Results 1 to 10 of about 65,102 (185)
Melatonin as an Alleviator in Decabromodiphenyl Ether-Induced Aberrant Hippocampal Neurogenesis and Synaptogenesis: The Role of Wnt7a [PDF]
BiomoleculesDevelopmental exposure to polybrominated diphenyl ethers (PBDEs), which are commonly used as flame retardants, results in irreversible cognitive impairments.
Jinghua Shen +9 more
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Phytohormone Abscisic Acid Improves Spatial Memory and Synaptogenesis Involving NDR1/2 Kinase in Rats [PDF]
Frontiers in Pharmacology, 2018 The abscisic acid (ABA) is a phytohormone involved in plant growth, development and environmental stress response. Recent study showed ABA can also be detected in other organisms, including mammals.
Juanjuan Liu +6 more
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Nerve, Muscle, and Synaptogenesis
Cells, 2019 The vertebrate skeletal neuromuscular junction (NMJ) has long served as a model system for studying synapse structure, function, and development. Over the last several decades, a neuron-specific isoform of agrin, a heparan sulfate proteoglycan, has been ...
Lauren Eric Swenarchuk
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MiR-92 Controls Synaptic Development Through Glial Vha55 Regulation [PDF]
BiomoleculesMicroRNAs (miRNAs) have emerged as important biomarkers for complex neurological conditions. Modifications in synaptic morphology characterize several of these disease states, indicating a possible role of miRNA in modulating synaptic formation and ...
Simon M. Moe +4 more
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Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin-1 Loss. [PDF]
Aging CellErcoli S +3 more
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Molecular mechanisms of synaptogenesis
Frontiers in Synaptic Neuroscience, 2022 Synapses are the basic units for information processing and storage in the nervous system. It is only when the synaptic connection is established, that it becomes meaningful to discuss the structure and function of a circuit.
Cai Qi +4 more
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Frontiers in Cell and Developmental Biology, 2022 Lynx1 is a glycosylphosphatidylinositol (GPI)-linked protein shown to affect synaptic plasticity through modulation of nicotinic acetylcholine receptor (nAChR) subtypes in the brain.
Sydney V. Doss +11 more
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A splice isoform of DNedd4, DNedd4-long, negatively regulates neuromuscular synaptogenesis and viability in Drosophila. [PDF]
PLoS ONE, 2011 Neuromuscular (NM) synaptogenesis is a tightly regulated process. We previously showed that in flies, Drosophila Nedd4 (dNedd4/dNedd4S) is required for proper NM synaptogenesis by promoting endocytosis of commissureless from the muscle surface, a pre ...
Yunan Zhong +5 more
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Cell Reports, 2021 Summary: The mechanisms controlling the post-natal maturation of astrocytes play a crucial role in ensuring correct synaptogenesis. We show that mitochondrial biogenesis in developing astrocytes is necessary for coordinating post-natal astrocyte ...
Tamara Zehnder +8 more
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Astrocyte-Neuron Signaling in Synaptogenesis
Frontiers in Cell and Developmental Biology, 2021 Astrocytes are the key component of the central nervous system (CNS), serving as pivotal regulators of neuronal synapse formation and maturation through their ability to dynamically and bidirectionally communicate with synapses throughout life.
Lili Shan +9 more
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