Results 91 to 100 of about 811,099 (302)

Novel Gel Techniques for Meloxicam Transdermal Administration as Topical Gel: A Systematic Review

International Journal of Pharmaceutical Research and Applications
A potential non-steroidal anti-inflammatory medication (NSAID) for the prevention and treatment of both acute and chronic pain is meloxicam. Meloxicam has limited therapeutic application because of its weak water solubility. Furthermore, it is challenging to develop a suitable NSAID-based delivery system that can pass through the skin barrier for ...
Deepak Kumar Pandey, Dr. Jai Narayan Mishra, Ashutosh Kushwaha, Dhaneshwar Kumar Vishwakarma   +3 more
openaire   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Job satisfaction in hotel employess: a systematic review of the literature [PDF]

, 2016
Hotel employees' job satisfaction is very important to their performance. In a systematic review of the previous literature on hotel employees, it was found that the most studied variable was job satisfaction; there were no other systematic reviews on ...
Borralha, Sérgio, Jesus, Saúl, Pinto, Patrícia, Viseu, J.   +3 more
core  

Interventions to improve hand hygiene compliance in patient care: Reflections on three systematic reviews for the Cochrane Collaboration 2007-2017 [PDF]

, 2018
This article presents highlights from a recently updated systematic Cochrane review evaluating the effectiveness of interventions to improve hand hygiene compliance in patient care.
Dinah Gould, Donna Moralejo, Gould DJ, Health Foundation, Jane Chudleigh, Monica Taljaard, Nicholas Drey, Pawson R, Sax H, Vernaz N   +9 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Mapping and systematic appraisal of umbrella reviews in epidemiological research: a protocol for a meta-epidemiological study

Systematic Reviews, 2023
Introduction Umbrella review is one of the terms used to describe an overview of systematic reviews. During the last years, a rapid increase in the number of umbrella reviews on epidemiological studies has been observed, but there is no systematic ...
Lazaros Belbasis, Robin D Brooker, Emmanuel Zavalis, Angelo Maria Pezzullo, Cathrine Axfors, John PA Ioannidis   +5 more
doaj   +1 more source

Simulation in manufacturing and business: A review [PDF]

, 2010
Copyright @ 2009 Elsevier B.V.This paper reports the results of a review of simulation applications published within peer-reviewed literature between 1997 and 2006 to provide an up-to-date picture of the role of simulation techniques within manufacturing
Aisha Naseer, Akkermans, Albino, Amoako-Gympah, Anderson, Antoniol, Arer, Arunachalam, Ashayeri, Ashworth, Ayag, Baines, Barman, Barton, Barua, Blocher, Bocker, Boel, Bosarth, Butler, Byrne, Cachon, Chan, Chan, Chan, Chatha, Chen, Chen, Christodoulou, Clark, De Ruyter, De Souza, De Treville, Durieux, Fleisch, Ford, Forssen, Gambardella, Giannini, Graham, Greasley, Greenhalgh, Grunow, Haas, Hahn, Hobbs, Hoesli, Hoogeweegen, Hueter, Hunt, Jacobson, Jahangirian, Jain, Jan, Kadipasaoglu, Kehris, Kellner, Kleijnen, Koh, Kwan, Kyamakya, Lainema, Lampros K. Stergioulas, Larsen, Lee, Lee, Lee, Lin, Lin, Liu, Love, Lukas, Lyneis, Lyneis, Lyneis, MacDonald, Machuca, Manzini, Marquez, Martin, McArthur, Mehra, Melao, Mendes, Mjema, Mohsen Jahangirian, Musselman, Nagano, Nance, Nass, Nassar, Noy, Olson, Orady, Otero-Novas, Owens, Pannirselvam, Park, Pfahl, Pfeil, Polat, Porter, Powell, Rabelo, Rabelo, Ranky, Reiner, Rodrigues, Rosen, Roser, Saltzman, Sawhney, Schwaninger, Schwartz, Shabayek, Shafer, Shafer, Shang, Smeds, Smith, Son, Spedding, Spengler, Sterman, Swain, Swaminathan, Taylor, Terry Young, Terzi, Theoharakis, Tillal Eldabi, Tofukuji, Van Der Vorst, Van Der Zee, Van Landeghem, Venkateswaran, Wenzler, Weston, Wolstenholme, Yan, Yazici, Yim, Zenios, Zha, Zulch, Zulch, Zülch   +146 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Canine Bacterial Endocarditis: A Text Mining and Topics Modeling Analysis as an Approach for a Systematic Review

Microorganisms
Bacterial endocarditis (BE) is a severe infection of the endocardium and cardiac valves caused by bacterial agents in dogs. Diagnosis of endocarditis is challenging due to the variety of clinical presentations and lack of definitive diagnostic tests in its early stages.
Previti, Annalisa, Biondi, Vito, Passantino, Annamaria, Or, Mehmet Erman, Pugliese, Michela   +4 more
openaire   +5 more sources