Results 71 to 80 of about 96,959 (285)

Combined Analysis of Transcriptome and T-Cell Receptor Alpha and Beta (TRA /TRB ) Repertoire in Paucicellular Samples at the Single-Cell Level. [PDF]

, 2022
With the advent of next-generation sequencing (NGS) methodologies, the total repertoires of B and T cells can be disclosed in much more detail than ever before.
Brouwer, Rutger W W, den Dekker, Xander, Langerak, Anton W, Azmani, Zakia, Betjes, Michiel G H, van IJcken, Wilfred F J; id_orcid, Litjens, Nicolle H R, van IJcken, Wilfred F J   +7 more
core   +1 more source

The T Cell Receptor Repertoire in Neuropsychiatric Systemic Lupus Erythematosus

Frontiers in Immunology, 2020
Objective: In systemic lupus erythematosus (SLE), widespread T cell infiltration into target organs contributes to inflammation and organ damage. Autoreactive T cells become aberrantly activated in this disease due to dysfunctional T cell receptor ...
Erica Moore, Michelle W. Huang, Shweta Jain, Samantha A. Chalmers, Fernando Macian, Chaim Putterman, Chaim Putterman, Chaim Putterman, Chaim Putterman   +8 more
doaj   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Oligoclonal expansions of CD8(+) T cells in chronic HIV infection are antigen specific

, 1998
Acute HIV infection is associated with a vigorous immune response characterized by the proliferation of selected T cell receptor V beta (BV)-expressing CD8(+) T cells.
Ogg, GS, Christopher A. O'Callaghan, Philip J.R. Goulder, O'Callaghan, CA, Allen, RL, Anthony Kelleher, Andy K. Sewell, Rowland-Jones, Sarah, Jamie D.K. Wilson, Kelleher, A, Mcmichael, Andrew, Goulder, PJ, Andrew J. McMichael, O'Callaghan, Christopher, Graham S. Ogg, Rachel L. Allen, Rowland-Jones, SL, Callan, MF, Wilson, JD, Sarah L. Rowland-Jones, Margaret F.C. Callan, Sewell, AK, McMichael, AJ   +22 more
core   +1 more source

IL-4 receptor expression on CD8+ T cells is required for the development of protective memory responses against liver stages of malaria parasites. [PDF]

, 2005
IL-4 receptor (IL-4R)-deficient CD8+ T cells specific for the circumsporozoite protein of Plasmodium yoelii develop a severely impaired memory response after priming with parasites.
Morrot, Alexandre, Alexandre Morrot, Fidel Zavala, Hafalla, Julius CR, Cockburn, Ian A, Carvalho, Luzia H, Zavala, Fidel, Julius C.R. Hafalla, Luzia H. Carvalho, Ian A. Cockburn   +9 more
core   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

The interferon alpha receptor utilises T-cell receptor-associated proteins for signalling [PDF]

, 2009
The interferon alpha receptor (IFNAR) and T-cell receptor (TCR) are expressed upon the T-cell surface. The dimeric Class I interferon receptor is a cytokine receptor that recognises interferons such as IFNα.
Stevens, C.N., Stevens, C N
core  

Impact of cellular lifespan on the T cell receptor repertoire [PDF]

European Journal of Immunology, 2007
AbstractPro‐survival members of the Bcl‐2 family are potent inhibitors of cell death and determine the lifespan of immature thymocytes by counteracting the intrinsically active apoptotic program in these cells. BH3‐only proteins are potent antagonists of Bcl‐2‐like molecules and regulate death and survival of lymphocytes during their development and ...
Abdelbasset, Hamrouni, Anna, Olsson, G Jan, Wiegers, Andreas, Villunger   +3 more
openaire   +2 more sources

Transducers Across Scales and Frequencies: A System‐Level Framework for Multiphysics Integration and Co‐Design

Advanced Materials Technologies, EarlyView.
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu, Mengyao Xiao, Zhouli Sui, Yinpeng Wang, Daoye Zheng, Yuxin Liu, Luwei Wang, Huajun Liu, Chengkuo Lee   +8 more
wiley   +1 more source

Potential role of HTLV-1 Tax-specific cytotoxic t lymphocytes expressing a unique t-cell receptor to promote inflammation of the central nervous system in myelopathy associated with HTLV-1

Frontiers in Immunology, 2022
Human T-lymphotropic virus 1 (HTLV-1) infection causes two serious diseases: adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy (HAM).
Yukie Tanaka, Yukie Tanaka, Tomoo Sato, Tomoo Sato, Naoko Yagishita, Junji Yamauchi, Junji Yamauchi, Natsumi Araya, Satoko Aratani, Satoko Aratani, Katsunori Takahashi, Yasuo Kunitomo, Misako Nagasaka, Misako Nagasaka, Yoshinobu Kanda, Yoshinobu Kanda, Kaoru Uchimaru, Kaoru Uchimaru, Tomohiro Morio, Yoshihisa Yamano, Yoshihisa Yamano   +20 more
doaj   +1 more source