Results 141 to 150 of about 32,650 (238)

Interaction of Stoned and Synaptotagmin in Synaptic Vesicle Endocytosis

, 2001
TheDrosophiladicistronicstonedlocus encodes two distinctive presynaptic proteins, Stoned A (STNA) and Stoned B (STNB); STNA is a novel protein without homology to known synaptic proteins, and STNB contains a domain with homology to the endocytotic ...
Kendal Broadie, Tim Fergestad
core   +1 more source

Synaptotagmin I and IV define distinct populations of neuronal transport vesicles.

, 2017
Mammalian synaptotagmins constitute a multigene family of at least 11 membrane proteins. We have characterized synaptotagmin IV using antibodies directed against the C2A domain of the protein.
Dargent, Bénédicte, Seagar, Michael, Berton, Frédérique, Fukuda, Mitsunori, Marquèze, Béatrice, Cornet, Véronique, Garrido Jurado, Juan José, Iborra, Cécile   +7 more
core   +1 more source

Competition Between Synaptotagmin 1 and Complexin for SNARE Complex Binding, Controls Fast Synaptic Vesicle Exocytosis [PDF]

, 2007
Calcium binding to synaptotagmin 1 triggers fast exocytosis of synaptic vesicles that were primed for release by SNARE complex assembly. Besides synaptotagmin 1, fast Ca2+- triggered exocytosis requires complexins.
Tang, Jiong
core   +1 more source

Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis

, 2000
Synaptotagmin is involved in Ca2+-regulated secretion and has been suggested to serve as a general Ca2+ sensor on the membrane of secretory vesicles in neuronal cells.
Rhodes, C J, Seino, S, Brown, H, Corkey, B E, Larsson, O, Fried, G, Meister, B, Deeney, J, Berggren, P O, Yang, S N   +9 more
core   +1 more source

Increased expression of SNARE proteins and synaptotagmin IV in islets from pregnant rats and in vitro prolactin-treated neonatal islets

Biological Research, 2006
During pregnancy and the perinatal period of life, prolactin (PRL) and other lactogenic substances induce adaptation and maturation of the stimulus-secretion coupling system in pancreatic β-cells. Since the SNARE molecules, SNAP-25, syntaxin 1, VAMP-
DANIEL A CUNHA, MARIA EC AMARAL, CAROLINA PF CARVALHO, CARLA B COLLARES-BUZATO, EVERARDO M CARNEIRO, ANTONIO C BOSCHERO   +5 more
doaj  

Synaptotagmin I functions as a calcium regulator of release probability.

, 2001
In all synapses, Ca2+ triggers neurotransmitter release to initiate signal transmission. Ca2+ presumably acts by activating synaptic Ca2+ sensors, but the nature of these sensors-which are the gatekeepers to neurotransmission-remains unclear.
Gerber, S. H., Suedhof, T., Nils Brose, Garcia, J, Fernandez-Chacon, R., Jesús García, Charles F. Stevens, Rizo, J., Andreas Königstorfer, Christian Rosenmund, Suedhof, T. C., Rizo, Josep, Matos, M., Koenigstorfer, A., Josep Rizo, Thomas C. Südhof, Stevens, C., Stefan H. Gerber, Garcia, J., Maria F. Matos, Fernandez-Chacon, R, Gerber, S., Stevens, C. F., Königstorfer, A., Brose, Nils, Suedhof, Thomas C., Brose, N., Rosenmund, C., Rafael Fernández-Chacón, Matos, M. F.   +29 more
core   +1 more source

Calcium sensing by C2A domain of Synaptotagmin 7 is required through the linker for both synaptic facilitation and memory

Akira Sakurai, Takaaki Fujii, Motojiro Yoshihara   +2 more
openalex   +2 more sources

Author response: Synaptotagmin 1 and Synaptotagmin 7 promote MR1-mediated presentation of Mycobacterium tuberculosis antigens [PDF]

Se-Jin Kim, Jessie C. Peterson, Andrew J. Olive, Fikadu Tafesse, Corinna A. Kulicke, Elham Karamooz, David M. Lewinsohn   +6 more
openalex   +2 more sources

lncRNA <i>TUG1</i> mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes. [PDF]

Int J Mol Med
Wei YD, Chen PQ, Zheng X, Wu LQ, Wang XY, Gao XR, Ge JF.   +6 more
europepmc   +1 more source

Unraveling the Functions of Synaptotagmin and Munc13 in Neurotransmitter Release

, 2015
Neurotransmitter release is a central event in interneuronal communication. The release machinery includes three SNAREs (soluble N-ethylmaleimide sensitive factor adaptor protein receptor) and Munc18-1 as core components.
Seven, Alpay Burak
core