Results 91 to 100 of about 50,065 (249)

The Chalcogen Exchange: The Replacement of Oxygen with Sulfur and Selenium to Boost the Activity of Natural Products

Sci
Antioxidants, such as stilbenes, anthocyanidins, coumarins, tannins and flavonoids, are often based on oxygen-containing redox systems and tend to feature several hydroxyl groups in their chemical structures.
Muhammad Jawad Nasim, Wesam Ali, Eufrânio N. da Silva Júnior, Rahman Shah Zaib Saleem, Caroline Gaucher, Jadwiga Handzlik, Silvana Pedatella, Claus Jacob   +7 more
doaj   +1 more source

Pharmacokinetic Assessment of Atazanavir and Favipiravir Following Echinacea Supplementation: A Controlled Herb–Drug Interaction Investigation

Biopharmaceutics &Drug Disposition, EarlyView.
Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula, Jeevan Sai Kallam, Aarika Kanukolanu, Ganesh Korada, Lakshmi Vineela Nalla   +4 more
wiley   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

Quercetin‐zinc coordination polymer coated CaCO3 nanoparticles potentiate radiotherapy through reprogramming tumor immunosuppression

BMEMat, EarlyView.
Synthesis of QZCaCO3‐PEG to synergistically enhance the immunogenicity of radiotherapy through concurrent Zn2+‐induced cancer cell pyroptosis and Que‐mediated hypoxia amelioration through sequentially suppressing TGF‐β secretion and ECM deposition. Abstract Radiotherapy has demonstrated broad applications in treating solid tumors, but the hostile tumor
Chunjie Wang, Hengze Ding, Yu Hao, Honglin An, Ziliang Dong, Minming Chen, Yujie Zhu, Quguang Li, Bin Huang, Liangzhu Feng   +9 more
wiley   +1 more source

Multifunctional polycaprolactone‐based composite fibers with icariin and glutathione for effective repair of critical‐sized bone defects

BMEMat, EarlyView.
A multifunctional PCL‐based scaffold co‐delivering Icariin and Glutathione synergistically enhances osteogenesis, angiogenesis, and oxidative stress resistance, achieving near‐complete repair of critical‐sized bone defects in vivo. This cell‐free platform represents a promising strategy for accelerated bone regeneration.
Abdurohman Mengesha Yessuf, Yaqi Zhang, Bharat Prasad Sharma, Yake Wang, Tibebu Shiferaw Kassa, Abdul Qadir, Ye Jinqiu, Mohamedazeem M. Mohideen, Ahmed M. Salama, Weiguo Wang, Qidong Zhang, Yong Liu   +11 more
wiley   +1 more source

Sunlight‐Driven Green Synthesis of Platinum Nanoparticles From Double‐Vacancy Halide Perovskite Precursors for Methanol Reforming

Chemistry – A European Journal, EarlyView.
Sunlight‐driven synthesis offers a green and energy‐efficient route to metallic nanoparticles. Here, double‐vacancy halide perovskites (Cs2PtX6, X = Cl, Br) act as photoactive precursors for the in‐situ formation of ultrasmall (< 3 nm) platinum nanoparticles under simulated sunlight at room temperature.
Kevin Mego, Saray Chacón‐Ruiz, Pedro Ruiz‐Campos, Herme G. Baldoví, Pedro Atienzar   +4 more
wiley   +1 more source

Systemically functional characterization of regiospecific flavonoid O-methyltransferases from Glycine max

Synthetic and Systems Biotechnology
Plants produce diverse flavonoids for defense and stress resistance, most of which have health benefits and are widely used as food additives and medicines.
Bingtong Feng, Yuguo Jiang, Xiaodong Li, Yan Wang, Ziyu Ren, Jian Lu, Xing Yan, Zhihua Zhou, Pingping Wang   +8 more
doaj   +1 more source

Natural Anthraquinone‐Like Compound Extracted from Green Husk of Walnut Improves Photocatalytic H2O2 Production Catalyzed by TiO2 Nanoparticles

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
In this work, a novel biomolecule/semiconductor hybrid catalyst was prepared by loading anthraquinone‐liked juglone onto anatase TiO2. This catalyst exhibited high photocatalytic activity for H2O2 production. Hydrogen peroxide (H2O2) is a vital oxidant with broad industrial applications, and its production via photocatalysis represents a highly ...
Zengyin He, Cui Li, Mingze Ni, Shu Lin, Kezhen Qi   +4 more
wiley   +1 more source

Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis

European Journal of Organic Chemistry, EarlyView.
In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley   +1 more source

Flavonoids, Chalcones, and Their Fluorinated Derivatives—Recent Advances in Synthesis and Potential Medical Applications

Molecules
Flavonoids and chalcones, widely recognised for their diverse biological activities, have garnered attention due to their potential therapeutic applications.
Jakub Kubiak, Piotr Szyk, Beata Czarczynska-Goslinska, Tomasz Goslinski   +3 more
doaj   +1 more source