Results 21 to 30 of about 63,572 (265)
Chemogenetic manipulation of astrocyte activity at the synapse— a gateway to manage brain disease
Astrocytes are the major glial cell type in the central nervous system (CNS). Initially regarded as supportive cells, it is now recognized that this highly heterogeneous cell population is an indispensable modulator of brain development and function ...
Maria João Pereira +6 more
doaj +1 more source
Presynaptic partner selection during retinal circuit reassembly varies with timing of neuronal regeneration in vivo [PDF]
Whether neurons can restore their original connectivity patterns during circuit repair is unclear. Taking advantage of the regenerative capacity of zebrafish retina, we show here the remarkable specificity by which surviving neurons reassemble their ...
A Carleton +49 more
core +1 more source
Correlation with basic differentiation processes of neurons [PDF]
The development of the spinal cord involves the proliferation of neurons, their migration to well-defined areas, fiber outgrowth and synapse formation. The present study was designed to correlate the spatiotemporal pattern of expression of synaptophysin,
Altman +37 more
core +2 more sources
Response of Astrocyte Subpopulations Following Spinal Cord Injury
There is growing appreciation for astrocyte heterogeneity both across and within central nervous system (CNS) regions, as well as between intact and diseased states. Recent work identified multiple astrocyte subpopulations in mature brain. Interestingly,
R. Vivian Allahyari +9 more
doaj +1 more source
Putative cell adhesion membrane protein Vstm5 regulates neuronal morphology and migration in the central nervous system [PDF]
During brain development, dynamic changes in neuronal membranes perform critical roles in neuronal morphogenesis and migration to create functional neural circuits.
Ko, Kwang Woo +5 more
core +2 more sources
Involvement of JNK1 in Neuronal Polarization During Brain Development
The c-Jun N-terminal Kinases (JNKs) are a group of regulatory elements responsible for the control of a wide array of functions within the cell. In the central nervous system (CNS), JNKs are involved in neuronal polarization, starting from the cell ...
Rubén Darío Castro-Torres +9 more
doaj +1 more source
Morphological plasticity of astroglia: Understanding synaptic microenvironment [PDF]
Memory formation in the brain is thought to rely on the remodeling of synaptic connections which eventually results in neural network rewiring. This remodeling is likely to involve ultrathin astroglial protrusions which often occur in the immediate ...
Heller, JP, Rusakov, DA
core +1 more source
Nerve, Muscle, and Synaptogenesis [PDF]
The vertebrate skeletal neuromuscular junction (NMJ) has long served as a model system for studying synapse structure, function, and development. Over the last several decades, a neuron-specific isoform of agrin, a heparan sulfate proteoglycan, has been identified as playing a central role in synapse formation at all vertebrate skeletal neuromuscular ...
openaire +5 more sources
Episodic memory: neurological and neuromediator mechanisms
Significant advances in understanding of neurological and neuromediatormechanisms of memory along with the causes ofmemory decline in aging were achieved recently.
A. G. Polunina, E. A. Bryun
doaj +1 more source
Summary: Neuronal synapse formation is critical for brain development and depends on secreted factors from astrocytes. Here, we report that small extracellular vesicles (EVs) secreted from primary astrocytes, but not from neurons or C6 glioma cells ...
Mikin R. Patel, Alissa M. Weaver
doaj +1 more source

