Results 61 to 70 of about 1,940,376 (313)

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

MediMer: a versatile do-it-yourself peptide-receptive MHC class I multimer platform for tumor neoantigen-specific T cell detection

Frontiers in Immunology
Peptide-loaded MHC class I (pMHC-I) multimers have revolutionized our capabilities to monitor disease-associated T cell responses with high sensitivity and specificity.
Marten Meyer, Marten Meyer, Marten Meyer, Christina Parpoulas, Titouan Barthélémy, Jonas P. Becker, Jonas P. Becker, Pornpimol Charoentong, Pornpimol Charoentong, Pornpimol Charoentong, Yanhong Lyu, Selina Börsig, Selina Börsig, Nadja Bulbuc, Claudia Tessmer, Claudia Tessmer, Lisa Weinacht, David Ibberson, Patrick Schmidt, Patrick Schmidt, Rüdiger Pipkorn, Stefan B. Eichmüller, Peter Steinberger, Katharina Lindner, Katharina Lindner, Isabel Poschke, Isabel Poschke, Michael Platten, Michael Platten, Michael Platten, Michael Platten, Michael Platten, Michael Platten, Stefan Fröhling, Stefan Fröhling, Stefan Fröhling, Angelika B. Riemer, Angelika B. Riemer, Jessica C. Hassel, Maria Paula Roberti, Maria Paula Roberti, Dirk Jäger, Dirk Jäger, Inka Zörnig, Inka Zörnig, Frank Momburg, Frank Momburg   +46 more
doaj   +1 more source

HLA-E Peptide Repertoire and Dimorphism—Centerpieces in the Adaptive NK Cell Puzzle?

Frontiers in Immunology, 2018
Adaptive Natural Killer (NK) cells, a heterogenous subpopulation of human NK cells with a unique phenotypic and functional signature, became arguably one of the central areas of interest in the field.
Alexander Rölle, Alexander Rölle, Dirk Jäger, Dirk Jäger, Frank Momburg   +4 more
doaj   +1 more source

Assay format diversity in pre-clinical immunogenicity risk assessment: Toward a possible harmonization of antigenicity assays

mAbs, 2022
A major impediment to successful use of therapeutic protein drugs is their ability to induce anti-drug antibodies (ADA) that can alter treatment efficacy and safety in a significant number of patients.
Axel Ducret, Chloé Ackaert, Juliana Bessa, Campbell Bunce, Timothy Hickling, Vibha Jawa, Mark A. Kroenke, Kasper Lamberth, Anaïs Manin, Hweixian L. Penny, Noel Smith, Grzegorz Terszowski, Sophie Tourdot, Sebastian Spindeldreher   +13 more
doaj   +1 more source

T Cell Biasing by Activated Dendritic Cells [PDF]

The Journal of Immunology, 2004
Abstract We have previously reported that the ligation of FcγRs on activated macrophages affected their production of cytokines and their ability to influence T cell activation. Dendritic cells (DC) are important APCs that also express FcγR.
Charles F, Anderson, Mark, Lucas, Laila, Gutiérrez-Kobeh, Ann E, Field, David M, Mosser   +4 more
openaire   +2 more sources

Understanding the slow depletion of memory CD4(+) T cells in HIV infection [PDF]

, 2007
Background The asymptomatic phase of HIV infection is characterised by a slow decline of peripheral blood CD4(+) T cells. Why this decline is slow is not understood.
Nigel Klein, Klein Nigel, Antia, Rustom, Yates, Andrew, Callard, Robin, Antia Rustom, Yates, A, Callard, R, Klein, Nigel, Jaroslav Stark, Stark, J, Andrew Yates, Stark Jaroslav, Rustom Antia, Callard Robin, Stark, Jaroslav, Yates Andrew, Robin Callard, Klein, N, Antia, R   +19 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Single-cell transcriptome analysis of CAR T-cell products reveals subpopulations, stimulation, and exhaustion signatures

OncoImmunology, 2021
Chimeric antigen receptor (CAR) T-cell adoptive therapy is set to transform the treatment of a rapidly expanding range of malignancies. Although the activation process of normal T cells is well characterized, comparatively little is known about the ...
Xiaonan Wang, Carlotta Peticone, Ekaterini Kotsopoulou, Berthold Göttgens, Fernando J Calero-Nieto   +4 more
doaj   +1 more source

CCDC134 facilitates T cell activation through the regulation of early T cell receptor signaling

Frontiers in Immunology, 2023
Modulation of surface T cell antigen receptor (TCR) expression is crucial for proper T cell development and maintenance of mature T cell function at steady state and upon stimulation.
Tianzhuo Zhang, Qianwen Shi, Huining Gu, Biaoyi Yu, Sha Yin, Sha Yin, Qing Ge, Xiaoning Mo, Xiaofeng Liu, Jing Huang   +9 more
doaj   +1 more source

Role of phosphoinositide 3-kinases in mast cell activation [PDF]

, 2009
Mast cells are primary effector cells in allergy and chronic inflammation. Class IB (PI3Kγ) and class IA (PI3Kδ) PI3K have been shown to play major roles in mast cell activation: antigen/IgE stimulation triggers autocrine/paracrine activation of mast ...
Collmann, Emilie
core   +1 more source