Results 21 to 30 of about 52,872 (276)

Nephroprotective Effects of Synthetic Flavonoid Hidrosmin in Experimental Diabetic Nephropathy [PDF]

Antioxidants, 2021
Diabetes mellitus (DM) is a high-impact disease commonly characterized by hyperglycemia, inflammation, and oxidative stress. Diabetic nephropathy (DN) is a common diabetic microvascular complication and the leading cause of chronic kidney disease worldwide.
Luna Jiménez-Castilla, Gema Marín-Royo, Macarena Orejudo, Lucas Opazo-Ríos, Teresa Caro-Ordieres, Inés Artaiz, Tatiana Suárez-Cortés, Arturo Zazpe, Gonzalo Hernández, Carmen Gómez-Guerrero, Jesús Egido   +10 more
openaire   +4 more sources

Review of the antioxidant potential of flavonoids as a subgroup of polyphenols and partial substitute for synthetic antioxidants [PDF]

Avicenna Journal of Phytomedicine, 2023
Objective: This review describes the antioxidant activity of flavonoids as a subgroup of polyphenols and a partial or entire substitute for synthetic antioxidants.Materials and Methods: All relevant databases were searched using the terms “Phytochemical”,
Seyyed Hossein Hassanpour, Alireza Doroudi   +1 more
doaj   +1 more source

Plant Flavonoid Production in Bacteria and Yeasts

Frontiers in Chemical Engineering, 2022
Flavonoids, a major group of secondary metabolites in plants, are promising for use as pharmaceuticals and food supplements due to their health-promoting biological activities. Industrial flavonoid production primarily depends on isolation from plants or
Shota Isogai, Shota Isogai, Masahiro Tominaga, Masahiro Tominaga, Akihiko Kondo, Akihiko Kondo, Akihiko Kondo, Akihiko Kondo, Akihiko Kondo, Jun Ishii, Jun Ishii, Jun Ishii   +11 more
doaj   +1 more source

Natural and synthetic flavonoid modulation of TRPC5 channels [PDF]

British Journal of Pharmacology, 2016
Background and PurposeThe TRPC5 proteins assemble to create calcium‐permeable, non‐selective, cationic channels. We sought novel modulators of these channels through studies of natural products.Experimental ApproachIntracellular calcium measurements and patch clamp recordings were made from cell lines.
Naylor, J, Minard, A, Gaunt, HJ, Amer, MS, Wilson, LA, Migliore, M, Cheung, SY, Rubaiy, H, Blythe, NM, Musialowski, KE, Ludlow, MJ, Evans, WD, Green, BL, Yang, H, You, Y, Li, J, Fishwick, CWG, Muraki, K, Beech, DJ, Bon, RS   +19 more
openaire   +4 more sources

Anti-Candida activity of flavonoids - an overview

Journal of Experimental and Molecular Biology, 2023
Flavonoids are a group of plant polyphenols which received an increased attention during the recent past due to their important antimicrobial activities.
Savu Mihaela, Marius Stefan
doaj   +1 more source

Fig. 9 in A comprehensive review: Biological activity, modification and synthetic methodologies of prenylated flavonoids

, 2021
Fig. 9. Chemical structures of prenylated flavonoids with anti-inflammation (273–368).Published as part of Shi, Shaochun, Li, Jichong, Zhao, Xuemei, Liu, Qingbo & Song, Shao-Jiang, 2021, A comprehensive review: Biological activity, modification and ...
Liu, Qingbo, Shi, Shaochun, Li, Jichong, Zhao, Xuemei, Song, Shao-Jiang   +4 more
core   +3 more sources

Repositioning microbial biotechnology against COVID‐19: the case of microbial production of flavonoids

Microbial Biotechnology, 2021
Summary Coronavirus‐related disease 2019 (COVID‐19) became a pandemic in February 2020, and worldwide researchers try to tackle the disease with approved drugs of all kinds, or to develop novel compounds inhibiting viral spreading.
Tobias Goris, Álvaro Pérez‐Valero, Igor Martínez, Dong Yi, Luis Fernández‐Calleja, David San León, Uwe T. Bornscheuer, Patricia Magadán‐Corpas, Felipe Lombó, Juan Nogales   +9 more
doaj   +1 more source

EVALUATION OF POTENTIAL ANTIMICROBIAL ACTIVITY OF SYNTHETIC FLAVONOIDS

Journal of Biomedical and Pharmaceutical Research, 2021
Introduction: In recent times, most of the currently available antimicrobial agents have developed resistance. Extensive pharmacological activities including bactericidal and bacteriostatic nature of flavonoids, made them as priority agents in this aspect of research study.
Prabhulingayya S Bhixavatimath, Yasmeen Maniyar, Akram Naikawadi, null Vijayakumar D   +3 more
openaire   +2 more sources

A modular synthetic biology toolkit in streptomyces for flavonoids biosynthesis and cellular chassis engineering [PDF]

, 2022
Synthetic Biology of Natural Products Conference (3rd. 2022. Cancún, México)A library of modular plasmids has been created for flavonoids biosynthesis gene clusters (BGCs) assembly through Modular Cloning (MoClo) and Streptomyces genome edition via ...
Villar Granja, Claudio Jesús, Ye Huang, Suhui, Magadán Corpas, Patricia, Torres Bacete, Jesús, Nogales, Juan, Lombó Brugos, Felipe, Pérez Valero, Álvaro   +6 more
core  

Comprehensive Review of Recent Advances in Chiral A-Ring Flavonoid Containing Compounds: Structure, Bioactivities, and Synthesis

Molecules, 2023
Flavonoids are a group of natural polyphenolic substances that are abundant in vegetables, fruits, grains, and tea. Chiral A-ring-containing flavonoids are an important group of natural flavonoid derivatives applicable in a wide range of biological ...
Changyue Zhang, Yanzhi Liu, Xiaojing Liu, Xiaochuan Chen, Ruijiao Chen   +4 more
doaj   +1 more source