Results 11 to 20 of about 2,697,657 (391)
Modulation of synaptic transmission through O-GlcNAcylation [PDF]
Molecular BrainO-GlcNAcylation is a posttranslational modification where N-acetylglucosamine (O-GlcNAc) is attached and detached from a serine/threonine position by two enzymes: O-GlcNAc transferase and O-GlcNAcase.
Seunghyo Han +5 more
doaj +2 more sources
Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair. [PDF]
Nature Neuroscience, 2015 Contrary to the long-held belief that DNA methylation of terminally differentiated cells is permanent and essentially immutable, post-mitotic neurons exhibit extensive DNA demethylation.
Coppola, Giovanni +10 more
core +2 more sources
Synaptic Cleft Segmentation in Non-Isotropic Volume Electron Microscopy of the Complete Drosophila Brain [PDF]
arXiv, 2018 Neural circuit reconstruction at single synapse resolution is increasingly recognized as crucially important to decipher the function of biological nervous systems. Volume electron microscopy in serial transmission or scanning mode has been demonstrated to provide the necessary resolution to segment or trace all neurites and to annotate all synaptic ...
A Jenett +20 more
arxiv +3 more sources
Synaptic adhesion molecules and excitatory synaptic transmission
Current Opinion in Neurobiology, 2017 Synaptic adhesion molecules have been extensively studied for their contribution to the regulation of synapse development through trans-synaptic adhesions. However, accumulating evidence increasingly indicates that synaptic adhesion molecules are also involved in the regulation of excitatory synaptic transmission and plasticity, often through direct or
Eunjoon Kim, Hyejin Lee, Seil Jang
openaire +4 more sources
ERRα regulates synaptic transmission through reactive oxygen species in hippocampal neurons [PDF]
HeliyonReactive oxygen species (ROS) play multiple roles in synaptic transmission, and estrogen-related receptor α (ERRα) is involved in regulating ROS production.
De-Mei Xu +4 more
doaj +2 more sources
Molecular Psychiatry, 2021 The prefrontal cortex (PFC) serves as the chief executive officer of the brain, controlling the highest level cognitive and emotional processes. Its local circuits among glutamatergic principal neurons and GABAergic interneurons, as well as its long ...
Zhen Yan, Benjamin Rein
semanticscholar +1 more source
Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022 Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh +5 more
wiley +1 more source
Journal of Experimental & Clinical Cancer Research, 2021 This article has been retracted.
Jie Yuan +7 more
doaj +1 more source