Results 11 to 20 of about 90,996 (204)

Synthetic flavonoids with antimicrobial activity: a review [PDF]

Journal of Applied Microbiology, 2019
The emergence of drug-resistant microbes left us with a great need for new antimicrobial agents. Flavonoids, with their wide range of biological activities, are good candidates in this respect. Although naturally occurring flavonoids are the most studied ones, semi-synthetic or synthetic flavonoids have proven to have great potential, inhibiting and ...
L.G. Sarbu, L.G. Bahrin, C. Babii, M. Stefan, M.L. Birsa   +4 more
openaire   +4 more sources

Inhibition of UGT1A1 by natural and synthetic flavonoids [PDF]

International Journal of Biological Macromolecules, 2019
Flavonoids are widely distributed phytochemicals in vegetables, fruits and medicinal plants. Recent studies demonstrate that some natural flavonoids are potent inhibitors of the human UDP-glucuronosyltransferase 1A1 (UGT1A1), a key enzyme in detoxification of endogenous harmful compounds such as bilirubin.
Liu, Xin-Yu, Lv, Xia, Wang, Ping, Ai, Chun-Zhi, Zhou, Qi-Hang, Finel, Moshe, Fan, Bin, Cao, Yun-Feng, Tang, Hui, Ge, Guang-Bo   +9 more
openaire   +5 more sources

Photochemistry of Flavonoids

Molecules, 2010
Flavonoids and their photochemical transformations play an important role in biological processes in nature. Synthetic photochemistry allows access to molecules that cannot be obtained via more conventional methods.
Jan H. Van der Westhuizen, Susan L. Bonnet, Daneel Ferreira, Miroslav Sisa   +3 more
doaj   +3 more sources

Review of the antioxidant potential of flavonoids as a subgroup of polyphenols and partial substitute for synthetic antioxidants [PDF]

Avicenna Journal of Phytomedicine, 2023
Objective: This review describes the antioxidant activity of flavonoids as a subgroup of polyphenols and a partial or entire substitute for synthetic antioxidants.Materials and Methods: All relevant databases were searched using the terms “Phytochemical”,
Seyyed Hossein Hassanpour, Alireza Doroudi   +1 more
doaj   +1 more source

Preparation of Synthetic and Natural Derivatives of Flavonoids Using Suzuki–Miyaura Cross-Coupling Reaction

Molecules, 2022
Herein, we report the use of the Suzuki–Miyaura cross-coupling reaction for the preparation of a library of synthetic derivatives of flavonoids for biological activity assays.
Martina Hurtová, David Biedermann, Zuzana Osifová, Josef Cvačka, Kateřina Valentová, Vladimír Křen   +5 more
doaj   +1 more source

Systematic exploration of natural and synthetic flavonoids for the inhibition of Staphylococcus aureus biofilms. [PDF]

Int J Mol Sci, 2013
Manner S, Skogman M, Goeres D, Vuorela P, Fallarero A.   +4 more
europepmc   +2 more sources

Chiral Flavonoids as Antitumor Agents

Pharmaceuticals, 2021
Flavonoids are a group of natural products with a great structural diversity, widely distributed in plant kingdom. They play an important role in plant growth, development and defense against aggressors.
Cláudia Pinto, Honorina Cidade, Madalena Pinto, Maria Elizabeth Tiritan   +3 more
doaj   +1 more source

Plant Flavonoid Production in Bacteria and Yeasts

Frontiers in Chemical Engineering, 2022
Flavonoids, a major group of secondary metabolites in plants, are promising for use as pharmaceuticals and food supplements due to their health-promoting biological activities. Industrial flavonoid production primarily depends on isolation from plants or
Shota Isogai, Shota Isogai, Masahiro Tominaga, Masahiro Tominaga, Akihiko Kondo, Akihiko Kondo, Akihiko Kondo, Akihiko Kondo, Akihiko Kondo, Jun Ishii, Jun Ishii, Jun Ishii   +11 more
doaj   +1 more source

Natural and synthetic flavonoid modulation of TRPC5 channels [PDF]

British Journal of Pharmacology, 2016
Background and PurposeThe TRPC5 proteins assemble to create calcium‐permeable, non‐selective, cationic channels. We sought novel modulators of these channels through studies of natural products.Experimental ApproachIntracellular calcium measurements and patch clamp recordings were made from cell lines.
Naylor, J, Minard, A, Gaunt, HJ, Amer, MS, Wilson, LA, Migliore, M, Cheung, SY, Rubaiy, H, Blythe, NM, Musialowski, KE, Ludlow, MJ, Evans, WD, Green, BL, Yang, H, You, Y, Li, J, Fishwick, CWG, Muraki, K, Beech, DJ, Bon, RS   +19 more
openaire   +3 more sources

Synthetic Biology’s Latest Trends in Antimicrobial Resistance and Biofilm

Journal of Pure and Applied Microbiology, 2023
Recent instances of novel biological circuits that enable cells to gain biosynthetic skills demonstrate synthetic biology’s therapeutic potential. Synthetic biology is a branch of biology whose primary role is to build completely functional biological ...
P.A. Aboobacker, Latha Ragunathan, Thiyagarajan Sanjeevi, Aarthi Manoharan, Aravind C. Sasi, Vishnu Chandran, Kavitha Kannaiyan, Marcella Sherin Samuel   +7 more
doaj   +1 more source