Results 81 to 90 of about 169,161 (276)

A legend of the SNARE complex and synaptotagmin—the insight into synaptic transmission [PDF]

, 2013
Jianyuan Sun
openalex   +1 more source

Biomaterials‐Based Hydrogel with Superior Bio‐Mimetic Ionic Conductivity and Tissue‐Matching Softness for Bioelectronics

Advanced Functional Materials, EarlyView.
By mimicking the ion‐accelerating effect of ion channel receptors in neuron membranes, a biomaterials‐based ionic hydrogel (BIH) is developed, which offers a high ionic conductivity of 7.04 S m−1, outperforming conventional chitosan, cellulose, agarose, starch, and gelatin based ionic hydrogels.
Baojin Chen, Renjie Yu, Jiaqi Wang, Yunxiang Feng, Yujie Zhang, Yanchao Mao, Chongxin Shan, Xudong Wang   +7 more
wiley   +1 more source

mGluR5-mediated astrocytes hyperactivity in the anterior cingulate cortex contributes to neuropathic pain in male mice

Communications Biology
Astrocytes regulate synaptic transmission in healthy and pathological conditions, but their involvement in modulating synaptic transmission in chronic pain is unknown.
Weida Shen, Fujian Chen, Yejiao Tang, Yulu Zhao, Linjing Zhu, Liyang Xiang, Li Ning, Wen Zhou, Yiran Chen, Liangxue Wang, Jing Li, Hui Huang, Ling-Hui Zeng   +12 more
doaj   +1 more source

Past and Future of Analog-Digital Modulation of Synaptic Transmission

Frontiers in Cellular Neuroscience, 2019
Action potentials (APs) are generally produced in response to complex summation of excitatory and inhibitory synaptic inputs. While it is usually considered as a digital event, both the amplitude and width of the AP are significantly impacted by the ...
Mickael Zbili, Mickael Zbili, Dominique Debanne   +2 more
doaj   +1 more source

Controlling Intestinal Organoid Polarity using Synthetic Dynamic Hydrogels Decorated with Laminin‐Derived IKVAV Peptides

Advanced Healthcare Materials, EarlyView.
Design rules are presented to control intestinal organoid polarity in fully synthetic hydrogels. The laminin‐derived IKVAV sequence is crucial to obtain correct intestinal organoid polarity. Increasing hydrogel dynamics further supports the growth of correctly polarized intestinal organoids, while a bulk level of stiffness (G’ ≈ 0.7 kPa) is crucial to ...
Laura Rijns, Joost A. P. M. Wijnakker, Victor A. Veenbrink, Riccardo Bellan, Fenna W. B. Craenmehr, Simone I. S. Hendrikse, Johnick F. van Sprang, Wim de Lau, E. W. Meijer, Hans Clevers, Patricia Y. W. Dankers   +10 more
wiley   +1 more source

Presynaptic depression of synaptic transmission mediated by activation of metabotropic glutamate receptors in rat neocortex [PDF]

, 1994
JP Burke, JJ Hablitz
openalex   +1 more source

Modular Platform for Rapidly Investigating Long‐Distance Propagation of Human Neural Network Activity

Advanced Healthcare Materials, EarlyView.
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel, Sailee Sham Lavekar, Ronak Jaisalmeria, Suki Oji, Jazmine Jayasi, Caroline Cvetkovic, Robert Krencik   +6 more
wiley   +1 more source

Loss of Predominant Shank3 Isoforms Results in Hippocampus-Dependent Impairments in Behavior and Synaptic Transmission [PDF]

, 2013
Mehreen Kouser, Haley E. Speed, Colleen M. Dewey, Jeremy M. Reimers, Allie J. Widman, Natasha Gupta, Shunan Liu, Thomas C. Jaramillo, Muhammad Bangash, Bo Xiao, Paul Worley, Craig M. Powell   +11 more
openalex   +1 more source

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

Fluoxetine (Prozac) and Serotonin Act on Excitatory Synaptic Transmission to Suppress Single Layer 2/3 Pyramidal Neuron-Triggered Cell Assemblies in the Human Prefrontal Cortex [PDF]

, 2012
Gergely Komlósi, Gábor Molnár, Márton Rózsa, Szabolcs Oláh, Pál Barzó, Gábor Tamás   +5 more
openalex   +1 more source