Flavonoids – An Amazing Group of Compounds with Potent Antimicrobial Properties [PDF]
Memoirs of the Scientific Sections of the Romanian Academy, 2019 Antibiotic resistance is spreading all around the world, many infectious diseases are becoming more and more severe and sometimes impossible to treat, therefore new efficient solutions are desperately needed.
Marius Ștefan, Mihail Lucian Bîrsă
doaj
PARP Inhibition by Flavonoids Induced Selective Cell Killing to BRCA2-Deficient Cells
Pharmaceuticals, 2017 High consumption of dietary flavonoids might contribute to a reduction of cancer risks. Quercetin and its glycosides have PARP inhibitory effects and can induce selective cytotoxicity in BRCA2-deficient cells by synthetic lethality.
Cathy Su +4 more
doaj +1 more source
Inhibition of MurA Enzyme from Escherichia coli by Flavonoids and Their Synthetic Analogues
ACS Omega, 2023 MurA catalyzes the first step of peptidoglycan (PG) biosynthesis and is a validated target for the development of new antimicrobial agents. In this study, a library of 49 plant flavonoids and their synthetic derivatives were evaluated for their inhibitory properties against MurA fromEscherichia coli.
Rok Frlan +2 more
openaire +4 more sources
Overview of Genus Prosopis Toxicity Reports and its Beneficial Biomedical Properties [PDF]
, 2016 Secondary plant metabolites are regarded as promising sources of plant-protecting substances and they are one of the most important lines of plant defense against pests. The range of cellular targets for these substances is very wide and covers metabolic
Gamarra Luques, Carlos Diego +3 more
core +1 more source
Synthetic flavonoid dimers: Synthesis strategies and biological activities
European Journal of Medicinal ChemistryThe continuous search for novel and safer drug candidates remains imperative to address ever-evolving health challenges. Nature has long served as a source of inspiration for drug discovery, particularly through bioactive compounds such as flavonoids. Among them, flavonoid dimers, first identified nearly a century ago, have shown promising biological ...
Rui Pereira +3 more
openaire +2 more sources
Nutraceutical Properties and Toxicity Studies of Flour Obtained from Capsicum pubescens Fruits and Its Comparison with “Locoto” Commercial Powder [PDF]
, 2014 The aim of this research was to evaluate the phytochemical profiles of flour from red, yellow and green fruits of Capsicum pubescens (commun name: locoto) and compare with “locoto” commercial powder (Lcp).
Alberto, Maria Rosa +6 more
core +1 more source
Synthetic Approach to Chromone and Flavonoid Piperidine Alkaloids
The Journal of Organic ChemistryDespite the enormous importance of chromone and flavonoid piperidine alkaloids, a general method for their synthesis has not been described. Accordingly, from simple tetrahydro-3-pyridinemethanols (A) and phenol derivatives (B), a synthetic approach to chromone and flavonoid piperidine alkaloids is presented.
Karen A. Guarneros-Cruz +4 more
openaire +2 more sources
Predicting the composition of red wine blends using an array of Multicomponent peptide-based sensors [PDF]
, 2015 Differential sensing using synthetic receptors as mimics of the mammalian senses of taste and smell is a powerful approach for the analysis of complex mixtures.
Abdi +18 more
core +4 more sources