Results 61 to 70 of about 724,295 (381)
Glial Cells and Synaptic Plasticity [PDF]
Neural Plasticity, 2016 Neuroglia are composed of highly heterogeneous cellular populations of neural (astrocytes, oligodendrocytes, and NG2 glial cells) and nonneural (microglia) origin that are essential for maintaining efficient neurotransmission, homeostatic cascades, supply of energy metabolites, turnover of neurotransmitters, and establishment of the blood-brain barrier
Fushun Wang +4 more
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Endoplasmic reticulum visits highly active spines and prevents runaway potentiation of synapses
Nature Communications, 2020 In hippocampal pyramidal cells, a subset of dendritic spines contain endoplasmic reticulum (ER). Here, the authors show that ER enters dendritic spines in a non-random manner, during high synaptic activity with the function of limiting synaptic strength.
Alberto Perez-Alvarez +5 more
doaj +1 more source
Alterations in brain connectivity due to plasticity and synaptic delay
, 2017 Brain plasticity refers to brain's ability to change neuronal connections, as a result of environmental stimuli, new experiences, or damage. In this work, we study the effects of the synaptic delay on both the coupling strengths and synchronisation in a ...
Batista, A. M. +8 more
core +1 more source
SUMOylation of FOXP1 regulates transcriptional repression via CtBP1 to drive dendritic morphogenesis
Scientific Reports, 2017 Forkhead Box P (FOXP) transcriptional repressors play a major role in brain development and their dysfunction leads to human cognitive disorders. However, little is known about how the activity of these proteins is regulated.
Daniel L. Rocca +2 more
doaj +1 more source
Cell Reports, 2017 Summary: Ionotropic glutamate receptor (iGluR) trafficking and function underpin excitatory synaptic transmission and plasticity and shape neuronal networks.
Ashley J. Evans +4 more
doaj +1 more source
A Mathematical Model of Tripartite Synapse: Astrocyte Induced Synaptic Plasticity
, 2012 In this paper we present a biologically detailed mathematical model of tripartite synapses, where astrocytes modulate short-term synaptic plasticity. The model consists of a pre-synaptic bouton, a post-synaptic dendritic spine-head, a synaptic cleft and ...
Majumdar, Kaushik, Tewari, Shivendra
core +1 more source
Sleep and protein synthesis-dependent synaptic plasticity: impacts of sleep loss and stress [PDF]
, 2014 Sleep has been ascribed a critical role in cognitive functioning. Several lines of evidence implicate sleep in the consolidation of synaptic plasticity and long-term memory.
Bramham, Clive R. +2 more
core +1 more source
Nature Neuroscience, 2019 Microglia are the brain’s resident innate immune cells and also have a role in synaptic plasticity. Microglial processes continuously survey the brain parenchyma, interact with synaptic elements and maintain tissue homeostasis.
Rianne D. Stowell +10 more
semanticscholar +1 more source
Learning to Discriminate Through Long-Term Changes of Dynamical Synaptic Transmission [PDF]
, 2008 Short-term synaptic plasticity is modulated by long-term synaptic changes. There is, however, no general agreement on the computational role of this interaction.
Gundlfinger, Anja +4 more
core +2 more sources
Synaptic Plasticity and the Warburg Effect [PDF]
Cell Metabolism, 2014 Functional brain imaging studies show that in certain brain regions glucose utilization exceeds oxygen consumption, indicating the predominance of aerobic glycolysis. In this issue, Goyal et al. (2014) report that this metabolic profile is associated with an enrichment in the expression of genes involved in synaptic plasticity and remodeling processes.
Pierre J. Magistretti +2 more
openaire +4 more sources