Results 131 to 140 of about 52,872 (276)

Highly Potent Fluorogenic Ligands for Triplex DNA: 5‐Substituted 2‐(Naphthalen‐2‐yl)‐4H‐Chromen‐4‐Ones

Chemistry – A European Journal, EarlyView.
5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran, Landy Gu, Krege M. Christison, Kalee Thao, Liang Xue   +4 more
wiley   +1 more source

Flavonoids, Chalcones, and Their Fluorinated Derivatives—Recent Advances in Synthesis and Potential Medical Applications

Molecules
Flavonoids and chalcones, widely recognised for their diverse biological activities, have garnered attention due to their potential therapeutic applications.
Jakub Kubiak, Piotr Szyk, Beata Czarczynska-Goslinska, Tomasz Goslinski   +3 more
doaj   +1 more source

Natural Anthraquinone‐Like Compound Extracted from Green Husk of Walnut Improves Photocatalytic H2O2 Production Catalyzed by TiO2 Nanoparticles

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
In this work, a novel biomolecule/semiconductor hybrid catalyst was prepared by loading anthraquinone‐liked juglone onto anatase TiO2. This catalyst exhibited high photocatalytic activity for H2O2 production. Hydrogen peroxide (H2O2) is a vital oxidant with broad industrial applications, and its production via photocatalysis represents a highly ...
Zengyin He, Cui Li, Mingze Ni, Shu Lin, Kezhen Qi   +4 more
wiley   +1 more source

Morus alba Linn. leaf as a food and drug homologs: chemical composition and structure, biological activity, mechanism of action, research progress on its biosynthetic pathway, and application challenges in future food

Journal of Agriculture and Food Research
Mulberry (Morus alba L.) leaf, recognized as a traditional Chinese medicine, plays an important role in both food and pharmaceutical applications owing to its distinctive medicinal-food homology properties.
Yanhui Yi, Hengyu Lv, Yuhua Wang, Feng Zhao, Jianzeng Xin, Sheng Liu   +5 more
doaj   +1 more source

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini, Arunachalam Divya, Kumar Sowndharya, Parthiban Jeevitha, Selvam Manoj, Ashiq Rahman, Athil Ahamed, Ravichandiran Abirahul, Paranthaman Subash, Sulekha Khute   +9 more
wiley   +1 more source

Flavonoids: Antioxidant Powerhouses and Their Role in Nanomedicine

This study emphasizes the critical role of antioxidants in protecting human health by counteracting the detrimental effects of oxidative stress induced by free radicals.
Mehak Zahra, Blassan P. George, Heidi Abrahamse   +2 more
core   +1 more source

Fermentation‐Induced Modulation of Polyphenolic Contents and Medicinal Activities in Annona squamosa Seeds

Food Chemistry International, EarlyView.
The study compared the medicinal activities of polyphenols from fermented and unfermented seeds of Annona squamosa. The polyphenols were extracted and subjected to standard analysis. The major phenolic components of the fermented polyphenols and the unfermented polyphenols were found to be 4‐hydroxybenzoic and 4‐hydroxyphenylacetic acid, respectively ...
Shola Hezekiah Awojide, Abayomi Gideon Adeyemo, Christianah Dare, Oluseye Oladapo Abiona, Adedayo Olubunmi Adeboye, Omolara Oladipo‐Olalekan, Aminat Adebola Adeyemo, Yemisi Elizabeth Asibor, Emmanuel Oluwafemi Adeniyi, Bunmi Regina Bankole, Ezekiel Olumide Fadunmade   +10 more
wiley   +1 more source

A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation

Food Chemistry International, EarlyView.
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee, Tien‐Fen Kuo, Chun‐Yen Yang, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source

Potential of Bee Pollen as a Nutraceutical And/Or Functional Ingredient for Metabolic Syndrome Management: In Vitro Antioxidant, Anti‐Inflammatory, and Digestive Enzyme Inhibitory Activities

Food Chemistry International, EarlyView.
Bee pollen samples from China and Spain exhibited in vitro antioxidant, anti‐inflammatory, and digestive enzyme inhibitory activities due to their composition, suggesting their potential as a nutraceutical or functional ingredient to help counteract oxidative stress, chronic inflammation, and metabolic disorders.
Adriana Maite Fernández‐Fernández, Victoria Olt, Jessica Báez, Marcelo Miraballes, Melissa Romero, Cecilia Dauber, Ignacio Vieitez, Estela Santos, Adriana Gámbaro, Alejandra Medrano   +9 more
wiley   +1 more source

Ultrasonic-Assisted Ginkgo biloba Leaves Extract as Natural Antioxidant on Oxidative Stability of Oils During Deep-Frying

Foods
Ginkgo biloba leaf flavonoids, while demonstrating antioxidant potential, remain underexplored as natural stabilizers for frying oils under thermo-oxidative stress.
Min Kang, Musfirah Zulkurnain
doaj   +1 more source