Results 121 to 130 of about 52,872 (276)

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu, I. A. Anjola, L. O. Fasasi, D. P. Fadipe, A. T. Afuye, F. O. Fasanya, O. E. Oke   +6 more
wiley   +1 more source

Pharmacokinetic Assessment of Atazanavir and Favipiravir Following Echinacea Supplementation: A Controlled Herb–Drug Interaction Investigation

Biopharmaceutics &Drug Disposition, EarlyView.
Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula, Jeevan Sai Kallam, Aarika Kanukolanu, Ganesh Korada, Lakshmi Vineela Nalla   +4 more
wiley   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

Flavonoids as benign substitutes for more harmful synthetic chemicals - effects of flavonoids and their transformation products on algae

Sustainable Chemistry and Pharmacy
Flavonoids, a group of plant secondary metabolites, are seen as chemicals for pharmaceutical, nutraceutical, and pesticidal applications. Due to their natural origin, anticipated low ecotoxicity and non-persistence in the environment, they are considered as benign substitutes for synthetic chemicals.
Schnarr, Lena, Olsson, Oliver, Ohls, Sonia, Webersinn, Jolanda, Mauch, Tim, Kümmerer, Klaus   +5 more
openaire   +2 more sources

Protein hydrolysates in cell culture: Toward multi‐omics characterization

Biotechnology Progress, EarlyView.
While protein hydrolysates are widely used in cell culture applications, they remain undefined and variable products. Multi‐omic characterization evaluating composition and function can transition hydrolysates toward semi‐defined media components.
Michelle Combe, Brandon M. Wrage, Angel Varela‐Rohena, Stanislav Sokolenko   +3 more
wiley   +1 more source

Systemically functional characterization of regiospecific flavonoid O-methyltransferases from Glycine max

Synthetic and Systems Biotechnology
Plants produce diverse flavonoids for defense and stress resistance, most of which have health benefits and are widely used as food additives and medicines.
Bingtong Feng, Yuguo Jiang, Xiaodong Li, Yan Wang, Ziyu Ren, Jian Lu, Xing Yan, Zhihua Zhou, Pingping Wang   +8 more
doaj   +1 more source

Comparative Effects of White and Black Garlic on the Technological, Nutritional, and Sensory Properties of White and Whole Wheat Bread

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives The response of bread systems to ingredient enrichment varies depending on flour composition and matrix structure. This study investigated the impact of white garlic (WG) and black garlic (BG) enrichment (1%–7%) on the technological properties, composition, antioxidants, and sensory characteristics of refined white ...
Derya Ozalp Unal, Aliye Pehlivan, Yeliz Kaya Kartal, Arzu Ozer, Seda Kulen   +4 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Sunlight‐Driven Green Synthesis of Platinum Nanoparticles From Double‐Vacancy Halide Perovskite Precursors for Methanol Reforming

Chemistry – A European Journal, EarlyView.
ABSTRACT The development of synthetic procedures for preparing metal nanoparticles with controlled size using sunlight opens new avenues toward more sustainable methods with lower energy consumption. Herein, we propose the use of double‐vacancy halide perovskites as precursors for engineering highly crystalline and small platinum nanoparticles (< 3 nm)
Kevin Mego, Saray Chacón‐Ruiz, Pedro Ruiz‐Campos, Herme G. Baldoví, Pedro Atienzar   +4 more
wiley   +1 more source

Clinical development and informatics analysis of natural and semi-synthetic flavonoid drugs: A critical review

Journal of Advanced Research
Background: Flavonoids are one of the most important metabolites with vast structural diversity and a plethora of potential pharmacological applications, which have drawn considerable attention in the laboratory.
Kuo Xu, Xia Ren, Jintao Wang, Qin Zhang, Xianjun Fu, Pei-Cheng Zhang   +5 more
doaj   +1 more source