Results 11 to 20 of about 15,025,843 (286)
T follicular helper cells and T follicular regulatory cells in autoimmune diseases [PDF]
Frontiers in Immunology, 2023 T follicular helper (Tfh) cells are heterogeneous and mainly characterized by expressing surface markers CXCR5, ICOS, and PD-1; cytokine IL-21; and transcription factor Bcl6.
Jingjing Qi +4 more
doaj +4 more sources
Memory T follicular helper CD4 T cells [PDF]
Frontiers in Immunology, 2015 T follicular helper (Tfh) cells are the subset of CD4 T helper cells that are required for generation and maintenance of germinal center reactions and the generation of long-lived humoral immunity.
J. Scott eHale, Rafi eAhmed
doaj +5 more sources
Immune surveillance and humoral immune responses in kidney transplantation – A look back at T follicular helper cells [PDF]
Frontiers in Immunology, 2023 T follicular helper cells comprise a specialized, heterogeneous subset of immune-competent T helper cells capable of influencing B cell responses in lymphoid tissues.
Julien Subburayalu +2 more
doaj +2 more sources
Hemato, 2022 Follicular helper T-cell (TFH) lymphomas comprise a unique group of T-cell lymphomas that represent neoplastic proliferations of follicular helper T-cells and share genetic, immunophenotypic, morphologic, and clinical features.
Karthik A. Ganapathi +2 more
doaj +2 more sources
Blood Relatives of Follicular Helper T Cells [PDF]
Immunity, 2011 Expression of the chemokine receptor CXCR5 identifies B follicular helper T cells. In this issue of Immunity, Morita et al. (2011) describe a heterogeneous circulating CXCR5(+)CD4(+) B cell helper population overrepresented in juvenile dermatomyositis patients.
Garcia De Vinuesa, Maria Carola +1 more
core +5 more sources
Follicular Helper T Cells in DiGeorge Syndrome [PDF]
Frontiers in Immunology, 2018 DiGeorge syndrome is an immunodeficiency characterized by thymic dysplasia resulting in T cell lymphopenia. Most patients suffer from increased susceptibility to infections and heightened prevalence of autoimmune disorders, such as autoimmune ...
Adam Klocperk +8 more
doaj +4 more sources
T follicular helper and T follicular regulatory cells have different TCR specificity [PDF]
Nature Communications, 2017 T follicular helper and regulatory cells are generated in the germinal centre; however, whether antigen specificity defines their differential functions is unclear.
Ana Raquel Maceiras +9 more
doaj +2 more sources
The elusive identity of T follicular helper cells
Trends in Immunology, 2010 Follicular helper T (Tfh) cells provide help to B cells and allow formation of long-lived antibody responses. Despite an improved understanding of the molecular program that drives Tfh cell formation, their definition remains elusive: neither follicular homing ability, Bcl-6 expression nor IL-21 secretion are exclusive properties of T cells that help B
Yu, Di, Vinuesa, Carola G.
core +7 more sources
Advances in the role of follicular T helper cells in graft versus host diseases
Liver Research, 2017 Graft versus host disease (GVHD) is a refractory complication of allogeneic hematopoietic stem cell transplantation for the treatment of malignant and non-malignant hematopoietic diseases.
Maogen Chen +4 more
doaj +2 more sources
T Follicular Helper Cells in Autoimmune Disorders [PDF]
Frontiers in Immunology, 2018 T follicular helper (Tfh) cells are a distinct subset of CD4+ T lymphocytes, specialized in B cell help and in regulation of antibody responses. They are required for the generation of germinal center reactions, where selection of high affinity antibody ...
Noémie Gensous +8 more
doaj +3 more sources