Results 91 to 100 of about 2,697,657 (391)

Minireview: pH and synaptic transmission [PDF]

FEBS Letters, 2013
As a general rule a rise in pH increases neuronal activity, whereas it is dampened by a fall of pH. Neuronal activity per se also challenges pH homeostasis by the increase of metabolic acid equivalents. Moreover, the negative membrane potential of neurons promotes the intracellular accumulation of protons.
Anne Sinning, Anne Sinning, Christian A. Hübner   +2 more
openaire   +3 more sources

Biomimetic Design of Biocompatible Neural Probes for Deep Brain Signal Monitoring and Stimulation: Super Static Interface for Immune Response‐Enhanced Contact

Advanced Functional Materials, EarlyView.
Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Seon Yeong Chae, Min Jae Kim, Ki Jun Yu, Hwa Kyoung Shin, Suck Won Hong   +7 more
wiley   +1 more source

Caveolin-1 deficiency impairs synaptic transmission in hippocampal neurons

Molecular Brain, 2021
In addition to providing structural support, caveolin-1 (Cav1), a component of lipid rafts, including caveolae, in the plasma membrane, is involved in various cellular mechanisms, including signal transduction. Although pre-synaptic membrane dynamics and
Soulmee Koh, Wongyoung Lee, Sang Myun Park, Sung Hyun Kim   +3 more
doaj   +1 more source

Equivalence between synaptic current dynamics and heterogeneous propagation delays in spiking neuron networks [PDF]

, 2017
Message passing between components of a distributed physical system is non-instantaneous and contributes to determine the time scales of the emerging collective dynamics like an effective inertia. In biological neuron networks this inertia is due in part to local synaptic filtering of exchanged spikes, and in part to the distribution of the axonal ...
arxiv   +1 more source

Ultra‐Fast Non‐Volatile Resistive Switching Devices with Over 512 Distinct and Stable Levels for Memory and Neuromorphic Computing

Advanced Functional Materials, EarlyView.
A materials and device design concept that comprises a self‐assembled ultra‐thin epitaxial ion‐transporting layer, an amorphous oxide overcoat oxygen‐blocking layer, and a partial filament formed during an electroforming step is proposed for low‐current multilevel resistive switching devices.
Ming Xiao, Markus Hellenbrand, Nives Strkalj, Babak Bakhit, Zhuotong Sun, Nikolaos Barmpatsalos, Dovydas Joksas, Hongyi Dou, Zedong Hu, Ping Lu, Samip Karki, Sundar Kunwar, Jonathan D. Major, Aiping Chen, Haiyan Wang, Quanxi Jia, Adnan Mehonic, Judith L. MacManus‐Driscoll   +17 more
wiley   +1 more source

Slow synaptic transmission in frog sympathetic ganglia [PDF]

, 1986
Bullfrog ganglia contain two classes of neurone, B and C cells, which receive different inputs and exhibit different slow synaptic potentials. B cells, to which most effort has been directed, possess slow and late slow EPSPs.
Adams, P. R., Brown, D. A., Jones, S. W., Koch, Christof, Lancaster, B., Pennefeather, P.   +5 more
core   +2 more sources

Facilitatory actions of guanidine on synaptic transmission in mammalian brain slices [PDF]

, 1979
Guanidine administration may be beneficial in the treatment of amyotrophic lateral sclerosis and related diseases; however, the actions of guanidine on the mammalian central nervous system have not been investigated.
Galvan, Martin, Grafe, Peter, Ten Bruggencate, Gerrit   +2 more
core   +1 more source

Transient Current Responses of Organic Electrochemical Transistors: Evaluating Ion Diffusion, Chemical Capacitance, and Series Elements

Advanced Functional Materials, EarlyView.
This work establishes a general theory of the current transient of ionic‐electronic transistors under a step of gate voltage. The dominant effect is a transient charging of the channel by diffusion of ions. The additional influence of electrolyte capacitance and resistance splits the fundamental time constant of diffusion into two different components.
Juan Bisquert, Nir Tessler
wiley   +1 more source

Genetic background determines synaptic phenotypes in Arid1b-mutant mice

Frontiers in Psychiatry
ARID1B, a chromatin remodeler, is strongly implicated in autism spectrum disorders (ASD). Two previous studies on Arid1b-mutant mice with the same exon 5 deletion in different genetic backgrounds revealed distinct synaptic phenotypes underlying the ...
Hyosang Kim, Eunjoon Kim, Eunjoon Kim
doaj   +1 more source

Acid-Sensing Ion Channels Activated by Evoked Released Protons Modulate Synaptic Transmission at the Mouse Calyx of Held Synapse [PDF]

, 2017
Acid-sensing ion channels (ASICs) regulate synaptic activities and play important roles in neurodegenerative diseases. We found that these channels can be activated in neurons of the medial nucleus of the trapezoid body (MNTB) of the auditory system in ...
Di Guilmi, Mariano Nicolás, González Inchauspe, Carlota María Fabiola, Uchitel, Osvaldo Daniel, Urbano Suarez, Francisco Jose   +3 more
core   +1 more source