Results 291 to 300 of about 107,361 (347)

RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors. [PDF]

J Cell Biol
Dou D, Aiken J, Holzbaur ELF.
europepmc   +1 more source

Psilocybin as a novel treatment for chronic pain

British Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey, Reena Lasrado, Maria Maiarú, Gary J. Stephens   +3 more
wiley   +1 more source

Synaptic Vesicle Cycling Disorders: Cross-Sectional Phenotyping Study of a Gene Functional Network

Eck J, Smith T, Kolesnik A, Al-jawahiri R, Baker K.   +4 more
europepmc   +1 more source

Biallelic variants in the synaptic vesicle glycoprotein 2 A are associated with epileptic encephalopathy. [PDF]

Eur J Hum Genet
Al-Maawali A, Al-Murshedi F, Al-Futaisi A, Mansy A, Al-Habsi A, Girisha KM.   +5 more
europepmc   +1 more source

Contributions of synaptic energetic dysfunction by microtubule dynamics and microtubule‐based mitochondrial transport disorder to morphine tolerance

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Morphine is among the most powerful analgesic, but its long‐term use can cause tolerance. Synaptic ATP supply is critical for maintaining synaptic transmission. Microtubule‐based mitochondrial transport ensures synaptic energy supply.
Zheng Li, Jie Liu, Jie Ju, Xiaoling Peng, Wei Zhao, Jihao Ren, Xiaoqian Jia, Jihong Wang, Ye Tu, Feng Gao   +9 more
wiley   +1 more source

Reduced levels of synaptic vesicle protein 2A in the extracellular vesicles and brain of Alzheimer’s disease- associations with Aβ, tau and synaptophysin

Nussbaumer J, Barve A, Zufferey V, Espourteille J, Kirabali T, Konietzko U, Razansky D, Rominger A, Nordberg A, Buée L, Colin M, Nitsch RM, Hock C, Richetin K, Ni R.   +14 more
europepmc   +1 more source

Exposure to an enriched environment modulates the synaptic vesicle cycle in a mouse spinal cord injury model. [PDF]

Sci Rep
Yoo J, Shin JC, Lim KB, Kim SH, Kim HS, Kim SH, Baek D, Jo S, Kim J, Baek A, Cho SR.   +10 more
europepmc   +1 more source

Experimental Parkinsonism induced by tetanus toxin injected into basal ganglia

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Local inhibitory circuits and long‐range inhibitory projections within the interconnected basal ganglia nuclei are critical for control of voluntary movement and pathophysiology of different extrapyramidal movement disorders.
Patrik Meglić, Petra Šoštarić, Davor Virag, Ana Knezović, Nikola Habek, Ornella Rossetto, Ivica Matak   +6 more
wiley   +1 more source

Rab6-Mediated Polarized Transport of Synaptic Vesicle Precursors Is Essential for the Establishment of Neuronal Polarity and Brain Formation. [PDF]

J Neurosci
Zhang Y, Kunii M, Taniguchi M, Yoshimura SI, Harada A.   +4 more
europepmc   +1 more source

Synaptic vesicle glycoprotein 2C enhances vesicular storage of dopamine and counters dopaminergic toxicity. [PDF]

Eur J Neurosci
Bucher ML, Dunn AR, Bradner JM, Egerton KS, Burkett JP, Johnson MA, Miller GW.   +6 more
europepmc   +1 more source