes exist, of which NMDA-receptor–dependent long-term potentiation (LTP) is the most widely studied.
Carl Weitlauf, Danny G. Winder
openaire +3 more sources
Estimating the synaptic current in a multi-conductance AMPA receptor model [PDF]
, 2010 A pre-synaptic neuron releases diffusing neurotransmitters such as glutamate that activate post-synaptic receptors. The amplitude of the post-synaptic current, mostly mediated by glutamatergic (AMPARs) receptors, is a fundamental signal that may generate an action potential.
arxiv +1 more source
Metabolic constraints on synaptic learning and memory [PDF]
Journal of Neurophysiology 122: 1473-1490 (2019), 2019 Dendritic spines, the carriers of long-term memory, occupy a small fraction of cortical space, and yet they are the major consumers of brain metabolic energy. What fraction of this energy goes for synaptic plasticity, correlated with learning and memory?
arxiv +1 more source