Results 51 to 60 of about 24,713 (214)
Arteriosclerosis, Thrombosis, and Vascular Biology, 2009 Objective— Arterial injury induces smooth muscle cell (SMC) proliferation, migration, and intimal accumulation of cells and extracellular matrix. These processes are regulated by the administration of the glycosaminoglycans heparin and heparan sulfate, but little is known about the role of endogenous
Nozomi, Fukai +5 more
openaire +2 more sources
Molecular targets and signaling pathways regulated by nuclear translocation of syndecan-1
BMC Cell Biology, 2017 Background The cell-surface heparan sulfate proteoglycan syndecan-1 is important for tumor cell proliferation, migration, and cell cycle regulation in a broad spectrum of malignancies.
Tünde Szatmári +6 more
doaj +1 more source
A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure [PDF]
, 2017 Aims: It is unclear whether distinct pathophysiological processes are present among patients with acute heart failure (AHF), with and without diabetes.
Bloomfield, Daniel M. +17 more
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PLoS ONE, 2009 BackgroundLung injury promotes the expression of matrix metalloproteinase-7 (MMP7, matrilysin), which is required for neutrophil recruitment and re-epithelialization. MMP7 governs the lung inflammatory response through the shedding of syndecan-1. Because
Peter Chen +5 more
doaj +1 more source
On Top of the Alveolar Epithelium: Surfactant and the Glycocalyx [PDF]
, 2020 Gas exchange in the lung takes place via the air-blood barrier in the septal walls of alveoli. The tissue elements that oxygen molecules have to cross are the alveolar epithelium, the interstitium and the capillary endothelium.
Hegermann, Jan +8 more
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Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells
Cell Communication and Signaling, 2020 Background Syndecans regulate cell migration thus having key roles in scarring and wound healing processes. Our previous results have shown that Thy-1/CD90 can engage both αvβ3 integrin and Syndecan-4 expressed on the surface of astrocytes to induce cell
Alejandra Valdivia +11 more
doaj +1 more source
PLoS ONE, 2021 Syndecan-1 is found in the endothelial glycocalyx and is released into the bloodstream during stressed conditions, including severe diseases such as acute kidney injury, chronic kidney disease, and cardiovascular disease.
Yuichiro Kitagawa +29 more
doaj +3 more sources
Syndecan expressions in the human amnion and chorionic plate
European Journal of Histochemistry, 2010 The syndecan family consists of four distinct membrane glycoproteins in mammals. Syndecans control cell proliferation, differentiation, adhesion and migration through participation in cell-cell interactions, anchorage of cells to the extracellular ...
T. Lorenzi +7 more
doaj +1 more source
Osteoprotegerin Contributes to the Metastatic Potential of Cells with a Dysfunctional TSC2 Tumor-Suppressor Gene [PDF]
, 1974 In addition to its effects on bone metabolism, osteoprotegerin (OPG), a soluble member of the tumor necrosis factor family of receptors, promotes smooth muscle cell proliferation and migration and may act as a survival factor for tumor cells.
Steagall, Wendy K. +6 more
core +1 more source
ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis [PDF]
, 2005 Members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family are known to influence development, angiogenesis, coagulation and progression of arthritis.
Jones, GC, Riley, GP
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