Results 11 to 20 of about 2,712,162 (368)
A theory of synaptic transmission [PDF]
eLife, 2021 Rapid and precise neuronal communication is enabled through a highly synchronous release of signaling molecules neurotransmitters within just milliseconds of the action potential.
Bin Wang, Olga K Dudko
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Harvard Data Science Review, 2018 In this chapter, we will first discuss chemical synapses, which use chemical signaling to convey information between the pre- and postsynaptic neurons, and then we will look at electrical synapses, which are a more basic but important second type of synapse that relies on direct electrical signaling.
Flavio Fröhlich
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Turbocharging synaptic transmission
FEBS Letters, 2023 Evidence from biochemistry, genetics, and electron microscopy strongly supports the idea that a ring of Synaptotagmin is central to the clamping and release of synaptic vesicles (SVs) for synchronous neurotransmission. Recent direct measurements in cell‐free systems suggest there are 12 SNAREpins in each ready‐release vesicle, consisting of six ...
James E. Rothman +3 more
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Bio-Protocol, 2023 Synapses provide the main route of signal transduction within neuronal networks. Many factors regulate critical synaptic functions. These include presynaptic calcium channels, triggering neurotransmitter release, and postsynaptic ionotropic receptors ...
Ruslan Stanika, Gerald Obermair
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Nature Communications, 2020 Autism spectrum disorder (ASD) is thought to result from deviation from normal development of neural circuits and synaptic function. Many genes with mutation in ASD patients have been identified.
H. Sacai +8 more
semanticscholar +1 more source
Amyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2. [PDF]
, 2012 BACKGROUND: It is becoming increasingly evident that deficits in the cortex and hippocampus at early stages of dementia in Alzheimer's disease (AD) are associated with synaptic damage caused by oligomers of the toxic amyloid-β peptide (Aβ42).
Alifragis, P +5 more
core +7 more sources
Frontiers in Synaptic Neuroscience, 2020 Synaptic transmission between neurons is the basic mechanism for information processing in cortical microcircuits. To date, paired recording from synaptically coupled neurons is the most widely used method which allows a detailed functional ...
Guanxiao Qi +5 more
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Frontiers in Systems Neuroscience, 2021 Sensory information is transferred to the cerebellar cortex via the mossy fiber–granule cell (MF–GC) pathway, which participates in motor coordination and motor learning.
Bing-Xue Li +13 more
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