Results 81 to 90 of about 11,302 (215)
The endothelial glycocalyx in syndecan-1 deficient mice [PDF]
Microvascular Research, 2013 The existence of a hydrodynamically relevant endothelial glycocalyx has been established in capillaries, venules, and arterioles in vivo. The glycocalyx is thought to consist primarily of membrane-bound proteoglycans with glycosaminoglycan side-chains, membrane-bound glypicans, and adsorbed plasma proteins.
John Jiang +3 more
openaire +3 more sources
Heparan sulfate mediates trastuzumab effect in breast cancer cells [PDF]
, 2013 Background: Trastuzumab is an antibody widely used in the treatment of breast cancer cases that test positive for the human epidermal growth factor receptor 2 (HER2).
Del Giglio, Auro +5 more
core +2 more sources
Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby
Developmental Dynamics, EarlyView.Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe +3 more
wiley +1 more source
Differences in E-Cadherin and Syndecan-1 Expression in Different Types of Ameloblastomas
Analytical Cellular Pathology, 2018 Ameloblastomas are a group of benign, locally aggressive, recurrent tumors characterized by their slow and infiltrative growth. E-Cadherin and syndecan-1 are cell adhesion molecules related to the behavior of various tumors, including ameloblastomas ...
Ramón G. Carreón-Burciaga +5 more
doaj +1 more source
CD138 (syndecan-1) expression in health and disease.
Histology and histopathology, 2014 CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions. In adult human tissues, CD138 is predominantly expressed in epithelial cells and plasmacytes.
Dina Tiniakos +2 more
openaire +4 more sources
TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent [PDF]
, 2008 Toll-like receptor (TLR) signaling induces a rapid reorganization of the actin cytoskeleton in cultured mouse dendritic cells (DC), leading to enhanced antigen endocytosis and a concomitant loss of filamentous actin–rich podosomes.
Chan, Kui Ming +6 more
core +5 more sources
Developmental Dynamics, EarlyView.Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm +7 more
wiley +1 more source
Life, 2023 (1) Background: Acute heart failure (HF) represents a complex clinical syndrome burdened by increased mortality and a high rate of systemic complications.
Radu-Stefan Miftode +12 more
doaj +1 more source
Peripheral desmoplastic ameloblastoma : histopathological and immunohistochemical profile of a case [PDF]
, 2010 In this study we present a rare case of peripheral desmoplastic ameloblastoma and discuss its clinical features, histopathology, and inmunoshistochemical profile.
Almeida, Oslei Paes de +4 more
core +1 more source
Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines
Exploration, EarlyView.This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li +6 more
wiley +1 more source