Results 211 to 220 of about 15,753,813 (238)

The Role of High Cxcl11 Expression in Ovarian Dysfunction Through NF‐κB and AKT Pathways in a Thin Endometrium Mouse Model

iNew Medicine, EarlyView.
Thin endometrium upregulates Cxcl11, which polarizes ovarian macrophages via NF‐κB/AKT, impairing ovarian function. A new uter‐ovarian signaling axis is identified. ABSTRACT Objective Thin endometrium (TE) is a recognized cause of female infertility, primarily associated with impaired uterine receptivity.
Yulu Yang, Fei Tang, Zihan Meng, Yunxi Bao, Jujun Han, Xiaohua Jiang, Jianye Wang, Ying Wang, Zhaolian Wei   +8 more
wiley   +1 more source

The influence of Epstein-Barr virus in the microenvironment of classic Hodgkin lymphoma: A focus on T-cells and macrophages. [PDF]

Hematol Transfus Cell Ther
Frota Melo AC, Buccheri V, Barbosa JA, Azevedo RS, Marques-Piubelli ML, Zerbini M.   +5 more
europepmc   +1 more source

Tissue Clearing for Lymph Nodes: 3D Mapping of Nerves and the Immune Microenvironment

iNew Medicine, EarlyView.
ABSTRACT Lymph nodes (LNs) are central hubs of adaptive immunity and key relay sites for metastatic tumour cells. However, conventional two‐dimensional histology samples only a small fraction of each node, potentially missing micrometastases and multifocal involvement while obscuring long‐range spatial relationships among tumour deposits, immune ...
Guang‐Hong Su, Fei Wang, Ting‐Hong Wei, Rui Lu, Wen‐Jun Huang, Xiang Zhang, Ling Yin, Jun Li   +7 more
wiley   +1 more source

Destroyed Melanocytes Manifested with Poliosis and Halo Nevi in Children: Proposed Immunopathophysiological Mechanisms with Emphasis on Hair Follicle Immune Privilege. [PDF]

Clin Pract
Bulat V, Paštar Z, Speeckaert R, Marušić D, Zanze L, Lugović-Mihić L.   +5 more
europepmc   +1 more source

Mechanical memory in aging: From adaptive sensing to pathological entrenchment

Interdisciplinary Medicine, EarlyView.
Mechanical memory in aging operates through four temporal tiers, from cytoskeletal remodeling to metabolic reprogramming. Aging disrupts this cascade through three distinct decoupling patterns: sensor degradation, conduction blockade, and execution failure, leading to irreversible pathological entrenchment across multiple organ systems.
Mingyang Huang, Xiaoyu Ma, Ruiqi Gao, Qichen Miao, Guoqing Wang, Ziyuan Liu, Kun Wang, Ming Luo   +7 more
wiley   +1 more source

Expression of V‑domain Ig suppressor of T cell activation in ovarian cancer and its regulation of follicular regulatory T‑cell function via the AKT/MAPK pathway. [PDF]

Oncol Rep
Ma Y, Xu Y, Yu C, Wu H, Li L.
europepmc   +1 more source

Nanoplastics: Methods, Exposure and Effects on Domestic, Farm and Wild Animals

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nanoplastics (NPs) are synthetic polymer particles ranging in size from 1 nm to 1 μm that have been identified as a major concern for ecosystems and organisms due to their plethora of negative effects. The aim of this review is to provide a comprehensive overview of the knowledge relating to exposure and effects of NPs in domestic (i.e., farm ...
B. De Felice, M. Bertazzo, A. F. Tabaran, M. Parolini, R. P. Popa, A. Pintea, L. J. Spicer, A‐L. Nagy, F. Caloni   +8 more
wiley   +1 more source

The gut microenvironment in antibody-mediated rejection: from conventional immunosuppression to precision immunomodulation in organ transplantation. [PDF]

Front Immunol
Matsuda Y.
europepmc   +1 more source

Follicular Fluid Exosomes From Diminished Ovarian Reserve Patients Impair Granulosa Cell Function via miR-135a-5p-Mediated Suppression of BIRC5. [PDF]

Mol Reprod Dev
Ruan Z, Li Z, Shu J, Lin H, Li T, Feng Y, Wang X, Wang C, Wu Z, Huang Y, Xia M, Zhao X.   +11 more
europepmc   +1 more source

An IL-21R STAT hypomorph circumvents functional redundancy in germinal centre responses. [PDF]

Elife
Jandl C, Warren J, Owens S, Batten M, Wang H, King C.   +5 more
europepmc   +1 more source