Results 201 to 210 of about 56,618 (238)

The Emerging Role of Tertiary Lymphoid Structures as Predictive and Prognostic Biomarkers of Immunotherapy in Cancer. [PDF]

Cancer Med
Medhin LB, Amanuel R, Warburton L, Calapre L, Amanuel B, Gray ES.   +5 more
europepmc   +1 more source

Dysregulated post‑translational modifications in granulosa cells drive ovarian dysfunction and potential infertility applications (Review). [PDF]

Int J Mol Med
Zhong Y, Zou Y, Yang Z, Wang J, Pan Z, Feng J.   +5 more
europepmc   +1 more source

Mogamulizumab-associated lymphadenopathy masquerading as lymphoma progression. [PDF]

JAAD Case Rep
Tizro P, Crisan L, Gaal K, Rosen ST, Zain J, Querfeld C.   +5 more
europepmc   +1 more source

Mixed Signals: T Cells as Architects of IgE Immunity. [PDF]

Immunol Rev
Tierney AL, Bezerra WP, Eisenbarth SC, Williams A.   +3 more
europepmc   +1 more source

Integrated Single-Cell and Spatial Multi-Omics of Clonal Precursors and Immune Niches in Germinal Center Lymphomas. [PDF]

Cancers (Basel)
Huerga-Domínguez S, Ariceta B, Aguirre-Ruiz P, San Martín-Uriz P, Sarvide S, López-Janeiro Á, Alignani D, López A, Ezponda T, Figueroa R, Grande C, Alfonso A, Pena E, Browne S, Robledano R, Vilas-Zornoza A, Roa S, Martínez-Climent JÁ, Prósper F, Canales M.   +19 more
europepmc   +1 more source

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Follicular regulatory T cells produce neuritin to regulate B cells

Cell, 2021
Regulatory T cells prevent the emergence of autoantibodies and excessive IgE, but the precise mechanisms are unclear. Here, we show that BCL6-expressing Tregs, known as follicular regulatory T (Tfr) cells, produce abundant neuritin protein that targets B cells.
Paula Gonzalez-Figueroa, Ilenia Papa, Lorena Núñez Villacís   +2 more
exaly   +3 more sources

T follicular helper cells and T follicular regulatory cells in rheumatic diseases

Nature Reviews Rheumatology, 2019
As a hallmark of autoimmune rheumatic diseases, autoantibodies have been used in diagnosis for decades. However, the immunological mechanism underlying their generation has only become clear following the identification of T follicular helper (TFH) cells and T follicular regulatory (TFR) cells. TFH cells are instrumental in supporting antibody affinity
Jun Deng, Válter R Fonseca, Luis Graca
exaly   +4 more sources

Developmental bifurcation of human T follicular regulatory cells

Science Immunology, 2021
Transcriptomics supports that human T reg cells differentiate into mature lymphoid tissue or circulating T follicular regulatory cells.
Saumya Kumar, Válter R. Fonseca, Filipa Ribeiro, Afonso P. Basto, Ana Água-Doce, Marta Monteiro, Dikélélé Elessa, Ricardo J. Miragaia, Tomás Gomes, Eliane Piaggio, Elodie Segura, Margarida Gama-Carvalho, Sarah A. Teichmann, Luis Graca   +13 more
openaire   +2 more sources

The expanding family of T follicular regulatory cells

Science Immunology, 2023
The coevolution of multiple specialized T follicular regulatory cell subsets has led to fine-tuning of human germinal center responses in providing optimal antibody production and preventing events leading to autoimmunity (see the related Research Article by Le Coz et al .).
Luis Graca, Johanne Jacobsen, Saumya Kumar   +2 more
openaire   +2 more sources

Current Advances in Follicular Regulatory T-Cell Biology

Critical Reviews in Immunology, 2022
Follicular regulatory T (T_FR) cells are a population of CD4⁺ T-cells that concomitantly express markers for regulatory T-cells and follicular helper T (T_FH) cells, and have been predominantly implicated in the regulation of humoral immunity via their suppressive functions.
Sadashib, Ghosh, Jianmei W, Leavenworth
openaire   +2 more sources