Biochemical evaluation of molecular parts for flavonoid production using plant synthetic biology
Frontiers in Plant ScienceAmong organisms on Earth, plants have the unique ability to produce a wide variety of biomolecules using soil nutrients, air, and solar energy. Therefore, plants are regarded as the most productive and cost-efficient bioreactors among living organisms ...
Hyo Lee +4 more
doaj +3 more sources
Nephroprotective Effects of Synthetic Flavonoid Hidrosmin in Experimental Diabetic Nephropathy [PDF]
Antioxidants, 2021 Diabetes mellitus (DM) is a high-impact disease commonly characterized by hyperglycemia, inflammation, and oxidative stress. Diabetic nephropathy (DN) is a common diabetic microvascular complication and the leading cause of chronic kidney disease worldwide.
Luna Jiménez-Castilla +10 more
openaire +4 more sources
Metabolic Engineering of Microbial Cell Factories for Biosynthesis of Flavonoids: A Review
Molecules, 2021 Flavonoids belong to a class of plant secondary metabolites that have a polyphenol structure. Flavonoids show extensive biological activity, such as antioxidative, anti-inflammatory, anti-mutagenic, anti-cancer, and antibacterial properties, so they are ...
Hanghang Lou +4 more
doaj +1 more source
Review of the antioxidant potential of flavonoids as a subgroup of polyphenols and partial substitute for synthetic antioxidants [PDF]
Avicenna Journal of Phytomedicine, 2023 Objective: This review describes the antioxidant activity of flavonoids as a subgroup of polyphenols and a partial or entire substitute for synthetic antioxidants.Materials and Methods: All relevant databases were searched using the terms “Phytochemical”,
Seyyed Hossein Hassanpour +1 more
doaj +1 more source
Systematic exploration of natural and synthetic flavonoids for the inhibition of Staphylococcus aureus biofilms. [PDF]
Int J Mol Sci, 2013 Manner S +4 more
europepmc +2 more sources
Molecules, 2022 Herein, we report the use of the Suzuki–Miyaura cross-coupling reaction for the preparation of a library of synthetic derivatives of flavonoids for biological activity assays.
Martina Hurtová +5 more
doaj +1 more source
Chiral Flavonoids as Antitumor Agents
Pharmaceuticals, 2021 Flavonoids are a group of natural products with a great structural diversity, widely distributed in plant kingdom. They play an important role in plant growth, development and defense against aggressors.
Cláudia Pinto +3 more
doaj +1 more source
Plant Flavonoid Production in Bacteria and Yeasts
Frontiers in Chemical Engineering, 2022 Flavonoids, a major group of secondary metabolites in plants, are promising for use as pharmaceuticals and food supplements due to their health-promoting biological activities. Industrial flavonoid production primarily depends on isolation from plants or
Shota Isogai +11 more
doaj +1 more source
Natural and synthetic flavonoid modulation of TRPC5 channels [PDF]
British Journal of Pharmacology, 2016 Background and PurposeThe TRPC5 proteins assemble to create calcium‐permeable, non‐selective, cationic channels. We sought novel modulators of these channels through studies of natural products.Experimental ApproachIntracellular calcium measurements and patch clamp recordings were made from cell lines.
Naylor, J +19 more
openaire +3 more sources
Synthetic Biology’s Latest Trends in Antimicrobial Resistance and Biofilm
Journal of Pure and Applied Microbiology, 2023 Recent instances of novel biological circuits that enable cells to gain biosynthetic skills demonstrate synthetic biology’s therapeutic potential. Synthetic biology is a branch of biology whose primary role is to build completely functional biological ...
P.A. Aboobacker +7 more
doaj +1 more source